Results 91 to 100 of about 171,182 (259)

Efficacy and Safety of Subcutaneous Anifrolumab in Systemic Lupus Erythematosus: A Randomized, Phase 3 Study

Arthritis &Rheumatology, EarlyView.
Objective The multinational, phase 3, double‐blind, placebo‐controlled TULIP‐SC trial evaluated the efficacy and safety of subcutaneous anifrolumab in adults who have moderate to severe systemic lupus erythematosus (SLE) activity, despite receiving standard therapy. Methods Adults with SLE received subcutaneous anifrolumab 120 mg or placebo once weekly
Susan Manzi, Ian N. Bruce, Eric F. Morand, Richard Furie, Yoshiya Tanaka, Kenneth C. Kalunian, Anca Askanase, Patricia Puzio, Emon Khan, Jenny Wissmar, Michael Song, Catharina Lindholm, for the TULIP‐SC investigators   +12 more
wiley   +1 more source

Microinjection of Orexin-A into the Locus Coeruleus Area Induces Morphine Withdrawal Behaviors in Morphine Independent Rats

Research on Addiction, 2012
Introduction: Orexin neuropeptide has a role in opioid withdrawal behaviors. Orexin-expressing neurons that are present in the hypothalamic nuclei send dense projections to the Locus Coeruleus (LC).
Hosin Azizi, Atefeh Hadian, Saeed Semnanian   +2 more
doaj  

Withdrawal Syndromes

Journal of the Royal College of Physicians of London, 1987
I A, Liappas, F A, Jenner, B, Vicente
openaire   +2 more sources

Dual Portal Closure of Periportal Capsulotomy for Hip Arthroscopy

Arthroscopy Techniques, EarlyView.
Abstract Capsular management in hip arthroscopy is an area of ongoing research, where ease of access to the hip joint is balanced with the preservation of capsular integrity and stability. Traditional techniques such as interportal and T capsulotomies allow broad exposure but may increase the risk of postoperative instability or microinstability if not
Benjamin Lurie, Joseph M. Sliepka, Nyaluma N. Wagala, Alan L. Zhang   +3 more
wiley   +1 more source

Profound Opioid and Medetomidine Withdrawal: A Case Series and Narrative Review of Available Literature

Psychoactives
Medetomidine, a potent central acting α2 agonist, has emerged as a fentanyl adulterant in the non-medical opioid supply. Its use has been linked to a novel withdrawal syndrome that is often resistant to conventional treatment protocols.
Phil Durney, Elise Paquin, Gamal Fitzpatrick, Drew Lockstein, TaReva Warrick-Stone, Maeve Montesi, Sejal H. Patel-Francis, Jamal Rashid, Oluwarotimi Vaughan-Ogunlusi, Kelly Goodsell, Jennifer L. Kahoud, Christopher Martin, Keira Chism, Paul Goebel, Karen Alexander, Dennis Goodstein, Kory S. London   +16 more
doaj   +1 more source

Emotion Dysregulation Predicts Impairments in Peer Interaction and Adaptive Functioning in Autistic Kindergartners

Autism Research, EarlyView.
ABSTRACT Emotion Dysregulation (ED) refers to difficulties in using adaptive strategies to modulate and express emotional arousal in socially appropriate ways. While ED contributes to developmental trajectories including peer engagement, academic achievement, and mental health in neurotypical children, its impact on autistic children is unclear.
Yeseul Shin, Deanna Swain, Jeongjin Kim, Seok‐Jun Hong, Catherine Lord, So Hyun Kim   +5 more
wiley   +1 more source

Attenuation of Morphine Withdrawal Syndrome by Various Dosages of Curcumin in Comparison with Clonidine in Mouse: Possible Mechanism

Iranian Journal of Medical Sciences, 2015
Background: Herbal medical compounds and their major constituent have been used in the management and treatment of opioid withdrawal syndrome and pain.
Majid Motaghinejad, Mohammad Yasan Bangash, Pantea Hosseini, Seyed Morteza Karimian, Ozra Motaghinejad   +4 more
doaj  

Post-operative Analgesia in Opioid Dependent Patients: Comparison of ‎Intravenous Morphine and Sublingual Buprenorphine [PDF]

Addiction and Health, 2015
Background: Acute and chronic pain is prevalent in patients with opioid dependence. Lack of knowledge concerning the complex relationship between pain, opioid use, and withdrawal syndrome can account for the barriers encountered for pain management. This
Shaabanali Alizadeh, Ghafar‏ ‏Ali Mahmoudi, Hassan Solhi, Bahman Sadeghi-Sedeh, Reza Behzadi, Amir Mohammad Kazemifar   +5 more
doaj  

Autistic Children With Speech Onset Delay Show Reversed Bias in Spectral Versus Temporal Auditory Processing

Autism Research, EarlyView.
ABSTRACT A recent “hierarchical” reinterpretation of the neurological basis of autism suggests that in autism with early language delay, perceptual processing may be favored over the integration of transmodal information. This model is largely based on neuroimaging findings relating to visual processing, but predicts a corresponding reorganization in ...
Luodi Yu, Shuyu Xie, Li Wang, Laurent Mottron   +3 more
wiley   +1 more source

Associations Between Comorbidities, Developmental Status, and Disease Severity in Children With Autism Spectrum Disorder: A Multicenter Cross‐Sectional Study in China

Autism Research, EarlyView.
ABSTRACT Children with autism spectrum disorder (ASD) frequently present with co‐occurring conditions that can influence autism symptom severity and complicate clinical management. However, studies with clinician‐confirmed diagnoses in non‐Western populations remain limited.
Dizhou Pang, Guiqin Duan, Qing Shang, Huichun Zhang, Binbin Wang, Huaili Ding, Huihui Kang, Yue Zhao, Yuxia Lu, Gai Tian, Li Zhang, Wu Jiang, Ganyu Wang, Cailing Liang, Lingling Zhang, Bingbing Li, Zhenghua Li, Chunlan Song, Yanyan Yang, Yazhe Wang, Kaichen Yue, Yongbin Lang, Jiatian Liu, Xiaoli Zhang, Yiran Xu, Changlian Zhu   +25 more
wiley   +1 more source