Low-carbohydrate diets affect energy balance and fuel homeostasis differentially in lean and obese rats [PDF]
, 2006 In parallel with increased prevalence of overweight people in affluent societies are individuals trying to lose weight, often using low-carbohydrate diets.
van Dijk, G. +12 more
core +2 more sources
Telomeres and Viruses: Common Themes of Genome Maintenance
Frontiers in Oncology, 2012 Genome maintenance mechanisms actively suppress genetic instability associated with cancer and aging. Some viruses provoke genetic instability by subverting the host’s control of genome maintenance.
Zhong eDeng +2 more
doaj +1 more source
Pol α-primase dependent nuclear localization of the mammalian CST complex
Communications Biology, 2021 Kelich, Papaioannou and Skordalakes investigate the intracellular localization dynamics of the mammalian CST, a protein complex critical for telomere maintenance and homeostasis.
Joseph M. Kelich +2 more
doaj +1 more source
Patologìâ, 2019 The aim was to determine the features of the NO system status in the left ventricular myocardium in the rats with intermittent hypoxic hypobaric hypoxia during 15 and 60 days. Material and methods.
Yu. M. Kolesnyk +2 more
doaj +1 more source
Superficial Nephrons in BALB/c and C57BL/6 Mice Facilitate In Vivo Multiphoton Microscopy of the Kidney [PDF]
, 2013 Multiphoton microscopy (MPM) offers a unique approach for addressing both the function and structure of an organ in near-real time in the live animal. The method however is limited by the tissue-specific penetration depth of the excitation laser.
Bardehle, Sophia +11 more
core +2 more sources
Topoisomerase 1 cleavage complex enables pattern recognition and inflammation during senescence
Nature Communications, 2020 Here, the authors show that the topoisomerase 1-DNA covalent cleavage complex plays a critical role in mediating cytoplasmic chromatin fragments recognition by cyclic GMP-AMP synthase during senescence.
Bo Zhao +11 more
doaj +1 more source
Effect of soursop stem bark extract (Annona muricata L.) on pancreatic histology in alloxan-induced diabetic Wistar rats (Rattus norvegicus) [PDF]
Romanian Journal of Pharmaceutical PracticeBackground. Soursop (Annona muricata L.) is widely used as a herbal remedy, including for diabetes. Diabetes mellitus is associated with increased blood glucose levels, pancreatic beta-cell damage, and morphological changes in the islets of Langerhans ...
YUZIANI, Nadia ALKHALIFA, Juwita SAHPUTR
doaj +1 more source
Spontaneous Cholangiofibrosis in a Wistar Rat [PDF]
Toxicologic Pathology, 2019 In a 2-year carcinogenicity study, we identified a spontaneous cholangiofibrosis in a control male Wistar rat. This lesion has long been considered as a compound-related change, with no spontaneous cases reported in the Wistar rat. In addition to routine hematoxylin and eosin stains evaluation, we applied Masson’s trichrome staining, Alcian blue ...
Tao Chen +3 more
openaire +2 more sources
THE EFFECT OF TRANS FATTY ACID DIET ON BLOOD GLUCOSE LEVEL OF WISTAR RATS (A PRELIMINARY STUDY) [PDF]
, 2011 Background: Trans fatty acids are unsaturated fatty acids that contain at least one double bond in the trans configuration and formed through the process of partial hydrogenation.
Setyawati, Amallia Nuggetsiana +2 more
core +1 more source
Advanced Materials, EarlyView.A novel engineering strategy that establishes material design principles for incorporating anti‐inflammatory steroids into lipid nanoparticles to reduce LNP‐induced inflammation while retaining mRNA delivery. Results are validated in vitro and in three animal models of inflammation and autoimmunity in vivo.
Ajay S. Thatte +21 more
wiley +1 more source