Results 91 to 100 of about 3,996,555 (297)

Phase II study of whole brain radiotherapy with or without erlotinib in patients with multiple brain metastases from lung adenocarcinoma

, 2013
Hongqing Zhuang,1–4 Zhiyong Yuan,1–4 Jun Wang,1–4 Lujun Zhao,1–4 Qingsong Pang,1–4 Ping Wang1–41Department of Radiotherapy, Tianjin Medical University Cancer Institute and Hospital, 2National Clinical Research Center ...
Zhao L, Wang P, Pang Q, Zhuang H, Wang J, Yuan Z   +5 more
core  

The treatment of patients with 1-3 brain metastases: is there a place for whole brain radiotherapy alone, yet? A retrospective analysis

, 2015
To evaluate the efficacy of whole brain radiotherapy (WBRT) with or without other treatments in patients (pts) with 1-3 brain metastases (BM)
PEDRETTI, Sara, PADOVANI, Alessandro, Buttolo, Luciano, BUGLIONE DI MONALE E BASTIA, Michela, POLIANI, Pietro Luigi, PEGURRI, Ludovica, GHIRARDELLI, Paolo, TRIGGIANI, Luca, BORGHETTI, Paolo, Liserre, Roberto, GIPPONI, Stefano, MAGRINI, Stefano Maria, Panciani, Paolo, Pasinetti, Nadia, PANDINI, Sara Angela, COSTA, Loredana   +15 more
core   +1 more source

Acoustically Activatable Drug‐Loaded Nanodroplets for Mechanochemical Therapy in Solid Tumors

Advanced Science, EarlyView.
Microfluidically fabricated drug‐loaded nanodroplets are sequentially activated by dual‐frequency ultrasound through acoustic droplet vaporization followed by bubble collapse, enabling spatially controlled drug release and mechanical tumor fractionation, resulting in synergistic mechanochemotherapy and prolonged survival.
Tiran Bercovici, Mike Bismuth, Meir Goldsmith, Dan Peer, Tali Ilovitsh   +4 more
wiley   +1 more source

THERAPEUTIC EFFECTS OF WHOLE BRAIN RADIOTHERAPY WITH CARBOPLATIN AS RADIATION SENSITIZER IN MANAGEMENT OF BRAIN METASTASIS

Pakistan Armed Forces Medical Journal, 2013
Aim: To determine the efficacy of whole brain radiotherapy (WBRT) with carboplatin as radiation sensitizer in metastatic brain disease in our adult population. Study Design: Quasi-experimental study.
Dr Zeeshan Ahmed Alvi, Ahsan Mahmood ., Usman Ali ., Shahid Rasul ., Talha Maqsood ., Saira Ahmed ., Saima Ishtiaq ., Salman Arif .   +7 more
doaj   +2 more sources

In the context of the era of targeted therapy: evaluation of the survival benefits of different local treatment modalities for patients with 1–3 brain metastases from non-small cell lung cancer

Scientific Reports
Advances in molecular biology have extended survival for lung cancer patients with brain metastases. However, radiotherapy and surgery remain standard for non-small cell lung cancer (NSCLC) brain metastases.
Liang Sun, Haibin Chen, Zhi Yang, Liwen Li, Zhaohui ying, Yuanyuan Qu, Nanyang Tong, Caixing Sun, Liang Xia   +8 more
doaj   +1 more source

Biomarkers of Brain Damage Induced by Radiotherapy

Dose-Response, 2020
Radiotherapy remains currently a critical component for both primary and metastatic brain tumors either alone or in combination with surgery, chemotherapy, and molecularly targeted agents, while it could cause simultaneously normal brain tissue injury ...
Nahida Sultana, Chao Sun, Takanori Katsube, Bing Wang   +3 more
doaj   +1 more source

Optimizing Cancer Vaccinations Using a Physiologically‐Based Pharmacokinetic/Pharmacodynamic (PBPK/PD) Model

Advanced Science, EarlyView.
Where and when should a cancer vaccine be administered? A whole‐body PBPK model demonstrates that systemic immune transport critically determines vaccination efficacy. By simulating how organ‐specific immune interactions influence treatment response, the study provides a quantitative framework for optimizing cancer vaccination strategies.
Mohammad R. Nikmaneshi, Timothy P. Padera, Lance L. Munn   +2 more
wiley   +1 more source

CAQ Corner: Immune‐mediated complications

, 2022
Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley   +1 more source

Radiosurgery or Fractionated Stereotactic Radiotherapy plus Whole-brain Radioherapy in Brain Oligometastases: A Long-term Analysis

, 2015
To analyze the outcome of patients with brain oligometastases treated by radiosurgery (SRS) or fractionated stereotactic radiotherapy (FSRT) after whole-brain radiotherapy (WBRT)
Mazzarella, Ciro, Ferro, Marica, Fersino, Sergio, Fiorentino, Alba, Frascino, Vincenzo, Valentini, Vincenzo, Azario, Luigi, Colosimo, Cesare, D'Agostino, Giuseppe Roberto, Autorino, Rosa, Pompucci, A, Balducci, Mario, Chiesa, Silvia, Mattiucci, Gian Carlo, Anile, Carmelo   +14 more
core  

Role of radiotherapy in the management of brain metastases of NSCLC – Decision criteria in clinical routine

, 2021
Background: Whole brain radiotherapy (WBRT) is a common treatment option for brain metastases secondary to non-small cell lung cancer (NSCLC). Data from the QUARTZ trial suggest that WBRT can be omitted in selected patients and treated with optimal ...
Peeters, Stephanie T.H., McDonald, Fiona, Glatzer, Markus, Widder, Joachim, Geets, Xavier, Belderbos, José, Andratschke, Nicolaus, Nestle, Ursula, Guckenberger, Matthias, Van Houtte, Paul, Ramella, Sara, Slotman, Ben J., Lievens, Yolande, Dieckmann, Karin, Le Pechoux, Cecile, Dziadziuszko, Rafal, Putora, Paul Martin, Faivre-Finn, Corinne, Pöttgen, Christoph, De Ruysscher, Dirk, Ricardi, Umberto, Süveg, Krisztian, Troost, Esther G.C., Manapov, Farkhad   +23 more
core   +1 more source