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Whole truth: resuscitating trauma patients with whole blood [PDF]
Trauma Surgery & Acute Care OpenHemorrhage remains the leading cause of death from potentially survivable injuries in both military and civilian trauma. Whole blood (WB) has repeatedly proven to be the most physiologically coherent resuscitation strategy for life-threatening hemorrhage,
Jennifer M. Gurney
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Military Medicine, 2018 Whole blood is the preferred product for resuscitation of severe traumatic hemorrhage. It contains all the elements of blood that are necessary for oxygen delivery and hemostasis, in nearly physiologic ratios and concentrations. Group O whole blood that contains low titers of anti-A and anti-B antibodies (low titer group O whole blood) can be safely ...
Andrew P Cap +2 more
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Whole blood chromium concentration is very rarely elevated independently of whole blood cobalt
Scientific Reports, 2021 Due to the risk of adverse reactions to metal debris resulting from increased wear of the arthroplasty more than one million metal-on-metal (MoM) hip replacements worldwide are in active follow-up.
Olli Lainiala +3 more
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In vitro comparison of cold‐stored whole blood and reconstituted whole blood
Vox Sanguinis, 2023 AbstractBackground and ObjectivesCold‐stored whole blood (CSWB) is increasingly used in damage control resuscitation. Haemostatic function of CSWB seems superior to that of reconstituted whole blood, and it is sufficiently preserved for 14–21 days. To provide evidence for a yet insufficiently studied aspect of prehospital CSWB use, we compared in vitro
Sanna Susila +4 more
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Frontiers in Immunology, 2023 The pathogenesis of autism spectrum disorder (ASD) is not well understood, especially in terms of immunity and inflammation, and there are currently no early diagnostic or treatment methods. In this study, we obtained six existing Gene Expression Omnibus
Hongwei Li +11 more
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Frontiers in Molecular Neuroscience, 2023 BackgroundAdult degenerative scoliosis (ADS) is forecast to be a prevalent disabling condition in an aging society. Universally, its pathogenesis is perceived as intervertebral disc degeneration (IDD), however, a thought-provoking issue is why precisely ...
Xin Shi +5 more
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Monitoring tacrolimus whole blood concentrations
Вестник трансплантологии и искусственных органов, 2020 Tacrolimus (TAC) is the primary drug for most immunosuppressive therapy regimens. It has a narrow therapeutic index, meaning that insufficient dose can lead to graft and tissue rejection, while overdose can lead to increased risk of infections, toxicity,
O. E. Gichkun
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Frontiers in Physiology, 2022 Cortisol is a robust circadian signal that synchronises peripheral circadian clocks with the central clock in the suprachiasmatic nucleus via glucocorticoid receptors that regulate peripheral gene expression.
Simon N. Archer +4 more
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Frontiers in Microbiology, 2022 Liver transplantation is widely acknowledged as the only effective treatment for end-stage liver disease, and infection is reportedly an important cause of postoperative death.
Dong Zhao +6 more
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Whole Blood Holding Time Prior to Plasma Processing Alters microRNA Expression Profile
Frontiers in Genetics, 2022 MicroRNAs (miRNAs) can exhibit aberrant expression under different physiological and pathological conditions. Therefore, differentially expressed circulating miRNAs have been a focus of biomarker discovery research. However, the use of circulating miRNAs
Sung Hye Kim +12 more
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