Bacterial estrogenesis without oxygen: Wood–Ljungdahl pathway likely contributed to the emergence of estrogens in the biosphere [PDF]
Proceedings of the National Academy of Sciences of the United States of AmericaAndrogen and estrogen, key sex hormones, were long thought to be exclusively produced by vertebrates. The O 2 -dependent aromatase that converts androgen to estrogen (estrogenesis) has never been identified in any prokaryotes.
Yin-Ru Chiang +2 more
exaly +5 more sources
Incomplete Wood–Ljungdahl pathway facilitates one-carbon metabolism in organohalide-respiring Dehalococcoides mccartyi [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2014 Significance We have studied the functionality of an incomplete acetyl-CoA “Wood–Ljungdahl” pathway in a strictly organohalide-respiring bacterium, Dehalococcoides mccartyi .
Markus Bill +2 more
exaly +8 more sources
Potential for homoacetogenesis via the Wood-Ljungdahl pathway in Korarchaeia lineages from marine hydrothermal vents. [PDF]
Environ Microbiol Rep, 2023 Abstract The Wood–Ljungdahl pathway (WLP) is a key metabolic component of acetogenic bacteria where it acts as an electron sink. In Archaea, despite traditionally being linked to methanogenesis, the pathway has been found in several Thermoproteota and Asgardarchaeota lineages.
Vulcano F +4 more
europepmc +5 more sources
Genomic Insights into Syntrophic Lifestyle of 'Candidatus Contubernalis alkaliaceticus' Based on the Reversed Wood-Ljungdahl Pathway and Mechanism of Direct Electron Transfer. [PDF]
Life (Basel), 2023 The anaerobic oxidation of fatty acids and alcohols occurs near the thermodynamic limit of life. This process is driven by syntrophic bacteria that oxidize fatty acids and/or alcohols, their syntrophic partners that consume the products of this oxidation, and the pathways for interspecies electron exchange via these products or direct interspecies ...
Frolov EN +3 more
europepmc +4 more sources
Wood-Ljungdahl pathway utilisation during in situ H2 biomethanation [PDF]
Science of the Total Environment, 2022 Biogas production from organic waste is a waste-to-energy technology with the potential to contribute significantly to sustainable energy production. Upgrading of biogas using in situ biomethanation with hydrogen has the potential for surplus electricity storage, and delivery of biogas with a methane content of >90%, allowing for easier integration ...
Michael Vedel Wegener Kofoed +2 more
exaly +4 more sources
Reduction, evolutionary pattern and positive selection of genes encoding formate dehydrogenase in Wood-Ljungdahl pathway of gastrointestinal acetogens suggests their adaptation to formate-rich habitats. [PDF]
Environ Microbiol Rep, 2023 Abstract Acetogens are anaerobes using Wood–Ljungdahl pathway (WLP) as the terminal electron acceptor for both assimilation and dissimilation of CO 2 and widely distributed in diverse habitats. However, their habitat adaptation is often unclear.
Yao Y +5 more
europepmc +3 more sources
Wood-Ljungdahl pathway encoding anaerobes facilitate low-cost primary production in hypersaline sediments at Great Salt Lake, Utah. [PDF]
FEMS Microbiol EcolAbstract Little is known of primary production in dark hypersaline ecosystems despite the prevalence of such environments on Earth today and throughout its geologic history. Here, we generated and analyzed metagenome-assembled genomes (MAGs) organized as operational taxonomic units (OTUs) from three depth intervals along a 30-cm sediment
Shoemaker A +10 more
europepmc +3 more sources
Functional Expression of the Clostridium ljungdahlii Acetyl-Coenzyme A Synthase in Clostridium acetobutylicum as Demonstrated by a Novel In Vivo CO Exchange Activity En Route to Heterologous Installation of a Functional Wood-Ljungdahl Pathway. [PDF]
Appl Environ Microbiol, 2018 ABSTRACTEngineering the Wood-Ljungdahl pathway (WLP) in the established industrial organismClostridium acetobutylicumwould allow for the conversion of carbohydrates into butanol, acetone, and other metabolites at higher yields than are currently possible, while minimizing CO2and H2release.
Fast AG, Papoutsakis ET.
europepmc +4 more sources
Sugar-inducible promoters for manipulation of core metabolic pathways in the thermophilic acetogen Thermoanaerobacter kivui [PDF]
Applied and Environmental MicrobiologyAcetogenic bacteria form an essential part of the global carbon cycle and show promise for green chemicals production thanks to their energy-efficient carbon fixation via the Wood-Ljungdahl pathway. Energy conservation in acetogens is dependent on one of
Benjamin Zeldes +6 more
doaj +2 more sources
Metagenomic analysis revealed the presence of novel Actinomycetota “Candidatus Solincola uaceae” sp. nov., obtained from a hot spring [PDF]
Scientific ReportsMetagenomic analysis of the hot spring led to the recovery of a high-quality metagenome-assembled genome (MAG), MPNR_HS_01, affiliated with the phylum Actinomycetota.
Warunya Suksa +9 more
doaj +2 more sources