Results 81 to 90 of about 102,683 (311)
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Examination of wind speed based on field measurements on a low-rise building
Frontiers in Built EnvironmentMean and peak wind speeds, as well as gust factors, integral scales, and intensity of turbulence values, are essential in formulating wind loading standards for structures.
Shuoqi Wang +5 more
doaj +1 more source
, 2013 Presented in this paper are the results of numerical simulation of bushfire enhanced wind and its impact on buildings of various shapes. Using an extended computation domain, the velocity and pressure fields around three buildings which are exposed to ...
Kwok, Kenny C. S. (R14040) +4 more
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Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Computation, 2015 The motivation of this work is to bridge the gap between experimental approaches in wind tunnel testing and numerical computations, in the field of structural design against strong winds.
Julien Berthaut-Gerentes +1 more
doaj +1 more source
Effects of wind-induced tall building vibrations on human motor performance
, 2013 Prolonged exposure to wind-induced vibrations in tall buildings can cause discomfort, impair task performance, and even trigger motion sickness symptoms.
Hau, Chui Luen Vera +3 more
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Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Coupled Finite Volume and Finite Element Method Analysis of a Complex Large-Span Roof Structure
International Journal of Applied Mechanics and Engineering, 2017 The main goal of this paper is to present coupled Computational Fluid Dynamics and structural analysis for the precise determination of wind impact on internal forces and deformations of structural elements of a longspan roof structure. The Finite Volume
J. Szafran, K. Juszczyk, M. Kamiński
doaj +1 more source
The occupant response to wind-induced tall building motion in New Zealand
, 2013 1014 central business district workers in Wellington New Zealand were surveyed about wind-induced building motion. 41.7% reported wind-induced building motion.
Walton, Darren +2 more
core
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source