Results 11 to 20 of about 97,288 (294)
Cell type resolved expression of duplicate genes retained from whole genome duplication in Atlantic salmon [PDF]
Genome Biol EvolThe functional and evolutionary outcomes of whole genome duplication (WGD) events are driven by global remodelling of gene expression. Most investigations of gene expression changes following WGD have applied bulk transcriptomics using tissue samples ...
Taylor, Richard S +4 more
core +2 more sources
ADARp150 counteracts whole genome duplication. [PDF]
Nucleic Acids ResAbstract Impaired control of the G1/S checkpoint allows initiation of DNA replication under non-permissive conditions. Unscheduled S-phase entry is associated with DNA replication stress, demanding for other checkpoints or cellular pathways to maintain proliferation.
van Gemert F +10 more
europepmc +5 more sources
Novelty and Convergence in Adaptation to Whole Genome Duplication [PDF]
Molecular Biology and Evolution, 2021 AbstractWhole genome duplication (WGD) can promote adaptation but is disruptive to conserved processes, especially meiosis. Studies in Arabidopsis arenosa revealed a coordinated evolutionary response to WGD involving interacting proteins controlling meiotic crossovers, which are minimized in an autotetraploid (within-species polyploid) to avoid ...
Magdalena Bohutínská +7 more
openaire +5 more sources
Evolution after Whole-Genome Duplication: Teleost MicroRNAs [PDF]
Molecular Biology and Evolution, 2021 AbstractMicroRNAs (miRNAs) are important gene expression regulators implicated in many biological processes, but we lack a global understanding of how miRNA genes evolve and contribute to developmental canalization and phenotypic diversification. Whole-genome duplication events likely provide a substrate for species divergence and phenotypic change by ...
Thomas Desvignes +4 more
openaire +3 more sources
The evolutionary conundrum of whole‐genome duplication [PDF]
American Journal of Botany, 2020 The European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program.
Carretero‐Paulet, Lorenzo +1 more
openaire +4 more sources
Model-Based Detection of Whole-Genome Duplications in a Phylogeny [PDF]
Molecular Biology and Evolution, 2020 Abstract Ancient whole-genome duplications (WGDs) leave signatures in comparative genomic data sets that can be harnessed to detect these events of presumed evolutionary importance. Current statistical approaches for the detection of ancient WGDs in a phylogenetic context have two main drawbacks.
Zwaenepoel, Arthur, Van de Peer, Yves
openaire +3 more sources
Metabolic Adaptation after Whole Genome Duplication [PDF]
Molecular Biology and Evolution, 2009 Whole genome duplications (WGDs) have been hypothesized to be responsible for major transitions in evolution. However, the effects of WGD and subsequent gene loss on cellular behavior and metabolism are still poorly understood. Here we develop a genome scale evolutionary model to study the dynamics of gene loss and metabolic adaptation after WGD. Using
M.J.A. van Hoek (Milan), P. Hogeweg
openaire +4 more sources
BMC Ecology and Evolution, 2021 Background The great diversity in plant genome size and chromosome number is partly due to polyploidization (i.e. genome doubling events). The differences in genome size and chromosome number among diploid plant species can be a window into the ...
J. S. Eriksson +5 more
doaj +1 more source
A model for biased fractionation after whole genome duplication [PDF]
BMC Genomics, 2012 Paralog reduction, the loss of duplicate genes after whole genome duplication (WGD) is a pervasive process. Whether this loss proceeds gene by gene or through deletion of multi-gene DNA segments is controversial, as is the question of fractionation bias, namely whether one homeologous chromosome is more vulnerable to gene deletion than the other.As a ...
David Sankoff +2 more
openaire +2 more sources
GPCR genes are preferentially retained after whole genome duplication. [PDF]
PLoS ONE, 2008 One of the most interesting questions in biology is whether certain pathways have been favored during evolution, and if so, what properties could cause such a preference.
Jenia Semyonov +3 more
doaj +1 more source