Results 21 to 30 of about 2,879,199 (292)
ADARp150 counteracts whole genome duplication. [PDF]
Nucleic Acids ResAbstract Impaired control of the G1/S checkpoint allows initiation of DNA replication under non-permissive conditions. Unscheduled S-phase entry is associated with DNA replication stress, demanding for other checkpoints or cellular pathways to maintain proliferation.
van Gemert F +10 more
europepmc +5 more sources
The evolutionary conundrum of whole‐genome duplication [PDF]
American Journal of Botany, 2020 The European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program.
Carretero‐Paulet, Lorenzo +1 more
openaire +4 more sources
Model-Based Detection of Whole-Genome Duplications in a Phylogeny [PDF]
Molecular Biology and Evolution, 2020 Abstract Ancient whole-genome duplications (WGDs) leave signatures in comparative genomic data sets that can be harnessed to detect these events of presumed evolutionary importance. Current statistical approaches for the detection of ancient WGDs in a phylogenetic context have two main drawbacks.
Zwaenepoel, Arthur, Van de Peer, Yves
openaire +3 more sources
Metabolic Adaptation after Whole Genome Duplication [PDF]
Molecular Biology and Evolution, 2009 Whole genome duplications (WGDs) have been hypothesized to be responsible for major transitions in evolution. However, the effects of WGD and subsequent gene loss on cellular behavior and metabolism are still poorly understood. Here we develop a genome scale evolutionary model to study the dynamics of gene loss and metabolic adaptation after WGD. Using
M.J.A. van Hoek (Milan), P. Hogeweg
openaire +4 more sources
BMC Ecology and Evolution, 2021 Background The great diversity in plant genome size and chromosome number is partly due to polyploidization (i.e. genome doubling events). The differences in genome size and chromosome number among diploid plant species can be a window into the ...
J. S. Eriksson +5 more
doaj +1 more source
Forensic Applications of Whole Genome Amplification [PDF]
, 2011 Whole genome amplification (WGA) has been touted as a possible technique to augment fragment analysis of STRs in amplifying low-levels of DNA recovered from crime scenes or items.
Williams, Graham
core +3 more sources
A model for biased fractionation after whole genome duplication [PDF]
BMC Genomics, 2012 Paralog reduction, the loss of duplicate genes after whole genome duplication (WGD) is a pervasive process. Whether this loss proceeds gene by gene or through deletion of multi-gene DNA segments is controversial, as is the question of fractionation bias, namely whether one homeologous chromosome is more vulnerable to gene deletion than the other.As a ...
David Sankoff +2 more
openaire +3 more sources
GPCR genes are preferentially retained after whole genome duplication. [PDF]
PLoS ONE, 2008 One of the most interesting questions in biology is whether certain pathways have been favored during evolution, and if so, what properties could cause such a preference.
Jenia Semyonov +3 more
doaj +1 more source
Genome duplication and gene loss affect the evolution of heat shock transcription factor genes in legumes. [PDF]
PLoS ONE, 2014 Whole-genome duplication events (polyploidy events) and gene loss events have played important roles in the evolution of legumes. Here we show that the vast majority of Hsf gene duplications resulted from whole genome duplication events rather than ...
Yongxiang Lin +6 more
doaj +1 more source
Communications Biology, 2021 Wenyan Nong, Zhe Qu, Yiqian Li, Tom Barton-Owen, Annette Wong and colleagues provide genomes and small RNA transcriptomes for the mangrove horseshoe crab and the tri-spine horseshoe crab.
Wenyan Nong +25 more
doaj +1 more source