Results 81 to 90 of about 3,996,555 (297)

Whole brain radiotherapy with a conformational external beam radiation boost for lung cancer patients with 1-3 brain metastasis: a multi institutional study

, 2010
To determine the outcome of patients with brain metastasis (BM) from lung cancer treated with an external beam radiotherapy boost (RTB) after whole brain radiotherapy (WBRT).Universitätsklinik für Radio ...
Casanova, Nathalie, Combescure, Christophe, Mazouni, Zohra, Bieri, Sabine, Weber, Damien C, Pica, Alessia   +5 more
core   +1 more source

Spatiotemporal Multi‐Omic Mapping Reveals Liver‐Muscle Metabolic Crosstalk in Cancer Cachexia

Advanced Science, EarlyView.
The interactive CCAtlas platform delineates cross‐species, spatiotemporal, and sex‐specific molecular dynamics and metabolic rewiring across organs during cancer cachexia. Hepatic Gamt downregulation curtails hepatic creatine synthesis to trigger systemic creatine insufficiency and consequent skeletal muscle atrophy in LLC tumour‐bearing mice ...
Zihan Tian, Qianyu Wang, Wenyan Gao, Xianfeng Li, Jiawen Fan, Xiaoliang Wu, Siqi Liu, Xiangdong Ming, Danna Yeerken, Mutian Shen, Qingjie Min, Qimin Zhan, Yan Wang   +12 more
wiley   +1 more source

Stereotactic radiotherapy versus whole-brain radiotherapy for brain metastases

Moždane metastaze su najčešće dijagnosticirani maligni tumori središnjeg živčanog sustava, a uslijed napretka u dijagnostici i liječenju njihova incidencija i dalje raste.
Lipovac, Josip
core   +2 more sources

Efficacy and toxicity of whole brain radiotherapy in patients with multiple cerebral metastases from malignant melanoma

Radiation Oncology, 2012
Background To retrospectively access outcome and toxicity of whole brain radiotherapy (WBRT) in patients with multiple brain metastases (BM) from malignant melanoma (MM).
Hauswald Henrik, Dittmar Jan-Oliver, Habermehl Daniel, Rieken Stefan, Sterzing Florian, Debus Jürgen, Combs Stephanie E   +6 more
doaj   +1 more source

Discovery and Optimization of AMT‐676, a CDH17‐Targeting ADC for the Treatment of Advanced Gastrointestinal Cancers

Advanced Science, EarlyView.
AMT‐676 is a novel antibody‐drug conjugate targeting CDH17, an adhesion molecule uniquely exposed on gastrointestinal tumor surfaces. Engineered with an optimized exatecan payload, it demonstrates profound tumor regression and a robust bystander effect across diverse preclinical models.
Ying‐nan Wang, Dan‐yun Ruan, Jing Shi, Yue Huang, Hui Sheng, Ya‐ling Huang, Linjie Ma, Lijun Wang, Caiwei Chen, Yixuan Wang, Yue Zhang, Yi Shen, Qing Zhang, Jianjian Zhang, Yanfang Tang, Jin‐ling Zhang, Jia‐jia Hu, Chen‐yi Wu, Jia‐ying Chen, Xun Meng, Shu‐Hui Liu, Feng Wang   +21 more
wiley   +1 more source

Palliative whole-brain radiotherapy and health-related quality of life for patients with brain metastasis in cancer

, 2015
Ying Gao,1,* Fei Gao,2,* Jin-lu Ma,1 Dong-li Zhao1 1Department of Radiotherapy Oncology, First Affiliated Hospital of Xi’an Jiaotong University, 2Department of Neurology, First Affiliated Hospital of Xi’an Medical University, Xi’an ...
Ma JL, Gao Y, Gao F, Zhao DL
core  

Parotid glands in whole-brain radiotherapy: 2D versus 3D technique for no sparing or sparing

, 2015
PURPOSE: Whole-brain radiotherapy is performed as standard therapy in patients with multiple brain metastases and in patients with more favourable prognosis such as lymphoma and small-cell lung carcinoma in the prophylactic setting.
Di Pilla, A, Augurio, A, DI TOMMASO, MONICA, DI NICOLA, MARTA, VINCIGUERRA, ANNAMARIA, TRIGNANI, MARIANNA, GENOVESI, Domenico, Cèfaro, G. A   +7 more
core   +1 more source

Targeting LDHA Palmitoylation Sensitizes GBM to Chemoradiotherapy via Suppressing Palmitic Acid Induced Glycolytic Reprogramming

Advanced Science, EarlyView.
Mesenchymal GSCs preferentially uptake palmitic acid, thereby promoting ZDHHC12‐mediated LDHA palmitoylation. This modification enhances LDHA enzymatic activity, drives glycolytic reprogramming, and facilitates exosomal LDHA‐mediated TAM regulation.
Zijie Gao, Rongrong Zhao, Zheyuan Chen, Qingtong Wang, Huanyu Yang, Boyan Li, Yanhua Qi, Shulin Zhao, Jixing Zhao, Jiawei Qiu, Ziwen Pan, Zhe Han, Ruochuan Li, Huize Xia, Weijie Tang, Xing Guo, Ping Zhang, Hongyu Zhao, Xu Qian, Gang Li, Hao Xue   +20 more
wiley   +1 more source

Is Whole‐Brain Radiotherapy for Brain Metastases an Overestimated Therapy? A Retrospective Study of Real‐World Data Using Landmark Analyses

Cancer Medicine
Background The role of whole‐brain radiotherapy for patients with brain metastases is changing as immunotherapy and molecularly targeted therapies advance. However, whole‐brain radiotherapy continues to be part of the multimodal concept.
Florian Hoelzl, Oliver Koelbl, Isabella Gruber   +2 more
doaj   +1 more source

Meta‐analysis of whole‐brain radiotherapy plus temozolomide compared with whole‐brain radiotherapy for the treatment of brain metastases from non‐small‐cell lung cancer

Cancer Medicine, 2018
The aim of this meta‐analysis was to compare the efficiency of whole‐brain radiotherapy (WBRT) plus temozolomide (TMZ) with WBRT for the treatment of brain metastases from non‐small‐cell lung cancer (NSCLC).
Yong Xin, WenWen Guo, Chun Sheng Yang, Qian Huang, Pei Zhang, Long Zhen Zhang, Guan Jiang   +6 more
doaj   +1 more source