Results 41 to 50 of about 261,546 (213)

Journal of comparative neurology

, 1911
Title from cover.Vol. 65, Dec. 1936, called G. Carl Huber memorial volume.Mode of access: Internet.Digitized and made available by Wiley InterScience.Published by The Wistar institute of anatomy and ...
Wistar Institute of Anatomy and Biology.
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Histone variant H2A.Z cooperates with EBNA1 to maintain Epstein-Barr virus latent epigenome

mBio
Chromatin structure plays a central role in the regulation of Epstein-Barr virus (EBV) latency. The histone variant H2A.Z.1 has been implicated in chromatin structures associated with the initiation of transcription and DNA replication.
Leonardo Josué Castro-Muñoz, Davide Maestri, Leena Yoon, Bhanu Chandra Karisetty, Italo Tempera, Paul Lieberman   +5 more
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The three-dimensional structure of Epstein-Barr virus genome varies by latency type and is regulated by PARP1 enzymatic activity

Nature Communications, 2022
Genome folding in the nucleus plays an important role in regulating gene expression. Here the authors show that 3D genome architecture also plays an important role for gene expression adaptability for the Epstein-Barr Virus (EBV), a virus that is ...
Sarah M. Morgan, Hideki Tanizawa, Lisa Beatrice Caruso, Michael Hulse, Andrew Kossenkov, Jozef Madzo, Kelsey Keith, Yinfei Tan, Sarah Boyle, Paul M. Lieberman, Italo Tempera   +10 more
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EBNA1 inhibitors reveal CDC7 and POU2F1 as direct functional targets in EBV epithelial cancers

mBio
Epstein-Barr virus (EBV) latent infection is causally linked to several epithelial cancers, including endemic forms of undifferentiated nasopharyngeal carcinoma (NPC), and to a subtype of gastric cancer (GC).
Songtao He, Niseno Terhuja, Samantha S. Soldan, Christopher Chen, Joel Cassel, Xiangfan Yin, Qin Liu, Sun Sook Chung, Leonardo Josué Castro-Muñoz, Leena Yoon, Jie Wang, Joseph M. Salvino, Benjamin E. Gewurz, Italo Tempera, Troy E. Messick, Paul M. Lieberman   +15 more
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Effect of Wheat/Cassava Composite Bread on Liver Architecture of Wistar Rat

, 2018
This study reports the effect of different levels of wheat/cassava composite flour on liver architecture of wistar rat. The cassava variety- TMS 98/419 and Twenty (20) male wistar rats were used for the study.
MO Odo, F. Azi, M.O. Odo, PA Okorie, V.N. Nwobasi, P.A. Okorie, F Azi, VN Nwobasi   +7 more
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Agranulocytosis leads to intestinal Echinococcus multilocularis oncosphere invasion and hepatic metacestode development in naturally resistant Wistar rats.

, 2021
Susceptibility to Echinococcus multilocularis infection considerably varies among intermediate (mostly rodents) and dead-end host species (e.g. humans and pig), in particular regarding intestinal oncosphere invasion and subsequent hepatic metacestode ...
Kronenberg, Philipp A, Nur, Selim, LeibundGut-Landmann, Salomé, Deplazes, Peter, Monné Rodriguez, Josep, Joekel, Deborah E, Kipar, Anja   +6 more
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Clonal dynamics shaped by diverse drug-tolerant persister states in melanoma resistance

Molecular Cancer
Background Most advanced melanomas initially respond to targeted therapy but eventually relapse. Increasing evidence suggests that drug-tolerant persister cells can adopt a reversible drug-refractory state and represent a key driver of therapeutic ...
Haiyin Li, Yeqing Chen, Jessica Kaster, Maggie Dunne, Min Xiao, Ling Li, Monzy Thomas, Nazifa Promi, Dylan Fingerman, Gregory Schuyler Brown, Qiuxian Zheng, Xingyue Zhu, McKenna Reale, Andrew Patterson, Le Gao, Xuxiang Zhang, Siqi Jiang, Tianxing Hu, Hanzhang Fang, Jianlan Ren, Cong Qi, Luyang Wang, Haiwei Mou, Gatha Thacker, Eric Ramirez Salazar, Jessie Villanueva, Arjun Raj, Dave SB Hoon, Tian Bin, Jozef Madzo, Zhi Wei, Noam Auslander, Meenhard Herlyn   +32 more
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Impact of Nanochitin on Serum Concentration of Iron and Calcium in Wistar Rats

Medical Laboratory Journal, 2022
Background and objectives: Considering the increasing use of nanochitin for the removal of heavy metals from aqueous solutions, examining the biological effects of this substance on the level of essential metals for humans and animals is crucial ...
Negin Valizadeh KeshmeshTapeh, Somayeh Namroodi, Shohreh Taziki   +2 more
doaj  

Suppression of Nucleotide Metabolism Underlies the Establishment and Maintenance of Oncogene-Induced Senescence

Cell Reports, 2013
Oncogene-induced senescence is characterized by a stable cell growth arrest, thus providing a tumor suppression mechanism. However, the underlying mechanisms for this phenomenon remain unknown.
Katherine M. Aird, Gao Zhang, Hua Li, Zhigang Tu, Benjamin G. Bitler, Azat Garipov, Hong Wu, Zhi Wei, Stephan N. Wagner, Meenhard Herlyn, Rugang Zhang   +10 more
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Non-invasive plasma glycomic and metabolic biomarkers of post-treatment control of HIV

Nature Communications, 2021
Current HIV cure-focused clinical trials rely on analytic treatment interruption (ATI) to evaluate post-treatment control (PTC). Here, combining untargetted metabolomics and glycomics in two HIV clinical cohorts, in vitro assays, and machine learning ...
Leila B. Giron, Clovis S. Palmer, Qin Liu, Xiangfan Yin, Emmanouil Papasavvas, Radwa Sharaf, Behzad Etemad, Mohammad Damra, Aaron R. Goldman, Hsin-Yao Tang, Rowena Johnston, Karam Mounzer, Jay R. Kostman, Pablo Tebas, Alan Landay, Luis J. Montaner, Jeffrey M. Jacobson, Jonathan Z. Li, Mohamed Abdel-Mohsen   +18 more
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