Results 31 to 40 of about 584,417 (340)

Structural and functional analysis of the human POT1-TPP1 telomeric complex

Nature Communications, 2017
POT1 and TTP1 are part of the shelterin complex that caps and stabilizes the ends of telomeres. Here the authors present a structural analysis of the human POT1-TTP1 complex, shedding light on how it assembles and how cancer-associated mutations impact ...
Cory Rice, Prashanth Krishna Shastrula, Andrew V. Kossenkov, Robert Hills, Duncan M. Baird, Louise C. Showe, Tzanko Doukov, Susan Janicki, Emmanuel Skordalakes   +8 more
doaj   +1 more source

Epigenetic specifications of host chromosome docking sites for latent Epstein-Barr virus

Nature Communications, 2020
Epstein-Barr virus (EBV) episomes tether to the host chromosome via EBNA1. Here, using circular chromosome conformation capture (4C), Kim et al. identify attachment sites and show that EBV episomes preferentially associate with transcriptionally silenced
Kyoung-Dong Kim, Hideki Tanizawa, Alessandra De Leo, Olga Vladimirova, Andrew Kossenkov, Fang Lu, Louise C. Showe, Ken-ichi Noma, Paul M. Lieberman   +8 more
doaj   +1 more source

Oxidative stress‐mediated alterations on sperm parameters in male Wistar rats exposed to 3G mobile phone radiation

Andrologia, 2018
In recent years, there has been significant increase in mobile phone users. With this, health concerns associated with the exposure to electromagnetic radiation are also increasing.
R. Gautam, Kumari Vandana Singh, J. Nirala, Nina Nancy Murmu, Ramovatar Meena, Paulraj Rajamani   +5 more
semanticscholar   +1 more source

Spontaneous Cholangiofibrosis in a Wistar Rat [PDF]

Toxicologic Pathology, 2019
In a 2-year carcinogenicity study, we identified a spontaneous cholangiofibrosis in a control male Wistar rat. This lesion has long been considered as a compound-related change, with no spontaneous cases reported in the Wistar rat. In addition to routine hematoxylin and eosin stains evaluation, we applied Masson’s trichrome staining, Alcian blue ...
Tao Chen, Ke Chen, Shaung Qiu, Peter C. Mann   +3 more
openaire   +2 more sources

CTCF driven TERRA transcription facilitates completion of telomere DNA replication

Nature Communications, 2017
TERRA RNA is involved in maintaining stability during telomere repeat replication. Here the authors, by using CRISPR/Cas9, mutate CTCF-binding sites at start site of TERRA transcripts and find that subtelomeric CTCF facilitates telomeric DNA replication ...
Kate Beishline, Olga Vladimirova, Stephen Tutton, Zhuo Wang, Zhong Deng, Paul M. Lieberman   +5 more
doaj   +1 more source

Effect of dithiocarbamate thiram on Wistar rat growth plate and articular cartilage [PDF]

, 2012
Avaliou-se o efeito do tirame, ditiocarbamato largamente utilizado na agricultura como antifúngico e repelente de roedores, na ossificação endocondral de mamíferos, usando, como modelo, ratos Wistar.
Cabrita, AS, Capela e Silva, F, Fialho, L, Pereira, AMF, Rafael, A   +4 more
core   +3 more sources

Pol α-primase dependent nuclear localization of the mammalian CST complex

Communications Biology, 2021
Kelich, Papaioannou and Skordalakes investigate the intracellular localization dynamics of the mammalian CST, a protein complex critical for telomere maintenance and homeostasis.
Joseph M. Kelich, Harry Papaioannou, Emmanuel Skordalakes   +2 more
doaj   +1 more source

An overview of anti-diabetic plants used in Gabon: Pharmacology and Toxicology [PDF]

