Results 81 to 90 of about 1,026,340 (233)
Objective To evaluate the effects of Wnt signaling pathways on the CXCR4 expression of bone marrow mesenchymal stem cells(BMSCs),and to investigate the possible regulation mechanisms of the Wnt signaling pathways on the migration ability of BMSCs.Methods
SUN Ji-ping+4 more
doaj
The Wnt/β-catenin signaling pathway is crucial for embryonic development and adult tissue homeostasis. Dysregulation of Wnt signaling is linked to various developmental anomalies and diseases, notably cancer.
Shin Ae Oh+5 more
doaj +1 more source
Zebrafish Prickle, a Modulator of Noncanonical Wnt/Fz Signaling, Regulates Gastrulation Movements [PDF]
In addition to the canonical Wnt/β-catenin signaling pathway, at least two noncanonical Wnt/Fz pathways have been described: the planar cell polarity (PCP) pathway in Drosophila[1] and the Wnt/calcium pathway in vertebrate embryos [2].
Kaykas, Ajamete+4 more
core +1 more source
Wnt Signaling Pathway Related Genes In Hepatocellular Carcinoma [PDF]
Hepatocellular carcinoma (HCC) is an extremely difficult disease to manage and one of the ten most common cancers in Malaysia. However, the molecular mechanisms that contribute to tumour progression in hepatocarcinogenesis remain unknown.
Ban, Kechen
core
Anti-inflammatory activity of Wnt signaling in enteric nervous system: in vitro preliminary evidences in rat primary cultures [PDF]
Background: In the last years, Wnt signaling was demonstrated to regulate inflammatory processes. In particular, an increased expression of Wnts and Frizzled receptors was reported in inflammatory bowel disease (IBD) and ulcerative colitis to exert both ...
Anne, Schuster+7 more
core +2 more sources
Action and function of Wnt/β-catenin signaling in the progression from chronic hepatitis C to hepatocellular carcinoma [PDF]
Hepatitis C virus (HCV) infection is one of the leading causes of hepatocellular carcinoma (HCC) worldwide but the mechanistic basis as to how chronic HCV infection furthers the HCC process remains only poorly understood.
Fuhler, G.M. (Gwenny)+4 more
core +1 more source
How the Wnt signaling pathway protects from neurodegeneration: the mitochondrial scenario
Alzheimer’s disease (AD) is the most common neurodegenerative disorder and is characterized by progressive memory loss and cognitive decline. One of the hallmarks of AD is the overproduction of amyloid-beta aggregates that range from the toxic soluble ...
Macarena S. Arrázola+2 more
semanticscholar +1 more source
Wnt/beta-catenin/Tcf signaling: A critical pathway in gastrointestinal tumorigenesis [PDF]
Cancers of the gastrointestinal tract, including the liver, bile ducts, and pancreas, constitute the largest group of malignant tumors. Colorectal cancer is one of the most common neoplastic diseases in Western countries and one of the leading causes of ...
Bommer, G., Göke, B., Kolligs, F. T.
core +2 more sources
Wnt and the Wnt signaling pathway in bone development and disease.
Wnt signaling affects both bone modeling, which occurs during development, and bone remodeling, which is a lifelong process involving tissue renewal. Wnt signals are especially known to affect the differentiation of osteoblasts.
Yiping Wang+6 more
semanticscholar +1 more source
The Wnt signaling pathway is one of the most important and critical signaling pathways for maintaining cellular functions, such as cell proliferation and differentiation.
Jiayi Song+7 more
doaj +1 more source