Methanogenesis and the Wood–Ljungdahl Pathway: An Ancient, Versatile, and Fragile Association [PDF]
Genome Biology and Evolution, 2016 Methanogenesis coupled to the Wood-Ljungdahl pathway is one of the most ancient metabolisms for energy generation and carbon fixation in the Archaea. Recent results are sensibly changing our view on the diversity of methane-cycling capabilities in this Domain of Life.
Guillaume Borrel +2 more
exaly +5 more sources
Potential for homoacetogenesis via the Wood–Ljungdahl pathway in Korarchaeia lineages from marine hydrothermal vents [PDF]
Environmental Microbiology Reports, 2023 Abstract The Wood–Ljungdahl pathway (WLP) is a key metabolic component of acetogenic bacteria where it acts as an electron sink. In Archaea, despite traditionally being linked to methanogenesis, the pathway has been found in several Thermoproteota and Asgardarchaeota lineages.
Francesca Vulcano +2 more
exaly +6 more sources
Enzymology of the Wood–Ljungdahl Pathway of Acetogenesis [PDF]
Annals of the New York Academy of Sciences, 2008 The biochemistry of acetogenesis is reviewed. The microbes that catalyze the reactions that are central to acetogenesis are described and the focus is on the enzymology of the process. These microbes play a key role in the global carbon cycle, producing over 10 trillion kilograms of acetic acid annually.
Stephen W Ragsdale
exaly +6 more sources
Acetogenesis and the Wood–Ljungdahl pathway of CO2 fixation [PDF]
Biochimica Et Biophysica Acta - Proteins and Proteomics, 2008 Conceptually, the simplest way to synthesize an organic molecule is to construct it one carbon at a time. The Wood-Ljungdahl pathway of CO(2) fixation involves this type of stepwise process. The biochemical events that underlie the condensation of two one-carbon units to form the two-carbon compound, acetate, have intrigued chemists, biochemists, and ...
Stephen W Ragsdale, Elizabeth Pierce
exaly +5 more sources
Diverse Energy-Conserving Pathways in Clostridium difficile: Growth in the Absence of Amino Acid Stickland Acceptors and the Role of the Wood-Ljungdahl Pathway [PDF]
Journal of Bacteriology, 2020 Clostridium difficile is an anaerobic, multidrug-resistant, toxin-producing pathogen with major health impacts worldwide. It is the only widespread pathogen harboring a complete set of Wood-Ljungdahl pathway (WLP) genes; however, the role of the WLP in C. difficile is poorly understood.
Simonida Gencic, David A Grahame
exaly +5 more sources
Bacterial estrogenesis without oxygen: Wood–Ljungdahl pathway likely contributed to the emergence of estrogens in the biosphere [PDF]
Proceedings of the National Academy of Sciences of the United States of AmericaAndrogen and estrogen, key sex hormones, were long thought to be exclusively produced by vertebrates. The O 2 -dependent aromatase that converts androgen to estrogen (estrogenesis) has never been identified in any prokaryotes. Here, we report the finding of anaerobic estrogenesis in a Peptococcaceae bacterium (
Po-Hsiang Wang +2 more
exaly +5 more sources
Incomplete Wood–Ljungdahl pathway facilitates one-carbon metabolism in organohalide-respiring Dehalococcoides mccartyi [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2014 Significance We have studied the functionality of an incomplete acetyl-CoA “Wood–Ljungdahl” pathway in a strictly organohalide-respiring bacterium, Dehalococcoides mccartyi . We found that in addition to its ability to incorporate exogenous formate, this pathway cleaves acetyl-CoA to generate methyl ...
Wei-Qin Zhuang, Shan Yi, Markus Bill
exaly +8 more sources
Insight into the function and evolution of the Wood-Ljungdahl pathway in Actinobacteria. [PDF]
ISME J, 2021 Abstract Carbon fixation by chemoautotrophic microbes such as homoacetogens had a major impact on the transition from the inorganic to the organic world. Recent reports have shown the presence of genes for key enzymes associated with the Wood–Ljungdahl pathway (WLP) in the phylum Actinobacteria, which adds to the diversity of potential ...
Jiao JY +17 more
europepmc +5 more sources
Sugar-inducible promoters for manipulation of core metabolic pathways in the thermophilic acetogen Thermoanaerobacter kivui [PDF]
Applied and Environmental MicrobiologyAcetogenic bacteria form an essential part of the global carbon cycle and show promise for green chemicals production thanks to their energy-efficient carbon fixation via the Wood-Ljungdahl pathway. Energy conservation in acetogens is dependent on one of
Benjamin Zeldes +6 more
doaj +2 more sources
Emerging Technologies for Biobutanol Production via Syngas Fermentation
GCB BioenergyBiobutanol offers significant advantages over ethanol as an advanced biofuel, but its large‐scale production via syngas fermentation faces critical challenges including low product titers, carbon inefficiency, and microbial toxicity.
Xuemei Wang +3 more
doaj +2 more sources