Results 91 to 100 of about 778,579 (363)

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

open access: yesMolecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

Wind shear modeling for aircraft hazard definition [PDF]

open access: yes
Mathematical models of wind profiles were developed for use in fast time and manned flight simulation studies aimed at defining and eliminating these wind shear hazards.
Camp, D. W., Frost, W., Wang, S. T.
core   +1 more source

Development of a Rooftop Collaborative Experimental Space through Experiential Learning Projects [PDF]

open access: yes, 2019
The Solar, Water, Energy, and Thermal Laboratory (SWEAT Lab) is a rooftop experimental space at the University of Texas at Austin built by graduate and undergraduate students in the Cockrell School of Engineering.
Edrey, Yuval   +4 more
core   +1 more source

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

open access: yesMolecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi   +5 more
wiley   +1 more source

Creating wind field time-series over the Southern Baltic area using a dynamical downscaling approach

open access: yesMeteorologische Zeitschrift, 2013
The aim of the research is to explore the possibility of using the Weather Research and Forecasting Model 3.2.1 (WRF) for creating synthetic wind speed time-series in the southern part of the Baltic Sea.
Bartosz Czernecki
doaj   +1 more source

Sensitivity analysis of the space shuttle to ascent wind profiles [PDF]

open access: yes
A parametric sensitivity analysis of the space shuttle ascent flight to the wind profile is presented. Engineering systems parameters are obtained by flight simulations using wind profile models and samples of detailed (Jimsphere) wind profile ...
Austin, L. D., Jr., Smith, O. E.
core   +1 more source

Design features of the upcoming Coastal and Ocean Basin in Ostend, Belgium, for marine renewable energy applications [PDF]

open access: yes, 2017
The new Coastal and Ocean Basin (COB) located at the Greenbridge Science Park in Ostend, Belgium is under construction since February 2017. The laboratory will provide a versatile facility that will make a wide range of physical modelling studies ...
Troch, Peter   +13 more
core   +1 more source

Multiplex single‐cell profiling of putative cancer stem cell markers ALDH1, SOX9, SOX2, CD44, CD133 and CD15 in endometrial cancer

open access: yesMolecular Oncology, EarlyView.
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien   +7 more
wiley   +1 more source

Safety considerations in the design and operation of large wind turbines [PDF]

open access: yes
The engineering and safety techniques used to assure the reliable and safe operation of large wind turbine generators utilizing the Mod 2 Wind Turbine System Program as an example is described.
Reilly, D. H.
core   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

open access: yesMolecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park   +6 more
wiley   +1 more source

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