Results 51 to 60 of about 2,879,199 (292)
, 2022 International audienceTeleost fishes are ancient tetraploids stemming from an ancestral whole-genome duplication that may have contributed to the impressive diversification of this clade.
Guiguen, Yann +12 more
core +1 more source
Laser microdissection of FFPE tissue areas and subsequent whole genome amplification by Ampli1TM
, 2022 S.141-162Laser microdissection (LMD) and whole genome amplification (WGA) are valuable tools to isolate, purify, and genetically analyze cancer cells from tissue sections.
Czyz, Zbigniew Tadeusz +2 more
core +1 more source
Evolution After Whole-Genome Duplication: A Network Perspective [PDF]
G3 Genes|Genomes|Genetics, 2013 AbstractGene duplication plays an important role in the evolution of genomes and interactomes. Elucidating how evolution after gene duplication interplays at the sequence and network level is of great interest. In this work, we analyze a data set of gene pairs that arose through whole-genome duplication (WGD) in yeast.
Zhu, Yun, Lin, Zhenguo, Nakhleh, Luay
openaire +3 more sources
The impact of genome triplication on tandem gene evolution in Brassica rapa
Frontiers in Plant Science, 2012 Whole genome duplication (WGD) and tandem duplication (TD) are both important modes of gene expansion. However, how whole genome duplication influences tandemly duplicated genes is not well studied.
Lu eFang +3 more
doaj +1 more source
The low recombining pericentromeric region of barley restricts gene diversity and evolution but not gene expression [PDF]
, 2014 The low-recombining pericentromeric region of the barley genome contains roughly a quarter of the genes of the species, embedded in low recombining DNA that is rich in repeats and repressive chromatin signatures.
Dhillon, Taniya +17 more
core +1 more source
Sturgeon-Paddlefish Whole Genome Duplication Data
, 2023 Contains Code and Raw Data for Redmond et al 2023, Independent rediploidization masks shared whole genome duplication in the sturgeon-paddlefish ...
Manu Kumar Gundappa (15377978) +4 more
core +1 more source
Rearrangement Rate following the Whole-Genome Duplication in Teleosts [PDF]
Molecular Biology and Evolution, 2006 It is now clear that a whole-genome duplication (WGD) occurred at the base of the teleost fish lineage. Like the other anciently polyploid genomes investigated so far, teleost genomes now behave like diploids with chromosomes forming pairs at meiosis. The diploidization process is currently poorly understood.
Marie, Sémon, Kenneth H, Wolfe
openaire +2 more sources
Whole-Genome Duplication and Genome Instability in Cancer Cells: Double the Trouble
International Journal of Molecular Sciences, 2023 Whole-genome duplication (WGD) is one of the most common genomic abnormalities in cancers. WGD can provide a source of redundant genes to buffer the deleterious effect of somatic alterations and facilitate clonal evolution in cancer cells. The extra DNA and centrosome burden after WGD is associated with an elevation of genome instability.
Tsz Yin Lau, Randy Y.C. Poon
openaire +3 more sources
Principles of whole-genome amplification
, 2022 S.1-14Modern molecular biology relies on large amounts of high-quality genomic DNA. However, in a number of clinical or biological applications this requirement cannot be met, as starting material is either limited (e.g., preimplantation genetic ...
Czyz, Zbigniew Tadeusz +2 more
core +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source