Results 261 to 270 of about 176,136 (293)

ADAMTS9‐AS2 Disrupts Docetaxel‐Resistance in Castration‐Resistant Prostate Cancer via Stemness Suppression and Ferroptosis Induction

Advanced Science, EarlyView.
This study uncovered a dual‐track mechanism by which ADAMTS9‐AS2 overcame chemoresistance in CRPC: suppressing cancer stemness through the FOXF2/TGF‐β2 pathway, and triggering ferroptosis via competitive SLC7A11 sequestration. Polymeric materials co‐targeting these vulnerabilities further boost docetaxel sensitivity, highlighting a compelling strategy ...
Ji Liu, Yan Gao, Yadong Guo, Junfeng Zhang, Wentao Zhang, Zhuoran Gu, Haotian Chen, Chengqi Jin, Peng Luo, Shiyu Mao, Yajuan Hao, Shuo Shi, Xudong Yao   +12 more
wiley   +1 more source

Towards a phylogenetically informed approach to solving protein-protein interactions. [PDF]

Biochem Soc Trans
Lim CS, Mace P, Fineran PC, Gardner PP.
europepmc   +1 more source

Primary cilia function as hubs for signal transduction. [PDF]

Cell Biosci
Li B, He YY, Yang ZM.
europepmc   +1 more source

Wnt5a Regulates Focal Adhesion Formation to Promote Migration in Ewing Sarcoma. [PDF]

Cancers (Basel)
Baker A, Singhal A, Jacobson S, Loeb DM.
europepmc   +1 more source

Regulation of glypican 6-mediated Wnt activation maintains TDP-43 nuclear localization in neurons. [PDF]

Sci Rep
Zhang N, Sockanathan S.
europepmc   +1 more source

Research Progress of LEF1 Gene in Malignant Tumors. [PDF]

Clin Med Insights Oncol
Zhao Y, Pan C, Yang S, Ma X, Yao Y, Li Z, Ma Q, Wang X, Wang C, Nie Z.   +9 more
europepmc   +1 more source

MRPS16 Regulates NFATC2 Through the Wnt/β-Catenin Pathway to Promote Glioma Proliferation. [PDF]

J Cell Mol Med
Li X, Yu S, Wang M, Gong Z, Cheng Q, Wang X, Jiang X.   +6 more
europepmc   +1 more source