Results 11 to 20 of about 2,879,199 (292)
Interspecific introgression mediates adaptation to whole genome duplication [PDF]
Nature Communications, 2019 Whole genome duplication (WGD) presents new challenges to the establishment of optimal allelic combinations and to the meiotic machinery. Here, the authors show that adaptive gene flow from Arabidopsis arenosa could rescue the nascent A.
Sarah Marburger +9 more
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Two rounds of whole genome duplication in the ancestral vertebrate. [PDF]
PLoS Biology, 2005 The hypothesis that the relatively large and complex vertebrate genome was created by two ancient, whole genome duplications has been hotly debated, but remains unresolved.
Paramvir Dehal, Jeffrey L Boore
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Ohno-miRNAs: miRNA pairs derived from whole-genome duplication. [PDF]
PLoS Computational BiologyTwo rounds of whole-genome duplication (WGD) occurred about 500 million years ago and played a major role in the evolution of the vertebrate genomes. Human genes derived from WGD are called "ohnologs".
Leonardo Agasso +2 more
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Inverse symmetry in complete genomes and whole-genome inverse duplication. [PDF]
PLoS ONE, 2009 The cause of symmetry is usually subtle, and its study often leads to a deeper understanding of the bearer of the symmetry. To gain insight into the dynamics driving the growth and evolution of genomes, we conducted a comprehensive study of textual ...
Sing-Guan Kong +6 more
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The collapse of gene complement following whole genome duplication [PDF]
BMC Genomics, 2010 Background Genome amplification through duplication or proliferation of transposable elements has its counterpart in genome reduction, by elimination of DNA or by gene inactivation. Whether loss is primarily due to excision of random length DNA fragments
Zhu Qian, Zheng Chunfang, Sankoff David
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Timing of whole genome duplication is associated with tumor-specific MHC-II depletion in serous ovarian cancer [PDF]
Nature CommunicationsWhole genome duplication is frequently observed in cancer, and its prevalence in our prior analysis of end-stage, homologous recombination deficient high grade serous ovarian cancer (almost 80% of samples) supports the notion that whole genome ...
Nikki L. Burdett +7 more
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Escape from preferential retention following repeated whole genome duplication in plants [PDF]
Frontiers in Plant Science, 2012 The well supported gene dosage hypothesis predicts that genes encoding proteins engaged in dose-sensitive interactions cannot be reduced back to single copies once all interacting partners are simultaneously duplicated in a whole genome duplication.
James C Schnable +3 more
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Frontiers in Genetics, 2020 Megacarpaea delavayi (Brassicaceae), a plant found the high mountains of southwest China at high altitudes (3000–4800 m), is used as a vegetable or medicine. Here, we report a draft genome for this species. The assembly genome of M.
Qiao Yang +8 more
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Novelty and Convergence in Adaptation to Whole Genome Duplication [PDF]
Molecular Biology and Evolution, 2021 AbstractWhole genome duplication (WGD) can promote adaptation but is disruptive to conserved processes, especially meiosis. Studies in Arabidopsis arenosa revealed a coordinated evolutionary response to WGD involving interacting proteins controlling meiotic crossovers, which are minimized in an autotetraploid (within-species polyploid) to avoid ...
Magdalena Bohutínská +7 more
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Evolution after Whole-Genome Duplication: Teleost MicroRNAs [PDF]
Molecular Biology and Evolution, 2021 AbstractMicroRNAs (miRNAs) are important gene expression regulators implicated in many biological processes, but we lack a global understanding of how miRNA genes evolve and contribute to developmental canalization and phenotypic diversification. Whole-genome duplication events likely provide a substrate for species divergence and phenotypic change by ...
Thomas Desvignes +4 more
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