Machine Learning Guided Design of Nerve‐On‐A‐Chip Platforms with Promoted Neurite Outgrowth
Compared to labor‐intensive trial‐and‐error experimentation, a machine learning (ML)‐guided workflow, incorporating cell viability assays, data augmentation, ensemble modeling, and model interpretation, is developed to accelerate nerve‐on‐a‐chip optimization and uncover data‐driven design principles.
Tsai‐Chun Chung+8 more
wiley +1 more source
Basic values of M-mode echocardiographic parameters of the left ventricle in outbreed Wistar rats
This paper describes the partial results of an echocardiographic study in sixty outbreed Wistar rats. Animals of parity sex ratio were chosen for the experiment.
P. Scheer+5 more
doaj +1 more source
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth+2 more
wiley +1 more source
OBJECTIVE: To evaluate the functional and histological effects of ganglioside G(M1) and erythropoietin after experimental spinal cord contusion injury.
Raphael Martus Marcon+4 more
doaj +1 more source
Three-Dimensional Chromatin Structure of the EBV Genome: A Crucial Factor in Viral Infection
Epstein–Barr Virus (EBV) is a human gamma-herpesvirus that is widespread worldwide. To this day, about 200,000 cancer cases per year are attributed to EBV infection. EBV is capable of infecting both B cells and epithelial cells.
Lisa Beatrice Caruso+2 more
doaj +1 more source
Protective effect of leukotriene receptor antagonist montelukast on smoking-induced lung injury in Wistar rats. [PDF]
Increased activation of alveolar macrophage, neutrophil and mast cell has been proven in cigarette smoking (CS)-related lung disorders (CSLD). An increased production of cysteinyl-leukotrienes (LTs), which are mediators secreted from the mentioned cells,
Coskun, Senol+3 more
core +1 more source
This study presents a novel implantable drug delivery systemwith a biodegradable poly(caprolactone) membrane and compressed drug core forsustained release. These implantable devices deliver risperidone in vitro for 170 days and in vivo for 49 days in rats, showing promise for chronic conditions like schizophrenia.
Linlin Li+9 more
wiley +1 more source
IL-33 delays metastatic peritoneal cancer progression inducing an allergic microenvironment
Ovarian cancer is frequently diagnosed as peritoneal carcinomatosis. Unlike other tumor locations, the peritoneal cavity is commonly exposed to gut-breaching and ascending genital microorganisms and has a unique immune environment.
Alfredo Perales-Puchalt+10 more
doaj +1 more source
Gastroparesis and lipid metabolism-associated dysbiosis in Wistar-Kyoto rats
This study reveals that the stress-prone Wistar-Kyoto rat strain has a baseline physiology of gastroparesis and rapid small intestine transit, together with metabolic changes consistent with lipid metabolism-associated dysbiosis, compared with nonstress ...
J. Dalziel+6 more
semanticscholar +1 more source
Persistent papillary membrane in Wistar laboratory rats ( Rattus Norvegicus, Albinus Variation, Wistar ) [PDF]
ABSTRACT: The aim of this research was to evaluate the presence of persistent pupillary membrane (PPM) in rats. Thirty rats between three and four months of age and weighing 300-500 grams, provided by the biothery section of the General Administration at Universidade Estadual Paulista (UNESP), Botucatu, SP, Brazil, were subjected to ophthalmological ...
Chacaltana, Flor Diana Yokoay Claros+5 more
openaire +4 more sources