Results 61 to 70 of about 427,006 (340)

UV Laser‐Induced Carbon Microelectrode Arrays for Neuronal Recordings

Advanced Healthcare Materials, EarlyView.
Thin‐film electrodes are flexible devices of high conformability and minimal dimensions with attractive properties for in vivo and in vitro bioelectronics. Here, electrodes are developed from parylene films via ultraviolet laser‐induced carbonization.
Fulvia Del Duca, Koji Sakai, Beatrice De Chiara, Toichiro Goto, Defne Tüzün, Lukas Hiendlmeier, George Al Boustani, Hu Peng, Tetsuhiko F. Teshima, Simon N. Jacob, Bernhard Wolfrum   +10 more
wiley   +1 more source

Impact of Nanochitin on Serum Concentration of Iron and Calcium in Wistar Rats

Medical Laboratory Journal, 2022
Background and objectives: Considering the increasing use of nanochitin for the removal of heavy metals from aqueous solutions, examining the biological effects of this substance on the level of essential metals for humans and animals is crucial ...
Negin Valizadeh KeshmeshTapeh, Somayeh Namroodi, Shohreh Taziki   +2 more
doaj  

Treatment with the PPARα agonist fenofibrate improves the efficacy of CD8+ T cell therapy for melanoma

Molecular Therapy: Oncolytics, 2023
Adoptive transfer of tumor antigen-specific CD8+ T cells can limit tumor progression but is hampered by the T cells’ rapid functional impairment within the tumor microenvironment (TME). This is in part caused by metabolic stress due to lack of oxygen and
Mohadeseh Hasanpourghadi, Arezki Chekaoui, Sophia Kurian, Raj Kurupati, Robert Ambrose, Wynetta Giles-Davis, Amara Saha, Xu Xiaowei, Hildegund C.J. Ertl   +8 more
doaj   +1 more source

Strain differences in the expression of dopamine D1 receptors in Wistar–Kyoto (WKY) and Wistar rats [PDF]

Life Sciences, 2008
The Wistar-Kyoto (WKY) rat is a stress-sensitive strain that is prone to depressive-like behavior in various experimental paradigms. While recent work has highlighted a role for dopamine (DA) in the pathology of depression, research on the WKY rat has also suggested that dysfunction of DA pathways may be an important component of the behavior in this ...
Shanaz Tejani-Butt, Irene Yaroslavsky, Andrew M. Novick   +2 more
openaire   +3 more sources

Injectable Deep Eutectic Solvent‐Based Ionic Gel With Rapid Gelation and Broad Hemostatic Functionality

Advanced Healthcare Materials, EarlyView.
An injectable deep eutectic solvent‐based ionic gel is developed for rapid in situ gelation and broad‐spectrum hemostatic functionality. The material combines high mechanical strength, strong tissue adhesion, and antibacterial activity, demonstrating potential as an advanced biofunctional gel for emergency bleeding control and wound care.
Jia‐Yu Yang, En‐Yu Zhou, Ting‐Hui Cheng, Pin‐Hung Liu, Wen‐Ching Hsieh, Hui‐Ching Cheng, Yi‐Kai Hong, Yu‐Chen Lin, Yi‐Chiung Hsu, Chao‐Chun Yang, Chao‐Kai Hsu, Li‐Chieh Kuo, Shang‐Chin Hsieh, Cheng‐Hsin Chuang   +13 more
wiley   +1 more source

Biocompatible PVDF Nanofibers with Embedded Magnetite Nanodiscs Enable Wireless Magnetoelectric Stimulation in Premotor Cortex

Advanced Healthcare Materials, EarlyView.
Flexible, biocompatible PVDF nanofibers embedded with magnetite nanodiscs enable wireless magnetoelectric neuromodulation. Shape anisotropy of the nanodiscs facilitates magnetostrictive strain transfer under alternating magnetic fields, allowing activation of neurons in vitro and behavioral modulation in vivo, without requiring rigid implants or ...
Lorenzo Signorelli, Anouk Wolters, Vicente Durán Toro, Jonas Englhard, Mahdieh Shojaei Baghini, Elif Koçar, Franziska Wasner, Nadine I. Goldenstein, Hadi Heidari, Julien Bachmann, Sarah Hescham, Danijela Gregurec   +11 more
wiley   +1 more source

Can Viruses be Modified to Achieve Sustained Gene Transfer?

Frontiers in Microbiology, 2011
It is very easy to replace a faulty gene in an immunocompromised mouse. First, one takes a well-characterized virus, such as an adenovirus or an adeno-associated virus, and incorporates the correct version of the faulty gene together with some regulatory
Hildegund CJ Ertl, Hua eLi
doaj   +1 more source

Phospholipid Metabolism Is Associated with Time to HIV Rebound upon Treatment Interruption

mBio, 2021
The likelihood of HIV rebound after stopping antiretroviral therapy (ART) is a combination of the size of HIV reservoirs that persist despite ART and the host immunological and inflammatory factors that control these reservoirs.
Leila B. Giron, Emmanouil Papasavvas, Xiangfan Yin, Aaron R. Goldman, Hsin-Yao Tang, Clovis S. Palmer, Alan L. Landay, Jonathan Z. Li, John R. Koethe, Karam Mounzer, Jay R. Kostman, Qin Liu, Luis J. Montaner, Mohamed Abdel-Mohsen   +13 more
doaj   +1 more source

Localisation of the melanocortin-2-receptor and its accessory proteins in the developing and adult adrenal gland [PDF]

, 2011
The melanocortin-2-receptor (MC2R)/MC2R accessory protein (MRAP) complex is critical to the production of glucocorticoids from the adrenal cortex. Inactivating mutations in either MC2R or MRAP result in the clinical condition familial glucocorticoid ...
Chan, LF, Clark, AJ, Gorrigan, RJ, Guasti, L, King, P   +4 more
core   +2 more sources

A Hydrophilic Hollow Microneedle Platform for Sampling Interstitial Fluid and On‐Site Biomarker Detection

Advanced Materials Technologies, EarlyView.
This study presents a superhydrophilic 3D‐printed hollow microneedle patch for continuous interstitial fluid (ISF) extraction and on‐patch biomarker sensing. Combining projection micro‐stereolithography and chemical vapor deposition, high‐resolution microneedles with enhanced wettability are fabricated, enabling passive ISF uptake without external ...
Taher Abbasiasl, Sevgi Sarıca, Umut Can Yener, Emel Yilgor, Iskender Yilgor, Hatice Ceylan Koydemir, Ece Öztürk, Levent Beker   +7 more
wiley   +1 more source