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Blood Coagulation Favors Anti-Inflammatory Immune Responses in Whole Blood. [PDF]

Hematol Rep
Background: We studied the effects of human blood coagulation on antioxidant activity and the cellular secretion of immunoregulatory molecules in vitro.
Seledtsov VI, Pyshenko AA, Lyubavskaya TY, Seledtsova IA, von Delwig AA.   +4 more
europepmc   +2 more sources

Whole Blood Transfusion [PDF]

Military Medicine, 2018
Whole blood is the preferred product for resuscitation of severe traumatic hemorrhage. It contains all the elements of blood that are necessary for oxygen delivery and hemostasis, in nearly physiologic ratios and concentrations. Group O whole blood that contains low titers of anti-A and anti-B antibodies (low titer group O whole blood) can be safely ...
Cap, Andrew P., Beckett, Andrew, Benov, Avi, Borgman, Matthew, Chen, Jacob, Corley, Jason B., Doughty, Heidi, Fisher, Andrew, Glassberg, Elon, Gonzales, Richard, Kane, Shawn F., Malloy, Wilbur W., Nessen, Shawn, Perkins, Jeremy G., Prat, Nicolas, Quesada, Jose, Reade, Michael, Sailliol, Anne, Spinella, Philip C., Stockinger, Zsolt, Strandenes, Geir, Taylor, Audra, Yazer, Mark, Bryant, Barbara, Gurney, Jennifer   +24 more
openaire   +4 more sources

Whole blood chromium concentration is very rarely elevated independently of whole blood cobalt

Scientific Reports, 2021
Due to the risk of adverse reactions to metal debris resulting from increased wear of the arthroplasty more than one million metal-on-metal (MoM) hip replacements worldwide are in active follow-up.
Olli Lainiala, Mari Karsikas, Aleksi Reito, Antti Eskelinen   +3 more
doaj   +1 more source

Imaging Erythrocyte Sedimentation in Whole Blood

Frontiers in Physiology, 2022
The erythrocyte sedimentation rate (ESR) is one of the oldest medical diagnostic tools. However, currently there is some debate on the structure formed by the cells during the sedimentation process.
Alexis Darras, Hans Georg Breunig, Thomas John, Renping Zhao, Johannes Koch, Carsten Kummerow, Karsten König, Karsten König, Christian Wagner, Christian Wagner, Lars Kaestner, Lars Kaestner   +11 more
doaj   +1 more source

Blood pressure and expression of microRNAs in whole blood. [PDF]

PLoS ONE, 2017
BACKGROUND:Blood pressure (BP) is a complex, multifactorial clinical outcome driven by genetic susceptibility, behavioral choices, and environmental factors.
Zhou Zhang, Brian Thomas Joyce, Jacob K Kresovich, Yinan Zheng, Jia Zhong, Ruchi Patel, Wei Zhang, Lei Liu, Chang Dou, John P McCracken, Anaité Díaz, Valeria Motta, Marco Sanchez-Guerra, Shurui Bian, Pier Alberto Bertazzi, Joel Schwartz, Andrea A Baccarelli, Sheng Wang, Lifang Hou   +18 more
doaj   +1 more source

Novel insights into the immune cell landscape and gene signatures in autism spectrum disorder by bioinformatics and clinical analysis

Frontiers in Immunology, 2023
The pathogenesis of autism spectrum disorder (ASD) is not well understood, especially in terms of immunity and inflammation, and there are currently no early diagnostic or treatment methods. In this study, we obtained six existing Gene Expression Omnibus
Hongwei Li, Yiran Xu, Yiran Xu, Wenhua Li, Lingling Zhang, Xiaoli Zhang, Bingbing Li, Yiwen Chen, Xiaoyang Wang, Xiaoyang Wang, Changlian Zhu, Changlian Zhu   +11 more
doaj   +1 more source

Monitoring tacrolimus whole blood concentrations

Вестник трансплантологии и искусственных органов, 2020
Tacrolimus (TAC) is the primary drug for most immunosuppressive therapy regimens. It has a narrow therapeutic index, meaning that insufficient dose can lead to graft and tissue rejection, while overdose can lead to increased risk of infections, toxicity,
O. E. Gichkun
doaj   +1 more source

Whole-transcriptome sequencing identifies key differentially expressed circRNAs/lncRNAs/miRNAs/mRNAs and linked ceRNA networks in adult degenerative scoliosis

Frontiers in Molecular Neuroscience, 2023
BackgroundAdult degenerative scoliosis (ADS) is forecast to be a prevalent disabling condition in an aging society. Universally, its pathogenesis is perceived as intervertebral disc degeneration (IDD), however, a thought-provoking issue is why precisely ...
Xin Shi, Xin Shi, Panpan Li, Panpan Li, Xiang Wu, Jun Shu   +5 more
doaj   +1 more source

Mistimed sleep and waking activity in humans disrupts glucocorticoid signalling transcripts and SP1, but not plasma cortisol rhythms

Frontiers in Physiology, 2022
Cortisol is a robust circadian signal that synchronises peripheral circadian clocks with the central clock in the suprachiasmatic nucleus via glucocorticoid receptors that regulate peripheral gene expression.
Simon N. Archer, Carla S. Möller-Levet, Emma E. Laing, Derk-Jan Dijk, Derk-Jan Dijk   +4 more
doaj   +1 more source

In vitro comparison of cold‐stored whole blood and reconstituted whole blood

Vox Sanguinis, 2023
AbstractBackground and ObjectivesCold‐stored whole blood (CSWB) is increasingly used in damage control resuscitation. Haemostatic function of CSWB seems superior to that of reconstituted whole blood, and it is sufficiently preserved for 14–21 days. To provide evidence for a yet insufficiently studied aspect of prehospital CSWB use, we compared in vitro
Sanna Susila, Tuukka Helin, Jouni Lauronen, Lotta Joutsi‐Korhonen, Minna Ilmakunnas   +4 more
openaire   +3 more sources