Results 81 to 90 of about 1,289,348 (247)

Outpatient alcohol detoxification: Implementation efficacy and outcome effectiveness of a model project [PDF]

, 2004
Background: The aim of the study was to examine the practicability and implementation efficacy of an alcohol outpatient detoxification model and the concomitant `motivational' psychotherapeutic approach.
Soyka, Michael, Michael Horak, Michael Soyka, Horak, M.   +3 more
core   +1 more source

Dexmedetomidine and iatrogenic withdrawal syndrome in critically ILL children

, 2021
Background: Iatrogenic withdrawal syndrome is a well-known adverse effect of sedatives and analgesics commonly used in patients receiving mechanical ventilation in the pediatric intensive care unit, with an incidence of up to 64.6%.
Ward, Catherine S., Geven, Barbara M., van Woensel, Job B. M., Maaskant, Jolanda M.   +3 more
core   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

Systematic Multi‐Level Analyses Decode the Arthritis‐Neurodegeneration Axis With In Vivo Validation

Advanced Science, EarlyView.
Arthritis and neurodegeneration are usually studied as separate disorders, but this study connects them through population evidence, genetic inference, transcriptomic mapping, and mouse models. It highlights RNF40 as a context‐dependent joint‐brain candidate, induced in inflammatory joints yet functionally linked to dopamine‐neuron vulnerability ...
Jinwen Wang, Wenhui Xie, Lei Yang, Zhengrong Wang, Yi Huang, Peng Huang, Yuan Liu, Jun Hu   +7 more
wiley   +1 more source

Preventive Effects of Forced Exercise against Alcohol-induced Physical Dependency and Reduction of Pain Perception Threshold

International Journal of Preventive Medicine, 2014
Background: Treatment of postabstinence syndrome of alcohol is one of the major strategies of alcoholism treatment. Exercise can be modulated major brain pathways such as a reward system and pain perception centers.
Majid Motaghinejad, Majid Asadi Ghaleni, Ozra Motaghinejad   +2 more
doaj  

Immediate and Gradual Withdrawal of Immunosuppression After Kidney Graft Loss Lead to Similar Outcomes

Transplant International
The management of immunosuppression in dialysis patients with a failed kidney transplant remains a pending question, and different approaches to immunosuppression weaning have been proposed.
Asmaa Nabil, Asmaa Nabil, Nicolas Congy-Jolivet, Nicolas Congy-Jolivet, Nicolas Congy-Jolivet, Amandine Darres, Pierre Guy, Olivier Marion, Jean Milhes, Thomas Prudhomme, Thomas Prudhomme, Nassim Kamar, Nassim Kamar, Nassim Kamar, Arnaud Del Bello, Arnaud Del Bello, Arnaud Del Bello   +16 more
doaj   +1 more source

Pengaruh Pemeberian Ekstrak Etanol Delphinium Grandifl orum Terhadap Tanda Somatik dan Tanda Afektif Nicotine Withdrawal Syndrome pada Tikus Sprague Dawley Betina yang Diberi Nikotin Peroral

IJNP (Indonesian Journal of Nursing Practices), 2014
Background. Nicotine abstinence will lead nicotine withdrawal syndrome in somatic signs and aff  ective signs. Somatic signs such as body weight change. Aff  ective signs such as sign of anxiety.
Nurvita Risdiana
doaj   +1 more source

A Rare De Novo Missense Mutation in IFT122 Confers a Genetic Susceptibility Factor of Idiopathic Pediatric Uveitis Via Trio‐based Whole‐Exome Sequencing

Advanced Science, EarlyView.
A rare de novo IFT122‐A773E variant is identified in idiopathic pediatric uveitis and shown to exacerbate retinal inflammation and barrier dysfunction. Mechanistically, the variant enhances IFT43 interaction, elevates calcium signaling, and activates the MEK/ERK/FRA1 axis, revealing a previously unrecognized cilia‐associated pathway that may increase ...
Qian Zhou, Jiaxing Huang, Yilin Wang, Xingran Li, Xianyang Liu, Lingyu Dai, Hongshun Li, Qingfeng Wang, Jiangyi Liu, Guannan Su, Wanyun Zhang, Yang Deng, Qingfeng Cao, Yujie Lai, Xiang Luo, Changwei Huang, Ling Chen, Shengping Hou, Peizeng Yang   +18 more
wiley   +1 more source

Repurposing a Small Molecule Plant Hormone as a Tunable ON‐Switch for CAR‐T Cell Immunotherapy

Advanced Science, EarlyView.
By engineering a receptor system integrating the plant auxin receptor AFB1 with its co‐receptor IAA7, we enable ligand‐dependent interactions triggered by the plant hormone auxins. This design allows rapid, reversible, and dose‐dependent T cell activation, resulting in potent cytotoxicity against B‐cell lymphoma in vitro and in vivo.
Hongxiang Zeng, Lei Zheng, Rongkun Tao, Sirui Zheng, Yanke Zhong, Yongxia Niu, Peng Zhang, Xiang Ma, Chen Yang, Min Zhang, Fuyu Duan, Jing Yang, Xuan Wei, Xiang Zhou, Zhenbiao Yang, Zhaoxi Sun, Qizhou Lian   +16 more
wiley   +1 more source

Pathological regional blood flow in opiate-dependent patients during withdrawal: A HMPAO-SPECT study [PDF]

, 1998
The aims of the present study were to investigate regional cerebral blood flow (rCBF) in heroin-dependent patients during withdrawal and to assess the relation between these changes and duration of heroin consumption and withdrawal data.
Krappel, C., Broich, K., Klemm, E., Biersack, H. J., Hoflich, G., Danos, P., Kasper, S., Grunwald, F., Möller, Hans-Jürgen, Overbeck, B.   +9 more
core   +1 more source