Results 11 to 20 of about 2,879,199 (294)

Origin of the Yeast Whole-Genome Duplication.

PLoS Biology, 2015
Whole-genome duplications (WGDs) are rare evolutionary events with profound consequences. They double an organism's genetic content, immediately creating a reproductive barrier between it and its ancestors and providing raw material for the divergence of
Kenneth H Wolfe
doaj   +4 more sources

Evidence for an ancient whole genome duplication in the cycad lineage.

PLoS ONE, 2017
Contrary to the many whole genome duplication events recorded for angiosperms (flowering plants), whole genome duplications in gymnosperms (non-flowering seed plants) seem to be much rarer.
Danielle Roodt, Rolf Lohaus, Lieven Sterck, Riaan L Swanepoel, Yves Van de Peer, Eshchar Mizrachi   +5 more
doaj   +5 more sources

Two rounds of whole genome duplication in the ancestral vertebrate. [PDF]

PLoS Biology, 2005
The hypothesis that the relatively large and complex vertebrate genome was created by two ancient, whole genome duplications has been hotly debated, but remains unresolved.
Paramvir Dehal, Jeffrey L Boore
doaj   +5 more sources

The collapse of gene complement following whole genome duplication [PDF]

BMC Genomics, 2010
Background Genome amplification through duplication or proliferation of transposable elements has its counterpart in genome reduction, by elimination of DNA or by gene inactivation. Whether loss is primarily due to excision of random length DNA fragments
Zhu Qian, Zheng Chunfang, Sankoff David
doaj   +4 more sources

Novelty and Convergence in Adaptation to Whole Genome Duplication [PDF]

Molecular Biology and Evolution, 2021
AbstractWhole genome duplication (WGD) can promote adaptation but is disruptive to conserved processes, especially meiosis. Studies in Arabidopsis arenosa revealed a coordinated evolutionary response to WGD involving interacting proteins controlling meiotic crossovers, which are minimized in an autotetraploid (within-species polyploid) to avoid ...
Magdalena Bohutínská, Mark Alston, Patrick Monnahan, Terezie Mandáková, Sian Bray, Pirita Paajanen, Filip Kolář, Levi Yant   +7 more
openaire   +5 more sources

Evolution after Whole-Genome Duplication: Teleost MicroRNAs [PDF]

Molecular Biology and Evolution, 2021
AbstractMicroRNAs (miRNAs) are important gene expression regulators implicated in many biological processes, but we lack a global understanding of how miRNA genes evolve and contribute to developmental canalization and phenotypic diversification. Whole-genome duplication events likely provide a substrate for species divergence and phenotypic change by ...
Thomas Desvignes, Jason Sydes, Jerôme Montfort, Julien Bobe, John H Postlethwait   +4 more
openaire   +3 more sources

ADARp150 counteracts whole genome duplication. [PDF]

Nucleic Acids Res
Abstract Impaired control of the G1/S checkpoint allows initiation of DNA replication under non-permissive conditions. Unscheduled S-phase entry is associated with DNA replication stress, demanding for other checkpoints or cellular pathways to maintain proliferation.
van Gemert F, Drakaki A, Lozano IM, de Groot D, Uiterkamp MS, Proost N, Lieftink C, van de Ven M, Beijersbergen RL, Jacobs H, Te Riele H.   +10 more
europepmc   +5 more sources

The evolutionary conundrum of whole‐genome duplication [PDF]

American Journal of Botany, 2020
The European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program.
Carretero‐Paulet, Lorenzo, Van de Peer, Yves   +1 more
openaire   +4 more sources

Model-Based Detection of Whole-Genome Duplications in a Phylogeny [PDF]

Molecular Biology and Evolution, 2020
Abstract Ancient whole-genome duplications (WGDs) leave signatures in comparative genomic data sets that can be harnessed to detect these events of presumed evolutionary importance. Current statistical approaches for the detection of ancient WGDs in a phylogenetic context have two main drawbacks.
Zwaenepoel, Arthur, Van de Peer, Yves
openaire   +3 more sources

Metabolic Adaptation after Whole Genome Duplication [PDF]

Molecular Biology and Evolution, 2009
Whole genome duplications (WGDs) have been hypothesized to be responsible for major transitions in evolution. However, the effects of WGD and subsequent gene loss on cellular behavior and metabolism are still poorly understood. Here we develop a genome scale evolutionary model to study the dynamics of gene loss and metabolic adaptation after WGD. Using
M.J.A. van Hoek (Milan), P. Hogeweg
openaire   +4 more sources