Results 1 to 10 of about 1,422,812 (269)

Whole blood chromium concentration is very rarely elevated independently of whole blood cobalt

open access: yesScientific Reports, 2021
Due to the risk of adverse reactions to metal debris resulting from increased wear of the arthroplasty more than one million metal-on-metal (MoM) hip replacements worldwide are in active follow-up.
Olli Lainiala   +3 more
doaj   +1 more source

Therapeutic Drug Monitoring of Tacrolimus Based on Volumetric Absorptive Microsampling Technique (VAMS) in Renal Transplant Pediatric Recipients—LC-MS/MS Method Development, Hematocrit Effect Evaluation, and Clinical Application

open access: yesPharmaceutics, 2023
Tacrolimus (TAC) is post-transplant pharmacotherapy’s most widely used immunosuppressant. In routine clinical practice, frequent uncomfortable venipuncture is necessary for whole-blood (WB) collection to check trough TAC levels.
Arkadiusz Kocur   +4 more
doaj   +1 more source

Blood pressure and expression of microRNAs in whole blood. [PDF]

open access: yesPLoS ONE, 2017
BACKGROUND:Blood pressure (BP) is a complex, multifactorial clinical outcome driven by genetic susceptibility, behavioral choices, and environmental factors.
Zhou Zhang   +18 more
doaj   +1 more source

Monitoring tacrolimus whole blood concentrations

open access: yesВестник трансплантологии и искусственных органов, 2020
Tacrolimus (TAC) is the primary drug for most immunosuppressive therapy regimens. It has a narrow therapeutic index, meaning that insufficient dose can lead to graft and tissue rejection, while overdose can lead to increased risk of infections, toxicity,
O. E. Gichkun
doaj   +1 more source

Real time-PCR, ELISA, as an identification methods for Detection respiratory syncytial virus in children

open access: yesTikrit Journal of Pure Science, 2023
The study have been done to detecting HRSV infections among hospitalized children under 10 years old in Salahaldin Governorate, in addition to compare different diagnostic methods for detection of this virus.
Suad H. AL-Bashar   +2 more
doaj   +1 more source

Blood and Plasma Volumetric Absorptive Microsampling (VAMS) Coupled to LC-MS/MS for the Forensic Assessment of Cocaine Consumption

open access: yesMolecules, 2020
Reliable, feasible analytical methods are needed for forensic and anti-doping testing of cocaine and its most important metabolites, benzoylecgonine, ecgonine methyl ester, and cocaethylene (the active metabolite formed in the presence of ethanol).
Roberto Mandrioli   +2 more
doaj   +1 more source

Determination of 19 Psychoactive Substances in Premortem and Postmortem Whole Blood Samples Using Ultra-High-Performance Liquid Chromatography–Tandem Mass Spectrometry

open access: yesSeparations, 2021
An ever-increasing need exists within the forensic laboratories to develop analytical processes for the qualitative and quantitative determination of a broad spectrum of new psychoactive substances.
Sevasti Karampela   +2 more
doaj   +1 more source

A Flow Cytometry-Based Whole Blood Natural Killer Cell Cytotoxicity Assay Using Overnight Cytokine Activation

open access: yesFrontiers in Immunology, 2020
Background: Measurement of natural killer (NK) cell function has important clinical utility in several diseases. Although the flow cytometry (FC)-based 4-h NK cytotoxicity assay using peripheral blood mononuclear cells (PBMCs) in the clinical laboratory ...
Jinho Kim   +12 more
doaj   +1 more source

Monitoring NLRP3 Inflammasome Activation and Exhaustion in Clinical Samples: A Refined Flow Cytometry Protocol for ASC Speck Formation Measurement Directly in Whole Blood after Ex Vivo Stimulation

open access: yesCells, 2022
Alteration of NLRP3 inflammasome pathway including hyper-activation or exhaustion has been implicated in the pathophysiology of many diseases. Following cell stimulation, aggregation of the ASC protein into a multiprotein complex, the ASC speck, has been
Rémy Coudereau   +6 more
doaj   +1 more source

Comparative evaluation of platelet count in whole blood and injectable platelet-rich fibrin

open access: yesDentistry and Medical Research, 2021
Background: Platelets are formed from megakaryocytes and platelets are present in the circulation for 5–7 days. Platelets are essential in hemostasis, vascular integrity, angiogenesis, inflammation, innate immunity, and wound healing.
Aarati Nayak   +4 more
doaj   +1 more source

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