Results 1 to 10 of about 3,122,731 (363)

Whole blood chromium concentration is very rarely elevated independently of whole blood cobalt

Scientific Reports, 2021
Due to the risk of adverse reactions to metal debris resulting from increased wear of the arthroplasty more than one million metal-on-metal (MoM) hip replacements worldwide are in active follow-up.
Olli Lainiala, Mari Karsikas, Aleksi Reito, Antti Eskelinen   +3 more
doaj   +1 more source

Whole Blood Transfusion [PDF]

Military Medicine, 2018
Whole blood is the preferred product for resuscitation of severe traumatic hemorrhage. It contains all the elements of blood that are necessary for oxygen delivery and hemostasis, in nearly physiologic ratios and concentrations. Group O whole blood that contains low titers of anti-A and anti-B antibodies (low titer group O whole blood) can be safely ...
Cap, Andrew P., Beckett, Andrew, Benov, Avi, Borgman, Matthew, Chen, Jacob, Corley, Jason B., Doughty, Heidi, Fisher, Andrew, Glassberg, Elon, Gonzales, Richard, Kane, Shawn F., Malloy, Wilbur W., Nessen, Shawn, Perkins, Jeremy G., Prat, Nicolas, Quesada, Jose, Reade, Michael, Sailliol, Anne, Spinella, Philip C., Stockinger, Zsolt, Strandenes, Geir, Taylor, Audra, Yazer, Mark, Bryant, Barbara, Gurney, Jennifer   +24 more
openaire   +3 more sources

Novel insights into the immune cell landscape and gene signatures in autism spectrum disorder by bioinformatics and clinical analysis

Frontiers in Immunology, 2023
The pathogenesis of autism spectrum disorder (ASD) is not well understood, especially in terms of immunity and inflammation, and there are currently no early diagnostic or treatment methods. In this study, we obtained six existing Gene Expression Omnibus
Hongwei Li, Yiran Xu, Yiran Xu, Wenhua Li, Lingling Zhang, Xiaoli Zhang, Bingbing Li, Yiwen Chen, Xiaoyang Wang, Xiaoyang Wang, Changlian Zhu, Changlian Zhu   +11 more
doaj   +1 more source

Whole-transcriptome sequencing identifies key differentially expressed circRNAs/lncRNAs/miRNAs/mRNAs and linked ceRNA networks in adult degenerative scoliosis

Frontiers in Molecular Neuroscience, 2023
BackgroundAdult degenerative scoliosis (ADS) is forecast to be a prevalent disabling condition in an aging society. Universally, its pathogenesis is perceived as intervertebral disc degeneration (IDD), however, a thought-provoking issue is why precisely ...
Xin Shi, Xin Shi, Panpan Li, Panpan Li, Xiang Wu, Jun Shu   +5 more
doaj   +1 more source

Monitoring tacrolimus whole blood concentrations

Вестник трансплантологии и искусственных органов, 2020
Tacrolimus (TAC) is the primary drug for most immunosuppressive therapy regimens. It has a narrow therapeutic index, meaning that insufficient dose can lead to graft and tissue rejection, while overdose can lead to increased risk of infections, toxicity,
O. E. Gichkun
doaj   +1 more source

Mistimed sleep and waking activity in humans disrupts glucocorticoid signalling transcripts and SP1, but not plasma cortisol rhythms

Frontiers in Physiology, 2022
Cortisol is a robust circadian signal that synchronises peripheral circadian clocks with the central clock in the suprachiasmatic nucleus via glucocorticoid receptors that regulate peripheral gene expression.
Simon N. Archer, Carla S. Möller-Levet, Emma E. Laing, Derk-Jan Dijk, Derk-Jan Dijk   +4 more
doaj   +1 more source

Diagnostic Value and Clinical Application of mNGS for Post-Liver Transplantation Infection: A Cross-Sectional Study With Case Reports

Frontiers in Microbiology, 2022
Liver transplantation is widely acknowledged as the only effective treatment for end-stage liver disease, and infection is reportedly an important cause of postoperative death.
Dong Zhao, Liping Guo, Dongli Lian, Yuchen Gu, Xu Yan, Hongxing Hu, Jing Yuan   +6 more
doaj   +1 more source

Whole Blood Holding Time Prior to Plasma Processing Alters microRNA Expression Profile

Frontiers in Genetics, 2022
MicroRNAs (miRNAs) can exhibit aberrant expression under different physiological and pathological conditions. Therefore, differentially expressed circulating miRNAs have been a focus of biomarker discovery research. However, the use of circulating miRNAs
Sung Hye Kim, Sung Hye Kim, David A. MacIntyre, David A. MacIntyre, Lynne Sykes, Lynne Sykes, Maria Arianoglou, Maria Arianoglou, Phillip R. Bennett, Phillip R. Bennett, Vasso Terzidou, Vasso Terzidou, Vasso Terzidou   +12 more
doaj   +1 more source

Pharmacokinetics of Mephedrone Enantiomers in Whole Blood after a Controlled Intranasal Administration to Healthy Human Volunteers

Pharmaceuticals, 2020
Mephedrone, which is one of the most popular synthetic cathinones, has one chiral centre and thus exists as two enantiomers: R-(+)-mephedrone and S-(−)-mephedrone.
Joanna Czerwinska, Mark C. Parkin, Agostino Cilibrizzi, Claire George, Andrew T. Kicman, Paul I. Dargan, Vincenzo Abbate   +6 more
doaj   +1 more source

Intravenous Iron Sucrose versus Packed Cell Volume for Treatment of Severe Iron Deficiency Anaemia in Pregnancy: A Randomization Clinical Trial [PDF]

Journal of Clinical and Diagnostic Research, 2019
Introduction: Severe Iron Deficiency Anaemia (IDA) in pregnancy is usually treated with whole blood or Packed Cell Volume (PCV) transfusion to maintain feto-placental perfusion and replete the haemodynamic mechanisms before delivery.
Girija Wagh
doaj   +1 more source