Results 1 to 10 of about 2,979,162 (310)

Whole Blood Transfusion [PDF]

open access: yesMilitary Medicine, 2018
Whole blood is the preferred product for resuscitation of severe traumatic hemorrhage. It contains all the elements of blood that are necessary for oxygen delivery and hemostasis, in nearly physiologic ratios and concentrations. Group O whole blood that contains low titers of anti-A and anti-B antibodies (low titer group O whole blood) can be safely ...
Cap, Andrew P.   +24 more
openaire   +4 more sources

Low specificity of determine HIV1/2 RDT using whole blood in south west Tanzania [PDF]

open access: yes, 2012
Objective: To evaluate the diagnostic performance of two rapid detection tests (RDTs) for HIV 1/2 in plasma and in whole blood samples. Methods: More than 15,000 study subjects above the age of two years participated in two rounds of a cohort study to ...
A Halkin   +31 more
core   +8 more sources

In vitro comparison of cold‐stored whole blood and reconstituted whole blood

open access: yesVox Sanguinis, 2023
AbstractBackground and ObjectivesCold‐stored whole blood (CSWB) is increasingly used in damage control resuscitation. Haemostatic function of CSWB seems superior to that of reconstituted whole blood, and it is sufficiently preserved for 14–21 days. To provide evidence for a yet insufficiently studied aspect of prehospital CSWB use, we compared in vitro
Sanna Susila   +4 more
openaire   +3 more sources

Shear viscosity and nonlinear behaviour of whole blood under large amplitude oscillatory shear [PDF]

open access: yes, 2013
We investigated experimentally the rheological behavior of whole human blood subjected to large amplitude oscillatory shear under strain control to assess its nonlinear viscoelastic response.
Alves, M.A.   +6 more
core   +1 more source

Stability of proinsulin in whole blood [PDF]

open access: yesClinical Biochemistry, 2018
Proinsulin, the precursor for insulin, is secreted in higher concentrations when β-cells are under stress and previous studies have shown that elevated proinsulin could be used as a marker for individuals in a pre-diabetic state. The aim of this study was to assess the stability of proinsulin across a wide concentration range (3-882 and 2-187pmol/L ...
Stephen D. Luzio   +3 more
openaire   +4 more sources

Automated processing of whole blood samples for the determination of immunosuppressants by liquid chromatography tandem-mass spectrometry [PDF]

open access: yes, 2006
Background: Liquid chromatography tandem-mass spectrometry (LC-MS/MS) is an efficient technology for routine determination of immunosuppressants in whole blood; however, time-consuming manual sample preparation remains a significant limitation of this ...
Spöhrer, Ute, Vogeser, Michael
core   +1 more source

HLA gene expression is altered in whole blood and placenta from women who later developed preeclampsia [PDF]

open access: yes, 2017
Preeclampsia is a multi-system disease that significantly contributes to maternal and fetal morbidity and mortality. In this study, we used a non-biased microarray approach to identify dysregulated genes in maternal whole blood samples which may be ...
Akehurst, Christine   +8 more
core   +1 more source

Spaceflight modulates gene expression in the whole blood of astronauts [PDF]

open access: yes, 2016
Astronauts are exposed to a unique combination of stressors during spaceflight, which leads to alterations in their physiology and potentially increases their susceptibility to disease, including infectious diseases.
Barrila, Jennifer   +7 more
core   +2 more sources

Self-powered microfluidic chips for multiplexed protein assays from whole blood [PDF]

open access: yes, 2009
We report herein on a self-powered, self-contained microfluidic-based chip designed to separate plasma from whole blood, and then execute an assay of a multiplexed panel of plasma biomarker proteins.
Heath, James R.   +3 more
core   +2 more sources

Deep-coverage whole genome sequences and blood lipids among 16,324 individuals. [PDF]

open access: yes, 2018
Large-scale deep-coverage whole-genome sequencing (WGS) is now feasible and offers potential advantages for locus discovery. We perform WGS in 16,324 participants from four ancestries at mean depth >29X and analyze genotypes with four quantitative ...
Abecasis, Goncalo   +36 more
core   +2 more sources

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