Results 301 to 310 of about 5,645,262 (348)
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Wnt signaling in periodontitis
Clinical Oral Investigations, 2023This study aimed to evaluate the Wnt/β-catenin signaling pathway activity in gingival samples obtained from patients with periodontitis.Fifteen patients with stage III grade B (SIIIGB) and eleven with stage III grade C (SIIIGC) periodontitis were included and compared to 15 control subjects.
ÖNDER, CANAN +7 more
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Wnt signaling pathway: A comprehensive review
Cell Biology International, 2022Wnt signaling is an evolutionary cell‐to‐cell coordination mechanism and it is highly critical for a variety of physiological processes of an organism's body, including stem cell regeneration, proliferation, division, migration, polarity of a cell ...
Rabia Hayat, M. Manzoor, A. Hussain
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Recent Development of Wnt Signaling Pathway Inhibitors for Cancer Therapeutics
Current Oncology Reports, 2019Jijun Hao, Hao Jijun
exaly +2 more sources
Wnt signaling pathway in cancer immunotherapy.
Cancer Letters, 2021Wnt/β-catenin signaling is a highly conserved pathway that regulates cell proliferation, differentiation, apoptosis, stem cell self-renewal, tissue homeostasis, and wound healing.
Yang Zhou +5 more
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WNT signalling and haematopoiesis: a WNT–WNT situation
Nature Reviews Immunology, 2005The evolutionarily conserved WNT-signalling pathway has pivotal roles during the development of many organ systems, and dysregulated WNT signalling is a key factor in the initiation of various tumours. Recent studies have implicated a role for WNT signal transduction at several stages of lymphocyte development and in the self-renewal of haematopoietic ...
Staal, Frank, Clevers, HC
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Cell Biology of Canonical Wnt Signaling.
Annual Review of Cell and Developmental Biology, 2021Wnt signaling has multiple functions beyond the transcriptional effects of β-catenin stabilization. We review recent investigations that uncover new cell physiological effects through the regulation of Wnt receptor endocytosis, Wnt-induced stabilization ...
L. Albrecht +2 more
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Wnt signaling pathways in biology and disease: mechanisms and therapeutic advances
Signal Transduction and Targeted TherapyThe Wnt signaling pathway is critically involved in orchestrating cellular functions such as proliferation, migration, survival, and cell fate determination during development.
Chen Xue +5 more
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Wnt signaling and osteoblastogenesis
Reviews in Endocrine and Metabolic Disorders, 2006Wnts are a large family of growth factors that mediate fundamental biological processes like embryogenesis, organogenesis and tumorigenesis. These proteins bind to a membrane receptor complex comprised of a frizzled (FZD) G-protein-coupled receptor (GPCRs) and a low-density lipoprotein (LDL) receptor-related protein (LRP).
Peter V N, Bodine, Barry S, Komm
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Current Opinion in Immunology, 2003
Wnt proteins are secreted signaling molecules that regulate cell-to-cell interactions during embryogenesis in many different tissues and species. Wnt signaling is required for normal thymocyte development, most dramatically at the pro-T-cell stage, although recent reports also indicate a role for Wnt proteins in later stages of thymocyte ...
Staal, Frank, Clevers, HC
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Wnt proteins are secreted signaling molecules that regulate cell-to-cell interactions during embryogenesis in many different tissues and species. Wnt signaling is required for normal thymocyte development, most dramatically at the pro-T-cell stage, although recent reports also indicate a role for Wnt proteins in later stages of thymocyte ...
Staal, Frank, Clevers, HC
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Wnt signaling in the vasculature
Angiogenesis, 2002The Wnt signaling pathway regulates normal development as well as a variety of pathologies. Studies of the Wnt pathway have focused largely on very early development and on tumorigenesis. Recent observations point to a role for Wnt signaling in vessel development and pathology. Although not yet investigated systematically, several Wnt ligands have been
A M, Goodwin, P A, D'Amore
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