Results 21 to 30 of about 86,476 (288)

Metabolic Adaptation after Whole Genome Duplication [PDF]

Molecular Biology and Evolution, 2009
Whole genome duplications (WGDs) have been hypothesized to be responsible for major transitions in evolution. However, the effects of WGD and subsequent gene loss on cellular behavior and metabolism are still poorly understood. Here we develop a genome scale evolutionary model to study the dynamics of gene loss and metabolic adaptation after WGD. Using
M.J.A. van Hoek (Milan), P. Hogeweg
openaire   +4 more sources

A model for biased fractionation after whole genome duplication [PDF]

BMC Genomics, 2012
Paralog reduction, the loss of duplicate genes after whole genome duplication (WGD) is a pervasive process. Whether this loss proceeds gene by gene or through deletion of multi-gene DNA segments is controversial, as is the question of fractionation bias, namely whether one homeologous chromosome is more vulnerable to gene deletion than the other.As a ...
David Sankoff, Chunfang Zheng, Baoyong Wang   +2 more
openaire   +2 more sources

GPCR genes are preferentially retained after whole genome duplication. [PDF]

PLoS ONE, 2008
One of the most interesting questions in biology is whether certain pathways have been favored during evolution, and if so, what properties could cause such a preference.
Jenia Semyonov, Jae-Il Park, Chia Lin Chang, Sheau Yu Teddy Hsu   +3 more
doaj   +1 more source

Genome duplication and gene loss affect the evolution of heat shock transcription factor genes in legumes. [PDF]

PLoS ONE, 2014
Whole-genome duplication events (polyploidy events) and gene loss events have played important roles in the evolution of legumes. Here we show that the vast majority of Hsf gene duplications resulted from whole genome duplication events rather than ...
Yongxiang Lin, Ying Cheng, Jing Jin, Xiaolei Jin, Haiyang Jiang, Hanwei Yan, Beijiu Cheng   +6 more
doaj   +1 more source

Horseshoe crab genomes reveal the evolution of genes and microRNAs after three rounds of whole genome duplication

Communications Biology, 2021
Wenyan Nong, Zhe Qu, Yiqian Li, Tom Barton-Owen, Annette Wong and colleagues provide genomes and small RNA transcriptomes for the mangrove horseshoe crab and the tri-spine horseshoe crab.
Wenyan Nong, Zhe Qu, Yiqian Li, Tom Barton-Owen, Annette Y. P. Wong, Ho Yin Yip, Hoi Ting Lee, Satya Narayana, Tobias Baril, Thomas Swale, Jianquan Cao, Ting Fung Chan, Hoi Shan Kwan, Sai Ming Ngai, Gianni Panagiotou, Pei-Yuan Qian, Jian-Wen Qiu, Kevin Y. Yip, Noraznawati Ismail, Siddhartha Pati, Akbar John, Stephen S. Tobe, William G. Bendena, Siu Gin Cheung, Alexander Hayward, Jerome H. L. Hui   +25 more
doaj   +1 more source

Parallel evolution of amphioxus and vertebrate small-scale gene duplications

Genome Biology, 2022
Background Amphioxus are non-vertebrate chordates characterized by a slow morphological and molecular evolution. They share the basic chordate body-plan and genome organization with vertebrates but lack their 2R whole-genome duplications and their ...
Marina Brasó-Vives, Ferdinand Marlétaz, Amina Echchiki, Federica Mantica, Rafael D. Acemel, José L. Gómez-Skarmeta, Diego A. Hartasánchez, Lorlane Le Targa, Pierre Pontarotti, Juan J. Tena, Ignacio Maeso, Hector Escriva, Manuel Irimia, Marc Robinson-Rechavi   +13 more
doaj   +1 more source

Molecular Dating of the Teleost Whole Genome Duplication (3R) Is Compatible With the Expectations of Delayed Rediploidization [PDF]

