Results 251 to 260 of about 427,328 (297)

Ligand-dependent Wnt signaling promotes gastric cancer metastasis through hyaluronan expression in microenvironment. [PDF]

Nat Commun
Furutani Y, Oshima H, Hong CP, Choi S, Machi R, Nakayama M, Murakami K, Yagi S, Ito Y, Maeda D, Inaki N, Barker N, Oshima M.   +12 more
europepmc   +1 more source

<i>DNASE1L3</i> Mediates Hepatocellular Carcinoma Tumor Growth and Organoid Models via the Wnt/<b>β</b>-Catenin Signaling Pathway. [PDF]

Oncol Res
Zhang S, Zhao Y, Geng L, Song F, Feng L, Jiang J, Cai Q, Fan F.   +7 more
europepmc   +1 more source

Prolonged Wnt3a exposure tolerizes macrophages to inflammatory stimuli. [PDF]

Front Immunol
Tigue ML, Jagarlamudi R, Chi C, Diaz D, Chen HC, Sheng Q, Chen SC, Schwarzkopf A, Goettel JA, Pua HH, Lee E, Weiss VL.   +11 more
europepmc   +1 more source

Postnatal treadmill exercise alleviates cognitive deficits in offspring exposed to gestational diabetes mellitus via reactivation of the hippocampal Wnt/β-catenin signaling pathway. [PDF]

J Exerc Rehabil
Baek KW, Won JH, Lee SJ.
europepmc   +1 more source

The role of microRNAs in modulating Wnt signaling pathway dynamics and their therapeutic implications in non-small cell lung cancer. [PDF]

Discov Oncol
Wang Y, Yarmukhamedova S, Alkhamessi RN, Kadham MJ, AAboqader Al-Aouadi RF, Thakur V, Naser RH, Lakshmaiya N, Jayapal P, Almagharbeh WT, Sârbu I, Aditya FA, Ciongradi CI, Hamzehzadeh S.   +13 more
europepmc   +1 more source

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WNT signalling and haematopoiesis: a WNT–WNT situation

Nature Reviews Immunology, 2005
The evolutionarily conserved WNT-signalling pathway has pivotal roles during the development of many organ systems, and dysregulated WNT signalling is a key factor in the initiation of various tumours. Recent studies have implicated a role for WNT signal transduction at several stages of lymphocyte development and in the self-renewal of haematopoietic ...
Frank J T Staal
exaly   +6 more sources

Wnt Versus Wnt

Science Signaling, 2003
In the canonical Wnt signaling pathway, Wnts cause stabilization of β-catenin and consequent changes in gene expression. But not all Wnts appear to signal in this way. Developmental actions of Wnt-5, for example, appear not to be mediated by β-catenin, and now two papers show that Wnt-5 actually antagonizes canonical Wnt signaling ...
openaire   +2 more sources

Preventing WNT signalling [PDF]

Nature Reviews Molecular Cell Biology, 2012
Simon Bekker-Jensen
exaly   +3 more sources

Rethinking WNT signaling

Trends in Genetics, 2004
Recent research on the WNT signaling pathway warrants a reassessment of the basic mechanism that transmits signal from the membrane-bound receptor to the nucleus. This article incorporates these findings into a revised model for pathway activation. We propose that the control of Axin stability, rather than the control of ZW3 phosphorylation of the ...
Nicholas S, Tolwinski, Eric, Wieschaus
openaire   +2 more sources

Targeting Oncogenic WNT Signalling with WNT Signalling-Derived Peptides

2021
WNT signalling is known to be a crucial regulator of embryonic development and tissue homeostasis. Aberrant expression of WNT signalling elements or their mutations has been implicated in carcinogenesis and/or the progression of several different cancer types.
Vikas, Yadav, Njainday, Jobe, Lubna, Mehdawi, Tommy, Andersson   +3 more
openaire   +2 more sources