, 2018
© 2017 Elsevier B.V. All rights reserved.Ethnopharmacological relevance: The management of diabetes mellitus management in African communities, especially in Gabon, is not well established as more than 60% of population rely on traditional treatments as ...
A. Souza, Abdelgadir, Abdu-Aguye, Abdulrazaq, Abubakar, Adebayo, Adedoyin, Adelusi, Ademuyiwa, Adeneye, Adeneye, Adeneye, Adeneye, Aderibigbe, Adeyemi, Adisa, Adler, Agbor, Agnaniet, Agunbiabe, Agyare, Ajaiyeoba, Ajaiyoeba, Ajao, Ajayi, Akah, Akash, Akinloye, Akpanyung, Aladodo, Alaribe, Amole, Anaduaka, Anosike, Anowi, Anowi, Antia, Anyanwu, Apers, Areola, Arthur, Asadu, Asha, Ashraf, Asolkar, Assob, Asuquo, Atangwho, Atawodi, Atawodi, Aw, Awah, Awe, Aziba, B. Bading Taika, Balasubramanian, Bamisaye, Bapna, Bardi, Bayan, Bella, Ben-Chioma, Bera, Biney, Bisong, Brantley, Calapai, Campbell, Campbell-Tofte, Capasso, Chika, Chokshi, Chris-Ozoko, Coolborn, Coria-Téllez, Da-Costa-Rocha, Dadzeasah, Dahake, Das, Dhanabalan, Djeussi, Djimeli, Djomeni, Djomeni Dzeufiet, Effiong, Effiong, Effo, Eidi, Ejike, El-Demerdash, Elufioye, Elumalai, Eluwa, Eneh, Erharuyi, Erhirhie, Eteng, Etuk, Ewenighi, Ewere, Eyong, Eze, Ezeasor, Ezejindu, Ezejiofor, Ezeokeke, Ezike, Ezuruike, Fang-Chui, Farzaei, Fernand, Ferreira, Feuya Tchouya, Feuya Tchouya, Fongang, Fred-Jaiyesimi, Gandhare, Ganesh, Gbadegesin, Gboeloh, Gemede, Ghani, Ghiware, Gomez-Flores, Gondi, Goutarel, Gupta, Gutierrez, H.P. Bourobou Bourobou, Halim, Hamzah, Hansen, Helfer, Hossain, Houghton, Houël, Huang, Huang, Husain, Husin, Ibibia, Igbe, Igboasoiyi, Ilodigwe, Ilodigwe, Ilusanya, Inya-Agha, Iroanya, Irondi, Irondi, Ishola, Iwu, Iyamah, Jawonisi, Juárez-Rojop, Juárez-Rojop, Kadima, Kaiser, Kamagate, Kamboj, Karimi, Karioti, Kathirvel, Kazeem, Kazeem, Kengni, Kengni, Khodabakhsh, Kolawole, Kouakou, Koudou, Kouitcheu Mabeku, Krishna, Kubilienė, Kuete, Kuete, Kuete, Kulkarni, Kumar, Kumar, Kumar, Kupchan, L. Lione, L.S. MacKenzie, Lakshmi, Lamidi, Lawal, Lawal, Laxane, Lee, Li, Lima, Ludvik, Ludvik, Luka, M. Bouckandou, Mabeku, Madingou, Madingou, Malviya, Manga, Maniyar, Manjur, Manvitha, Mathur, Maurya, Mačiulaitis, Mbiantcha, Mebale, Mengome, Midawa, Miranda-Osorio, Mishra, Miura, Mohamed, Mohammed, Mohammed, Mohammed, Mohammed, Momoh, Montasser, Muhammad, Muhammad, Muhammad, Muhammad, Muttaka, Nabukenya, Nakavuma, Naseri, Naskar, Navghare, Ndam, Nessa, Ngoc, Ngondi, Ngondi, Ngueguim, Ngueguim, Nishimura, Niyonzima, Nkono Ya Nkono, Nkono Ya Nkono, Ntyonga-Pono, Nwamarah, Nweze, Nwodo, Nwokocha, Nyunaï, Nyunaï, N’doua, N’guessan, N’Guessan, Obiang, Obiudu, Ocho-Anin Atchibri, Oduola, Oduola, Ofusori, Ogbonnia, Ogunrinola, Ojewole, Ojewole, Ojewunmi, Ojewunmi, Ojiako, Okeke, Okokon, Okokon, Okokon, Okolie, Okolo, Okonkwo, Olajide, Olaleye, Olatokunboh, Olivier, Olowu, Olubomehin, Ombra, Omodamiro, Omonkhua, Ong, Onyekwe, Osabede, Osadebe, Osigwe, Ouédraogo, Oyewusi j, Ozsoy-Sacan, Padilla-Camberos, Palaksha, Panda, Panda, Parle, Passoni, Patel, Patil, Ping, Pochapski, Pour, Pérez, Rajesh, Raji, Rauf, Ravi, Renjith, Rong, Rosemary, Roy, Sabitha, Sagnia, Santas, Satyaprakash, Saxena, Seung, Shah, Sharma, Sharma, Sharma, Shittu, Silva, Singh, Singh, Sio, Somova, Souza, Sowemimo, Sudhakar, Sule, Sunday, Sunday, Suryawanshi, Sutar, Swargiary, Swathi, Taj Eldin, Talreja, Tan Paul, Tanayen, Tchamadeau, Teugwa, Thongsom, Titanji, Tjeck, Togola, Toma, Toma, Trabelsi, Uchechi, Ufelle, Umoh, Vannamalar, Varghese, Varghese, Vashishtha, Verma, Verma, Vijayalakshmi, Vikram, Vliet, Wang, Wang, Wauthoz, Woode, Yakubu, Yasir, Yeap, Yessoufou, Yokozawa, Yousuf, Yu, Zakiah, Zhang, Zhao, Zheng   +374 more
core   +4 more sources

Auricular chondritis in Wistar rats [PDF]

Laboratory Animals, 1990
The macroscopic and microscopic features of auricular chondritis in Wistar rats are described. Histologic lesions are characterized by granulomatous inflammation, chondrolysis, and multinodular proliferative foci. The condition in Wistar rats is compared to auricular chondritis in other strains of rats.
N. J. Barsoum, B. J. McEwen
openaire   +3 more sources

Telomeres and Viruses: Common Themes of Genome Maintenance

Frontiers in Oncology, 2012
Genome maintenance mechanisms actively suppress genetic instability associated with cancer and aging. Some viruses provoke genetic instability by subverting the host’s control of genome maintenance.
Zhong eDeng, Zhuo eWang, Paul M Lieberman   +2 more
doaj   +1 more source