Results 51 to 60 of about 171,182 (259)

Activation of ERBB4 Pathway Inhibits Pathological Transdifferentiation of Lung Epithelial Progenitors into CD66c+ Basal Cells in Severe Lung Injury

Advanced Science, EarlyView.
In fibrotic distal lung regions, CD66c+ basal cells emerge as a pathological state. Using human distal lung organoids, this study identifies CD66c+ basal cells as a pro‐fibrotic state arising through transdifferentiation from secretory, AT2, and basal cells.
Kaijun Lin, Xinran Deng, Haonan Wang, Yamei Jiang, Jian Sun, Hailin Ding, Ming Ye, Xiaoting Wang, Yu Wang, Li Yuan, Zhenju Song, Xinhua Lin, Shenfei Sun, Ning Jiang   +13 more
wiley   +1 more source

Pengaruh Pemeberian Ekstrak Etanol Delphinium Grandifl orum Terhadap Tanda Somatik dan Tanda Afektif Nicotine Withdrawal Syndrome pada Tikus Sprague Dawley Betina yang Diberi Nikotin Peroral

IJNP (Indonesian Journal of Nursing Practices), 2014
Background. Nicotine abstinence will lead nicotine withdrawal syndrome in somatic signs and aff  ective signs. Somatic signs such as body weight change. Aff  ective signs such as sign of anxiety.
Nurvita Risdiana
doaj   +1 more source

Proton FLASH Exposure Preserves Gut Commensal Microbiomes and Spares Intestinal Stem Cells

Advanced Science, EarlyView.
This study highlights the role of Proton FLASH abdominal irradiation in sparing of intestinal stem cells and preservation of key gut microbial population resulting minimization of radiation toxicity in intestinal epithelium in mice. Our findings support the potential of Proton FLASH to improve the therapeutic ratio for abdominal radiation exposure ...
Rishi Man Chugh, Payel Bhanja, Emily Schueddig, Jufri Setianegara, Yuting Lin, Kenny Guida, Shujah Rehman, Stacey Krepel, Devin Koestler, Ronald C. Chen, Katherine L. Cook, Subhrajit Saha   +11 more
wiley   +1 more source

Immediate and Gradual Withdrawal of Immunosuppression After Kidney Graft Loss Lead to Similar Outcomes

Transplant International
The management of immunosuppression in dialysis patients with a failed kidney transplant remains a pending question, and different approaches to immunosuppression weaning have been proposed.
Asmaa Nabil, Asmaa Nabil, Nicolas Congy-Jolivet, Nicolas Congy-Jolivet, Nicolas Congy-Jolivet, Amandine Darres, Pierre Guy, Olivier Marion, Jean Milhes, Thomas Prudhomme, Thomas Prudhomme, Nassim Kamar, Nassim Kamar, Nassim Kamar, Arnaud Del Bello, Arnaud Del Bello, Arnaud Del Bello   +16 more
doaj   +1 more source

Status dystonicus resembling the intrathecal baclofen withdrawal syndrome: a case report and review of the literature

Journal of Medical Case Reports, 2010
Introduction Status dystonicus is a rare but life-threatening disorder characterized by increasingly frequent and severe episodes of generalized dystonia that may occur in patients with primary or secondary dystonia.
Muirhead William, Jalloh Ibrahim, Vloeberghs Michael   +2 more
doaj   +1 more source

The alcohol withdrawal syndrome

Annals of Emergency Medicine, 1982
Summary The alcohol withdrawal syndrome represents an acute medical emergency of probable multifactorial cause. The emergency physician who sees only one point in the spectrum of the patient's disease must be aware of the other clinical entities simulating its presentation.
openaire   +3 more sources

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

The Effects of Aqueous Extracts of Purtulaca oleracea on Withdrawal Syndrome in Mice

Journal of Medicinal Plants, 2009
Background: Purtulaca pleracea (PO) overgrows in the different parts of Iran. In previous studies, the extract of P.O showed antinociceptive, anxiolytic and anti inflammation effects in Mice and rats.
H Miladi-Gorgi, AA Vafaei, AA Taherian, T Vaezi   +3 more
doaj  

The Effects of Quetiapine on Craving and Withdrawal Symptoms in Methamphetamine Abuse: A Randomized, Double-Blind, Placebo-Controlled Trial

International Journal of Medical Toxicology and Forensic Medicine, 2020
Background: Patients with Methamphetamine Abuse (MA) are susceptible to many complications like craving, and withdrawal symptoms. These trials were designed to evaluate the effect of quetiapine administration on craving and withdrawal symptoms in MA ...
Najme Sadat Javdan , Amir Ghaderi , Hamid Reza Banafshe   +2 more
doaj   +1 more source

Tailored Porous Bimetallic Nanozyme Platform for Full‐Cycle Therapeutics of Intestinal Ischemia/Reperfusion

Advanced Science, EarlyView.
ABSTRACT Intestinal ischemia/reperfusion (I/R) injury presents a biphasic pathology: an acute oxidative‐inflammatory phase leading to organ failure, and a recovery phase marked by mucosal dysfunction and bacterial translocation. The developed MPB@TA‐Cu‐Ma nanocomposite functions as a dual‐phase therapeutic platform with significant efficacy. It rapidly
Chenghao Qiu, Wenjing Xian, Mengxue Wang, Guozhi Zhao, Yanhuo Zhang, Zhiyu Zhou, Bo Sheng, Zhuo Zhen, Xie Liu, Shouwen Diao, Mengwei Tu, Chen Qiu, Huixian Wang, Jianbo Zhang, Peng Zhu, Tong Li   +15 more
wiley   +1 more source