Genome Biology and Evolution
Minbo Qi, James Clark, Edmund R R Moody   +2 more
exaly   +2 more sources

Independent large scale duplications in multiple M. tuberculosis lineages overlapping the same genomic region [PDF]

, 2012
Mycobacterium tuberculosis, the causative agent of most human tuberculosis, infects one third of the world's population and kills an estimated 1.7 million people a year. With the world-wide emergence of drug resistance, and the finding of more functional
Gagneux, Sebastian, Michael Koehrsen (185361), Bonnie B Plikaytis, van Helden, Paul D., Sisk, P., Stolte, Christian, Hung, D., Jared White, Paul D. van Helden (33594), Gey van Pittius, Nicolass C., Brian Weiner, Gagneux, Sebastien, Gomez James, Bruce Birren, Sisk, Peter, Hung, Deborah, Sloutsky Alexander, White, Jared, Robert M. Warren (185350), Nicolass C. Gey van Pittius (185359), Deborah Hung (185364), Birren, Bruce, Warren, Robert M., Peter Sisk (185362), Galagan, J., van Helden, P. D., Robert M Warren, Nicolass C Gey van Pittius, Bonnie B. Plikaytis (185356), Paul D van Helden, Megan Murray (63415), Birren Bruce, Plikaytis, Bonnie B., Weiner, Brian, Koehrsen Michael, Galagan, James E., Victor Thomas C., Warren, R. M., Sloutsky, A., Bruce Birren (18146), Weiner Brian, Birren, B., Van Pittius, Nicolaas C. Gey, Christian Stolte, Stolte Christian, Gomez, J., Posey James E., Plikaytis Bonnie B., Gagneux, S., Peter Sisk, Brian Weiner (164963), James Gomez (185343), Posey, J. E., Thomas C Victor, Michael Koehrsen, Jared White (185363), Galagan James, Weiner, B., James Gomez, Warren Robert M., Gagneux Sebastien, James Galagan (185365), Murray, M., White Jared, Gey van Pittius, N. C., Galagan, James, James E Posey, White, J., Sloutsky, Alexander, Hung Deborah, Alexander Sloutsky, Stolte, C., James Galagan, Gomez, James, Deborah Hung, Sebastien Gagneux (149824), Plikaytis, B. B., Posey, James E., Koehrsen, M., Warren, Rob, van Helden Paul D., Alexander Sloutsky (185354), Sisk Peter, Sebastien Gagneux, Murray Megan, James E. Posey (155073), Murray, Megan, Megan Murray, Koehrsen, Michael, Victor, Thomas C., Victor, T. C., Christian Stolte (2869), Gey van Pittius Nicolass C., Thomas C. Victor (185348)   +93 more
core   +1 more source

Genomic plasticity enables phenotypic variation of Pseudomonas syringae pv. tomato DC3000. [PDF]

PLoS ONE, 2014
Whole genome sequencing revealed the presence of a genomic anomaly in the region of 4.7 to 4.9 Mb of the Pseudomonas syringae pv. tomato (Pst) DC3000 genome.
Zhongmeng Bao, Paul V Stodghill, Christopher R Myers, Hanh Lam, Hai-Lei Wei, Suma Chakravarthy, Brian H Kvitko, Alan Collmer, Samuel W Cartinhour, Peter Schweitzer, Bryan Swingle   +10 more
doaj   +1 more source

Profiling of gene duplication patterns of sequenced teleost genomes: evidence for rapid lineage-specific genome expansion mediated by recent tandem duplications

BMC Genomics, 2012
Background Gene duplication has had a major impact on genome evolution. Localized (or tandem) duplication resulting from unequal crossing over and whole genome duplication are believed to be the two dominant mechanisms contributing to vertebrate genome ...
Lu Jianguo, Peatman Eric, Tang Haibao, Lewis Joshua, Liu Zhanjiang   +4 more
doaj   +1 more source