Histologic sequelae following exposure to turmeric extract on wistar rats ovary and uterus
The regular and single use of turmeric in reference to the reproductive system following several review is conflicting, and its effect has not been fully ascertained.
Efe Endurance Ahama +5 more
core +2 more sources
Regenerating effect of hyaluronic acid on circumferential bone defects in Wistar albino rats.
Objective: To determine the regenerating effect of hyaluronic acid on circumferential bone defects in albino Wistar rats. Material and Methods: An experimental type study was designed and carried out with 15 albino male Wistar rats, 4 months old and ...
Cecilia Bueno-Beltrán +3 more
doaj +1 more source
ANALYSIS OF THE EFFECT OF CURCUMA LONGA ETHANOL EXTRACT AS ANTI-DYSLIPIDEMIA IN MALE WISTAR RATS [PDF]
: Dyslipidemia is a lipid metabolism disorder characterized by increased or decreased lipid fractions in plasma. It is a risk factor for diseases still an essential problem in Indonesia, such as coronary heart disease (CHD).
Wang Rui
core +1 more source
Significant concerns have arisen over the past 3 y from the increased global spread of the mosquito-borne flavivirus, Zika. Accompanying this spread has been an increase in cases of the devastating birth defect microcephaly as well as of Guillain–Barré ...
Hyeree Choi +16 more
doaj +1 more source
Structural and functional analysis of the human POT1-TPP1 telomeric complex
POT1 and TTP1 are part of the shelterin complex that caps and stabilizes the ends of telomeres. Here the authors present a structural analysis of the human POT1-TTP1 complex, shedding light on how it assembles and how cancer-associated mutations impact ...
Cory Rice +8 more
doaj +1 more source
CTCF driven TERRA transcription facilitates completion of telomere DNA replication
TERRA RNA is involved in maintaining stability during telomere repeat replication. Here the authors, by using CRISPR/Cas9, mutate CTCF-binding sites at start site of TERRA transcripts and find that subtelomeric CTCF facilitates telomeric DNA replication ...
Kate Beishline +5 more
doaj +1 more source
Targeting the IRE1α/XBP1s pathway suppresses CARM1-expressing ovarian cancer
The unfolded protein response (UPR) promotes cell survival in cancers with hyperactive ER stress response. Here the authors show that CARM1, an arginine methyltransferase, controls the IRE1α/XBP1 pathway of the UPR and the inhibition of this pathway can ...
Jianhuang Lin +13 more
doaj +1 more source
COVID-19 Severity Is Associated with Differential Antibody Fc-Mediated Innate Immune Functions
A state of hyperinflammation and increased complement activation has been associated with coronavirus disease 2019 (COVID-19) severity. However, the pathophysiological mechanisms that contribute to this phenomenon remain mostly unknown.
Opeyemi S. Adeniji +15 more
doaj +1 more source
Spontaneous Synovitis in Wistar Rats [PDF]
Spontaneous synovitis has been detected in the stifle joints of control Wistar rats in 4-wk and 2-yr toxicity studies, and a specific site was found to be predisposed to synovitis. The incidence of synovitis was 27.5% for males in the 4-wk study and 40.0% for males and 16.0% for females in the 2-yr study. The severity was not increased with aging.
S, Sasaki +4 more
openaire +2 more sources
Epigenetic specifications of host chromosome docking sites for latent Epstein-Barr virus
Epstein-Barr virus (EBV) episomes tether to the host chromosome via EBNA1. Here, using circular chromosome conformation capture (4C), Kim et al. identify attachment sites and show that EBV episomes preferentially associate with transcriptionally silenced
Kyoung-Dong Kim +8 more
doaj +1 more source

