Results 81 to 90 of about 1,026,340 (233)

The effects of canonical Wnt signaling pathways on the CXCR4 expression of bone marrow derived mesenchymal stem cells

open access: yesLinchuang shenzangbing zazhi, 2017
Objective To evaluate the effects of Wnt signaling pathways on the CXCR4 expression of bone marrow mesenchymal stem cells(BMSCs),and to investigate the possible regulation mechanisms of the Wnt signaling pathways on the migration ability of BMSCs.Methods
SUN Ji-ping   +4 more
doaj  

TMEM132A regulates Wnt/β-catenin signaling through stabilizing LRP6 during mouse embryonic development

open access: yesCell Communication and Signaling
The Wnt/β-catenin signaling pathway is crucial for embryonic development and adult tissue homeostasis. Dysregulation of Wnt signaling is linked to various developmental anomalies and diseases, notably cancer.
Shin Ae Oh   +5 more
doaj   +1 more source

Zebrafish Prickle, a Modulator of Noncanonical Wnt/Fz Signaling, Regulates Gastrulation Movements [PDF]

open access: yes, 2003
In addition to the canonical Wnt/β-catenin signaling pathway, at least two noncanonical Wnt/Fz pathways have been described: the planar cell polarity (PCP) pathway in Drosophila[1] and the Wnt/calcium pathway in vertebrate embryos [2].
Kaykas, Ajamete   +4 more
core   +1 more source

Wnt Signaling Pathway Related Genes In Hepatocellular Carcinoma [PDF]

open access: yes, 2002
Hepatocellular carcinoma (HCC) is an extremely difficult disease to manage and one of the ten most common cancers in Malaysia. However, the molecular mechanisms that contribute to tumour progression in hepatocarcinogenesis remain unknown.
Ban, Kechen
core  

Anti-inflammatory activity of Wnt signaling in enteric nervous system: in vitro preliminary evidences in rat primary cultures [PDF]

open access: yes, 2015
Background: In the last years, Wnt signaling was demonstrated to regulate inflammatory processes. In particular, an increased expression of Wnts and Frizzled receptors was reported in inflammatory bowel disease (IBD) and ulcerative colitis to exert both ...
Anne, Schuster   +7 more
core   +2 more sources

Action and function of Wnt/β-catenin signaling in the progression from chronic hepatitis C to hepatocellular carcinoma [PDF]

open access: yes, 2017
Hepatitis C virus (HCV) infection is one of the leading causes of hepatocellular carcinoma (HCC) worldwide but the mechanistic basis as to how chronic HCV infection furthers the HCC process remains only poorly understood.
Fuhler, G.M. (Gwenny)   +4 more
core   +1 more source

How the Wnt signaling pathway protects from neurodegeneration: the mitochondrial scenario

open access: yesFrontiers in Cellular Neuroscience, 2015
Alzheimer’s disease (AD) is the most common neurodegenerative disorder and is characterized by progressive memory loss and cognitive decline. One of the hallmarks of AD is the overproduction of amyloid-beta aggregates that range from the toxic soluble ...
Macarena S. Arrázola   +2 more
semanticscholar   +1 more source

Wnt/beta-catenin/Tcf signaling: A critical pathway in gastrointestinal tumorigenesis [PDF]

open access: yes, 2002
Cancers of the gastrointestinal tract, including the liver, bile ducts, and pancreas, constitute the largest group of malignant tumors. Colorectal cancer is one of the most common neoplastic diseases in Western countries and one of the leading causes of ...
Bommer, G., Göke, B., Kolligs, F. T.
core   +2 more sources

Wnt and the Wnt signaling pathway in bone development and disease.

open access: yesFrontiers in Bioscience, 2014
Wnt signaling affects both bone modeling, which occurs during development, and bone remodeling, which is a lifelong process involving tissue renewal. Wnt signals are especially known to affect the differentiation of osteoblasts.
Yiping Wang   +6 more
semanticscholar   +1 more source

Inhibitors of the Wnt pathway in osteoporosis: Mechanisms of action and potential as therapeutic targets

open access: yesBiomolecules & Biomedicine
The Wnt signaling pathway is one of the most important and critical signaling pathways for maintaining cellular functions, such as cell proliferation and differentiation.
Jiayi Song   +7 more
doaj   +1 more source

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