Results 101 to 110 of about 97,288 (294)

Evolutionary history of glucose-6-phosphatase encoding genes in vertebrate lineages: towards a better understanding of the functions of multiple duplicates

BMC Genomics, 2017
Background Glucose-6-phosphate (G6pc) is a key enzyme involved in the regulation of the glucose homeostasis. The present study aims at revisiting and clarifying the evolutionary history of g6pc genes in vertebrates.
Lucie Marandel, Stéphane Panserat, Elisabeth Plagnes-Juan, Eva Arbenoits, José Luis Soengas, Julien Bobe   +5 more
doaj   +1 more source

Inverse symmetry in complete genomes and whole-genome inverse duplication. [PDF]

PLoS ONE, 2009
The cause of symmetry is usually subtle, and its study often leads to a deeper understanding of the bearer of the symmetry. To gain insight into the dynamics driving the growth and evolution of genomes, we conducted a comprehensive study of textual ...
Sing-Guan Kong, Wen-Lang Fan, Hong-Da Chen, Zi-Ting Hsu, Nengji Zhou, Bo Zheng, Hoong-Chien Lee   +6 more
doaj   +1 more source

Whole-genome duplication events of four palms.

, 2015
(A) The distribution of synonymous substitution rate (Ks) of the paralogs is displayed in red and blue for N. fruticans and P. dactylifera, respectively. Peaks I and II indicated two whole-genome duplication events in both species. The yellow bars showed
Zhang Zhang (14172), Wuxia Guo (838796), Renchao Zhou (82360), Ziwen He (217976), Suhua Shi (66594), Ying Zhang (40767)   +5 more
core   +1 more source

Lysosome‐Acidifying Nanoparticles Rescue A30P α‐Synuclein Induced Neuronal Death in Cellular and Drosophila Models of Parkinson's Disease

Advanced Healthcare Materials, EarlyView.
Lysosome‐targeted acidic nanoparticles based on a biodegradable poly(ethylene tetrafluorosuccinate‐co‐succinate) copolymer are engineered to restore impaired lysosomal acidification through pH‐responsive intracellular degradation. Localized acid release enhances autophagic proteolysis, reduces α‐synuclein accumulation, and preserves dopaminergic neuron
Chih Hung Lo, Mengda Ren, Gavin Wen Zhao Loi, Eka Norfaishanty Saipuljumri, Jonathan Indajang, Kah Leong Lim, Jialiu Zeng   +6 more
wiley   +1 more source

Studying Whole-Genome Duplication Using Experimental Evolution of Chlamydomonas

, 2023
In this chapter, we present the use of Chlamydomonas reinhardtii in experiments designed to study the evolutionary impacts of whole genome duplication. We shortly introduce the algal species and depict why it is an excellent model for experimental evolution.
Bafort, Quinten, Prost, Lucas, Aydogdu, Eylem, Van de Vloet, Antoine, Casteleyn, Griet, Van de Peer, Yves, De Clerck, Olivier   +6 more
openaire   +3 more sources

The Genome Sequence of Alpine Megacarpaea delavayi Identifies Species-Specific Whole-Genome Duplication

Frontiers in Genetics, 2020
Megacarpaea delavayi (Brassicaceae), a plant found the high mountains of southwest China at high altitudes (3000–4800 m), is used as a vegetable or medicine. Here, we report a draft genome for this species. The assembly genome of M.
Qiao Yang, Hao Bi, Wenjie Yang, Ting Li, Jiebei Jiang, Lei Zhang, Jianquan Liu, Jianquan Liu, Quanjun Hu   +8 more
doaj   +1 more source

Reply to: 'Subfunctionalization versus neofunctionalization after whole-genome duplication'.

, 2018
Reply to: 'Subfunctionalization versus neofunctionalization after whole-genome duplication'
Guiguen, Yann, Yann Guiguen, Ingo Braasch, Postlethwait, John H, Julien Bobe, John H. Postlethwait, Braasch, Ingo, Bobe, Julien   +7 more
core   +1 more source

ELABELA Targets Mitochondria to Modulate Heart Development

Advanced Science, EarlyView.
The role of peptide ELABELA (ELA) in cardiomyocyte apoptosis and congenital heart disease (CHD) is unclear. ELA deficiency caused cardiomyocyte apoptosis and CHD. A novel ELA‐APJ‐AKT‐BCL2/BAX axis in regulating mitochondrial function and contributing to CHD pathogenesis was established.
Jian Wang, Qingjie Wang, Zhikang Xu, Shuang Zhou, Yue Zhou, Junjie Yang, Lingfeng Tong, Zhuo Meng, Mei Yang, Wen Zhao, Tie Yang, Hualin Wang, Jun Zhang, Rubin Tan, Lei Wang, Yuqiang Huang, Bin Zhou, Sun Chen, Bing Zhang, Jinxiang Yuan, Jianyuan Zhao, Alex F. Chen, Kun Sun   +22 more
wiley   +1 more source

Chromosome duplication causing gene‐dosage‐based effects on the gene expression level in Gossypium hirsutum‐Gossypium australe addition lines

Plant Direct, 2020
Polyploidization, or whole‐genome duplication, leads to gene expression changes that drive the evolution of many plants and some animals. However, the role of the dosage effect on gene expression changes following genome duplication remains unclear. Here,
Shouli Feng, Min Xu, Haiyue Guo, Fujie Liu, Changjiang Cui, Ting Zhao, Baoliang Zhou   +6 more
doaj   +1 more source

Mechanisms of gene expression evolution in polyploids

, 2008
textPolyploidy, or whole genome duplication (WGD), is a fundamental evolutionary mechanism for diverse organisms including many plants and some animals. Duplicate genes from WGD are a major source of expression and functional diversity.
Ha, Misook
core