Results 111 to 120 of about 1,026,340 (233)

Inhibition of the Wnt Signaling Pathway by the PR61 Subunit of Protein Phosphatase 2A [PDF]

, 2001
Hideki Yamamoto, Toshihide Hinoi, Tatsuo Michiue, Akimasa Fukui, Hirofumi Usui, Veerle Janssens, Christine Van Hoof, Jozef Goris, Makoto Asashima, Akira Kikuchi   +9 more
openalex   +1 more source

Autophagy and the Wnt Signaling Pathway: A Focus on Wnt/β-catenin signaling.

Biochimica et biophysica acta. Molecular cell research, 2020
Shahrokh Lorzadeh, L. Kohan, S. Ghavami, N. Azarpira   +3 more
semanticscholar   +1 more source

Wnt/β-catenin signaling components and mechanisms in bone formation, homeostasis, and disease

Bone Research
Wnts are secreted, lipid-modified proteins that bind to different receptors on the cell surface to activate canonical or non-canonical Wnt signaling pathways, which control various biological processes throughout embryonic development and adult life ...
Lifang Hu, Wei Chen, Airong Qian, Yi-Ping Li   +3 more
semanticscholar   +1 more source

Identification of a Wnt/β-Catenin Signaling Pathway in Human Thyroid Cells [PDF]

, 2001
Karen Helmbrecht, Andreas Kispert, Reinhard von Wasielewski, Georg Brabant   +3 more
openalex   +1 more source

Canonical and noncanonical Wnt signaling: Multilayered mediators, signaling mechanisms and major signaling crosstalk

Genes and Diseases
Wnt signaling plays a major role in regulating cell proliferation and differentiation. The Wnt ligands are a family of 19 secreted glycoproteins that mediate their signaling effects via binding to Frizzled receptors and LRP5/6 coreceptors and transducing
Kevin Qin, Michael Yu, Jiaming Fan, Hongwei Wang, Piao Zhao, Guozhi Zhao, Wei Zeng, Connie Chen, Yonghui Wang, Annie Wang, Zander Schwartz, Jeffrey Hong, Lily Song, William Wagstaff, Rex C. Haydon, Hue H. Luu, Sherwin H. Ho, Jason Strelzow, Russell R. Reid, Tong-Chuan He, Lewis L. Shi   +20 more
doaj  

Inhibitory effect of a presenilin 1 mutation on the Wnt signalling pathway by enhancement of β‐catenin phosphorylation [PDF]

, 2001
Yuuki Kawamura, Akira Kikuchi, Ritsuko Takada, Shinji Takada, Shinji Sudoh, Sayumi Shibamoto, Katsuhiko Yanagisawa, Hiroto Komano   +7 more
openalex   +1 more source

Blocking the WNT/β-catenin pathway in cancer treatment:pharmacological targets and drug therapeutic potential

Heliyon
The WNT/β-catenin signaling pathway plays crucial roles in tumorigenesis and relapse, metastasis, drug resistance, and tumor stemness maintenance. In most tumors, the WNT/β-catenin signaling pathway is often aberrantly activated.
Xi Zhao, Yunong Ma, Jiayang Luo, Kexin Xu, Peilin Tian, Cuixia Lu, Jiaxing Song   +6 more
doaj  

Wnt Pathway-Targeted Therapy in Gastrointestinal Cancers: Integrating Benchside Insights with Bedside Applications

Cells
The Wnt signaling pathway is critical in the onset and progression of gastrointestinal (GI) cancers. Anomalies in this pathway, often stemming from mutations in critical components such as adenomatous polyposis coli (APC) or β-catenin, lead to ...
Anirudh Nayak, Hannah Streiff, Ivan Gonzalez, Oluwabomi Oluwatomi Adekoya, Itzcoatl Silva, Anitha Kota Shenoy   +5 more
doaj   +1 more source

The expression of gene for beta catenin and p53 in meningioma [PDF]

, 2015
Meningeomi su primarni tumori središnjeg živčanog sustava. Beta-katenin je citoplazmatski protein kodiran genom CTNNB1. Sudjeluje u nastanku i održavanju međustaničnih veza i signalnom putu Wnt.
Logara, Monika
core   +1 more source

Low-Density Lipoprotein Receptor-Related Protein-5 Binds to Axin and Regulates the Canonical Wnt Signaling Pathway [PDF]

, 2001
Junhao Mao, Jiyong Wang, Bo Liu, Weijun Pan, Gist H. Farr, Christopher Flynn, Huidong Yuan, Shinji Takada, David Kimelman, Li Lin, Dianqing Wu   +10 more
openalex   +1 more source