Differential Changes in Expression of Stress- and Metabolic-related Neuropeptides in the Rat Hypothalamus during Morphine Dependence and Withdrawal [PDF]
, 2013 Chronic morphine treatment and naloxone precipitated morphine withdrawal activates stress-related brain circuit and results in significant changes in food intake, body weight gain and energy metabolism.
Ferenczi, Szilamér +6 more
core +2 more sources
Alcohol Withdrawal – Therapeutical Management in Surgical Patients with Upper Intestinal Bleeding [PDF]
, 2015 Psychological dependence involves a desire to use a drug to avoid the unpleasant withdrawal syndrome that results from cessation of exposure to it. Alcohol withdrawal syndrome is one of the most feared complications of alcohol addiction and sometimes can
Bogdan, Popescu +5 more
core +6 more sources
Beneficial Effects of Rosmarinus Officinalis for Treatment of Opium Withdrawal Syndrome during Addiction Treatment Programs: A Clinical Trial [PDF]
Addiction and Health, 2013 Background: Withdrawal syndrome may influence patient's motivation for participation in addiction treatment programs. Management of the symptoms can improve the success rate of addiction treatment programs.
Hassan Solhi +6 more
doaj
Effects of Sodium Selenite and Vitamin E on the Development of Morphine Dependency in Mice [PDF]
Pharmaceutical Sciences, 2021 Background: Antioxidant drugs may be useful in preventing morphine-induced dependency bysuppressing oxidative stress. Vitamin E which has many essential roles in the body is a powerfulantioxidant. On the other hand, selenium is an essential trace element
Bohloul Habibi-Asl +5 more
doaj +1 more source
Baclofen: Therapeutic and Toxic Mechanisms of Action (Review)
Общая реаниматология, 2020 Baclofen is a muscle relaxant, which is a beta-p-chlorophenyl derivative of an inhibitory neurotransmitter GABA. This drug may have serious side effects and cause life-threatening conditions which may recellular receptors to clarify the pathogenesis of ...
О. L. Romanova +2 more
doaj +1 more source
DSM-5 criteria for substance use disorders: recommendations and rationale. [PDF]
, 2013 Since DSM-IV was published in 1994, its approach to substance use disorders has come under scrutiny. Strengths were identified (notably, reliability and validity of dependence), but concerns have also arisen.
Auriacombe, Marc +11 more
core +1 more source
Journal of Mazandaran University of Medical Sciences, 2022 Background and purpose: The harmful effects of morphine on the liver after withdrawal syndrome are unclear. In this experiment, we investigated the effects of exercise on oxidative stress, liver inflammation, liver enzymes, and liver histology after ...
Ebrahim Abbasi +6 more
doaj
Herbal therapy in opioid withdrawal syndrome: A systematic review of randomized clinical trials [PDF]
Addiction and Health, 2022 Background: Medicinal plants have revealed much attention as an alternative or complementary treatment for opioid withdrawal syndrome. The current review collects all available literature to verify the efficiency of herbal remedies in the management of ...
Mohammad Hadi Nematollahi +5 more
doaj +1 more source
Elevated PAI-1 is associated with poor clinical outcomes in pediatric patients with acute lung injury. [PDF]
, 2009 PurposeDeposition of fibrin in the alveolar space is a hallmark of acute lung injury (ALI). Plasminogen activator inhibitor-1 (PAI-1) is an antifibrinolytic agent that is activated during inflammation. Increased plasma and pulmonary edema fluid levels of
Brady, Sandra +4 more
core +2 more sources
Endocrine Withdrawal Syndromes [PDF]
Endocrine Reviews, 2003 Hypersecretion of endogenous hormones or chronic administration of high doses of the same hormones induces varying degrees of tolerance and dependence. Elimination of hormone hypersecretion or discontinuation of hormone therapy may result in a mixed picture of two syndromes: a typical hormone deficiency syndrome and a generic withdrawal syndrome. Thus,
Karel Pacak +3 more
openaire +3 more sources