Results 31 to 40 of about 2,879,199 (292)

Mechanisms of gene duplication and translocation and progress towards understanding their relative contributions to animal genome evolution [PDF]

, 2012
Duplication of genetic material is clearly a major route to genetic change, with consequences for both evolution and disease. A variety of forms and mechanisms of duplication are recognised, operating across the scales of a few base pairs upto entire ...
Mendivil Ramos, Olivia, Ferrier, David Ellard Keith   +1 more
core   +1 more source

Parallel evolution of amphioxus and vertebrate small-scale gene duplications

Genome Biology, 2022
Background Amphioxus are non-vertebrate chordates characterized by a slow morphological and molecular evolution. They share the basic chordate body-plan and genome organization with vertebrates but lack their 2R whole-genome duplications and their ...
Marina Brasó-Vives, Ferdinand Marlétaz, Amina Echchiki, Federica Mantica, Rafael D. Acemel, José L. Gómez-Skarmeta, Diego A. Hartasánchez, Lorlane Le Targa, Pierre Pontarotti, Juan J. Tena, Ignacio Maeso, Hector Escriva, Manuel Irimia, Marc Robinson-Rechavi   +13 more
doaj   +1 more source

Independent large scale duplications in multiple M. tuberculosis lineages overlapping the same genomic region [PDF]

, 2012
Mycobacterium tuberculosis, the causative agent of most human tuberculosis, infects one third of the world's population and kills an estimated 1.7 million people a year. With the world-wide emergence of drug resistance, and the finding of more functional
Gagneux, Sebastian, Michael Koehrsen (185361), Bonnie B Plikaytis, van Helden, Paul D., Sisk, P., Stolte, Christian, Hung, D., Jared White, Paul D. van Helden (33594), Gey van Pittius, Nicolass C., Brian Weiner, Gagneux, Sebastien, Gomez James, Bruce Birren, Sisk, Peter, Hung, Deborah, Sloutsky Alexander, White, Jared, Robert M. Warren (185350), Nicolass C. Gey van Pittius (185359), Deborah Hung (185364), Birren, Bruce, Warren, Robert M., Peter Sisk (185362), Galagan, J., van Helden, P. D., Robert M Warren, Nicolass C Gey van Pittius, Bonnie B. Plikaytis (185356), Paul D van Helden, Megan Murray (63415), Birren Bruce, Plikaytis, Bonnie B., Weiner, Brian, Koehrsen Michael, Galagan, James E., Victor Thomas C., Warren, R. M., Sloutsky, A., Bruce Birren (18146), Weiner Brian, Birren, B., Van Pittius, Nicolaas C. Gey, Christian Stolte, Stolte Christian, Gomez, J., Posey James E., Plikaytis Bonnie B., Gagneux, S., Peter Sisk, Brian Weiner (164963), James Gomez (185343), Posey, J. E., Thomas C Victor, Michael Koehrsen, Jared White (185363), Galagan James, Weiner, B., James Gomez, Warren Robert M., Gagneux Sebastien, James Galagan (185365), Murray, M., White Jared, Gey van Pittius, N. C., Galagan, James, James E Posey, White, J., Sloutsky, Alexander, Hung Deborah, Alexander Sloutsky, Stolte, C., James Galagan, Gomez, James, Deborah Hung, Sebastien Gagneux (149824), Plikaytis, B. B., Posey, James E., Koehrsen, M., Warren, Rob, van Helden Paul D., Alexander Sloutsky (185354), Sisk Peter, Sebastien Gagneux, Murray Megan, James E. Posey (155073), Murray, Megan, Megan Murray, Koehrsen, Michael, Victor, Thomas C., Victor, T. C., Christian Stolte (2869), Gey van Pittius Nicolass C., Thomas C. Victor (185348)   +93 more
core   +2 more sources

The Impact of Whole Genome Duplication on the Evolution of the Arachnids

Integrative And Comparative Biology, 2023
Synopsis The proliferation of genomic resources for Chelicerata in the past 10 years has revealed that the evolution of chelicerate genomes is more dynamic than previously thought, with multiple waves of ancient whole genome duplications affecting separate lineages.
openaire   +2 more sources

Inference of Ancient Whole-Genome Duplications and the Evolution of Gene Duplication and Loss Rates [PDF]

Molecular Biology and Evolution, 2019
Abstract Gene tree–species tree reconciliation methods have been employed for studying ancient whole-genome duplication (WGD) events across the eukaryotic tree of life. Most approaches have relied on using maximum likelihood trees and the maximum parsimony reconciliation thereof to count duplication events on specific branches of ...
Zwaenepoel, Arthur, Van de Peer, Yves
openaire   +3 more sources

Whole Genome Duplications and Contracted Breakpoint Graphs

SIAM Journal on Computing, 2007
The genome halving problem, motivated by the whole genome duplication events in molecular evolution, was solved by El-Mabrouk and Sankoff in the pioneering paper [SIAM J. Comput., 32 (2003), pp. 754-792]. The El-Mabrouk-Sankoff algorithm is rather complex, inspiring a quest for a simpler solution.
Max A. Alekseyev, Pavel A. Pevzner
openaire   +3 more sources

A reappraisal of the phylogenetic placement of the Aquilegia whole-genome duplication [PDF]

Genome Biology, 2020
AbstractThe accurate placement of an ancient whole-genome duplication (WGD) in relation to the lineage divergence is important. Here, we re-investigated the Aquilegia coerulea WGD and found it is more likely lineage-specific rather than shared by all eudicots.
Tao Shi, Jinming Chen
openaire   +3 more sources

The shape of human gene family phylogenies [PDF]

, 2006
Background: The shape of phylogenetic trees has been used to make inferences about the evolutionary process by comparing the shapes of actual phylogenies with those expected under simple models of the speciation process. Previous studies have focused
James A Cotton, Page, R.D.M., Cotton James A, Roderic DM Page, Page Roderic DM, Cotton, J.A.   +5 more
core   +1 more source

Deterministic whole-genome amplification of single cells

, 2022
S.69-86This chapter describes a single-cell whole genome amplification method (WGA) that has been originally published under the name "Single Cell Comparative Genomic Hybridization (SCOMP)" (Klein et al., Proc Natl Acad Sci U S A 96(8):4494-4499, 1999 ...
Czyz, Zbigniew Tadeusz, Klein, Christoph A.   +1 more
core   +1 more source

Subfunctionalization versus neofunctionalization after whole-genome duplication [PDF]

Nature Genetics, 2017
The question of what is the predominant evolutionary fate of genes after duplication events has been hotly debated for decades 1,2 . Two recently published articles in Nature (Lien et al . 3 ) and Nature Genetics (Braasch
Sandve, Simen R., Rohlfs, Rori V., Hvidsten, Torgeir R.   +2 more
openaire   +3 more sources