Results 31 to 40 of about 261,546 (213)

Low-carbohydrate diets affect energy balance and fuel homeostasis differentially in lean and obese rats [PDF]

, 2006
In parallel with increased prevalence of overweight people in affluent societies are individuals trying to lose weight, often using low-carbohydrate diets.
van Dijk, G., Dijk, G. van,, Morens, C., Morens, C.,, Scheurink, A.J.W.,, G. van Dijk, C. Morens, Sirot, V.,, Scheurink, A. J. W., V. Sirot, A. J. W. Scheurink, van Dijk, G.; id_orcid, Sirot, V.   +12 more
core   +1 more source

The features of the nitric oxide system in the left ventricle myocardium in the rats with experimental intermittent hypoxia of different duration

Patologìâ, 2019
The aim was to determine the features of the NO system status in the left ventricular myocardium in the rats with intermittent hypoxic hypobaric hypoxia during 15 and 60 days. Material and methods.
Yu. M. Kolesnyk, M. I. Isachenko, O. V. Melnikova   +2 more
doaj   +1 more source

Telomeres and Viruses: Common Themes of Genome Maintenance

Frontiers in Oncology, 2012
Genome maintenance mechanisms actively suppress genetic instability associated with cancer and aging. Some viruses provoke genetic instability by subverting the host’s control of genome maintenance.
Zhong eDeng, Zhuo eWang, Paul M Lieberman   +2 more
doaj   +1 more source

Pol α-primase dependent nuclear localization of the mammalian CST complex

Communications Biology, 2021
Kelich, Papaioannou and Skordalakes investigate the intracellular localization dynamics of the mammalian CST, a protein complex critical for telomere maintenance and homeostasis.
Joseph M. Kelich, Harry Papaioannou, Emmanuel Skordalakes   +2 more
doaj   +1 more source

Spontaneous Cholangiofibrosis in a Wistar Rat [PDF]

Toxicologic Pathology, 2019
In a 2-year carcinogenicity study, we identified a spontaneous cholangiofibrosis in a control male Wistar rat. This lesion has long been considered as a compound-related change, with no spontaneous cases reported in the Wistar rat. In addition to routine hematoxylin and eosin stains evaluation, we applied Masson’s trichrome staining, Alcian blue ...
Tao Chen, Ke Chen, Shaung Qiu, Peter C. Mann   +3 more
openaire   +2 more sources

Basic values of M-mode echocardiographic parameters of the left ventricle in outbreed Wistar rats

Veterinární Medicína, 2012
This paper describes the partial results of an echocardiographic study in sixty outbreed Wistar rats. Animals of parity sex ratio were chosen for the experiment.
P. Scheer, V. Sverakova, J. Doubek, K. Janeckova, I. Uhrikova, P. Svoboda   +5 more
doaj   +1 more source

Topoisomerase 1 cleavage complex enables pattern recognition and inflammation during senescence

Nature Communications, 2020
Here, the authors show that the topoisomerase 1-DNA covalent cleavage complex plays a critical role in mediating cytoplasmic chromatin fragments recognition by cyclic GMP-AMP synthase during senescence.
Bo Zhao, Pingyu Liu, Takeshi Fukumoto, Timothy Nacarelli, Nail Fatkhutdinov, Shuai Wu, Jianhuang Lin, Katherine M. Aird, Hsin-Yao Tang, Qin Liu, David W. Speicher, Rugang Zhang   +11 more
doaj   +1 more source

Superficial Nephrons in BALB/c and C57BL/6 Mice Facilitate In Vivo Multiphoton Microscopy of the Kidney [PDF]

, 2013
Multiphoton microscopy (MPM) offers a unique approach for addressing both the function and structure of an organ in near-real time in the live animal. The method however is limited by the tissue-specific penetration depth of the excitation laser.
Bardehle, Sophia, Bardehle Sophia, Castrop Hayo, Castrop, Hayo, Schießl, Ina Maria, Hayo Castrop, Schießl Ina Maria, Schießl, I.M., Castrop, H., Ina Maria Schießl, Bardehle, S., Sophia Bardehle   +11 more
core   +1 more source

Induction of tier-2 neutralizing antibodies in mice with a DNA-encoded HIV envelope native like trimer

Nature Communications, 2022
HIV envelope is a target for vaccine development, but induction of broadly neutralizing antibodies has been difficult. Here, the authors show that electroporation with a synthetic DNA vaccine construct allows in vivo production of HIV envelope native ...
Ziyang Xu, Susanne Walker, Megan C. Wise, Neethu Chokkalingam, Mansi Purwar, Alan Moore, Edgar Tello-Ruiz, Yuanhan Wu, Sonali Majumdar, Kylie M. Konrath, Abhijeet Kulkarni, Nicholas J. Tursi, Faraz I. Zaidi, Emma L. Reuschel, Ishaan Patel, April Obeirne, Jianqiu Du, Katherine Schultheis, Lauren Gites, Trevor Smith, Janess Mendoza, Kate E. Broderick, Laurent Humeau, Jesper Pallesen, David B. Weiner, Daniel W. Kulp   +25 more
doaj   +1 more source

Auricular chondritis in Wistar rats [PDF]

Laboratory Animals, 1990
The macroscopic and microscopic features of auricular chondritis in Wistar rats are described. Histologic lesions are characterized by granulomatous inflammation, chondrolysis, and multinodular proliferative foci. The condition in Wistar rats is compared to auricular chondritis in other strains of rats.
B J, McEwen, N J, Barsoum
openaire   +2 more sources