Morris Water Maze Learning in Two Rat Strains Increases the Expression of the Polysialylated Form of the Neural Cell Adhesion Molecule in the Dentate Gyrus But Has No Effect on Hippocampal Neurogenesis [PDF]
, 2005 In the current study, the authors investigated whether Morris water maze learning induces alterations in hippocampal neurogenesis or neural cell adhesion molecule (NCAM) polysialylation in the dentate gyrus.
Borght, Karin van der, +4 more
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Patologìâ, 2019 The aim was to determine the features of the NO system status in the left ventricular myocardium in the rats with intermittent hypoxic hypobaric hypoxia during 15 and 60 days. Material and methods.
Yu. M. Kolesnyk +2 more
doaj +1 more source
Effect of methylphenidate treatment during adolescence on norepinephrine transporter function in orbitofrontal cortex in a rat model of attention deficit hyperactivity disorder [PDF]
, 2015 Attention deficit hyperactivity disorder (ADHD) is associated with hypofunctional medial prefrontal cortex (mPFC) and orbitofrontal cortex (OFC). Methylphenidate (MPH) remediates ADHD, in part, by inhibiting the norepinephrine transporter (NET). MPH also
Dwoskin, Linda P. +2 more
core +4 more sources
Human Vaccines & Immunotherapeutics, 2020 Significant concerns have arisen over the past 3 y from the increased global spread of the mosquito-borne flavivirus, Zika. Accompanying this spread has been an increase in cases of the devastating birth defect microcephaly as well as of Guillain–Barré ...
Hyeree Choi +16 more
doaj +1 more source
Stevia preferences in Wistar rats
Psicothema, 2016 The Stevia rebaudiana plant is likely to become a major source of high-potency sweetener for the growing natural-food market. S. rebaudiana is the source of a number of sweet diterpenoid glycosides, but the major sweet constituents are rebaudioside A and stevioside.
Núñez Martínez, Paula +2 more
openaire +5 more sources
An overview of anti-diabetic plants used in Gabon: Pharmacology and Toxicology [PDF]
, 2018 © 2017 Elsevier B.V. All rights reserved.Ethnopharmacological relevance: The management of diabetes mellitus management in African communities, especially in Gabon, is not well established as more than 60% of population rely on traditional treatments as ...
A. Souza +374 more
core +4 more sources
Structural and functional analysis of the human POT1-TPP1 telomeric complex
Nature Communications, 2017 POT1 and TTP1 are part of the shelterin complex that caps and stabilizes the ends of telomeres. Here the authors present a structural analysis of the human POT1-TTP1 complex, shedding light on how it assembles and how cancer-associated mutations impact ...
Cory Rice +8 more
doaj +1 more source
Epigenetic specifications of host chromosome docking sites for latent Epstein-Barr virus
Nature Communications, 2020 Epstein-Barr virus (EBV) episomes tether to the host chromosome via EBNA1. Here, using circular chromosome conformation capture (4C), Kim et al. identify attachment sites and show that EBV episomes preferentially associate with transcriptionally silenced
Kyoung-Dong Kim +8 more
doaj +1 more source
Spontaneous Cholangiofibrosis in a Wistar Rat [PDF]
Toxicologic Pathology, 2019 In a 2-year carcinogenicity study, we identified a spontaneous cholangiofibrosis in a control male Wistar rat. This lesion has long been considered as a compound-related change, with no spontaneous cases reported in the Wistar rat. In addition to routine hematoxylin and eosin stains evaluation, we applied Masson’s trichrome staining, Alcian blue ...
Tao Chen +3 more
openaire +2 more sources
CTCF driven TERRA transcription facilitates completion of telomere DNA replication
Nature Communications, 2017 TERRA RNA is involved in maintaining stability during telomere repeat replication. Here the authors, by using CRISPR/Cas9, mutate CTCF-binding sites at start site of TERRA transcripts and find that subtelomeric CTCF facilitates telomeric DNA replication ...
Kate Beishline +5 more
doaj +1 more source