Results 11 to 20 of about 3,076 (138)

Acetogenesis and the Wood–Ljungdahl Pathway of CO2 Fixation [PDF]

Biochimica Et Biophysica Acta - Proteins and Proteomics, 2008
Conceptually, the simplest way to synthesize an organic molecule is to construct it one carbon at a time. The Wood-Ljungdahl pathway of CO(2) fixation involves this type of stepwise process. The biochemical events that underlie the condensation of two one-carbon units to form the two-carbon compound, acetate, have intrigued chemists, biochemists, and ...
Stephen W Ragsdale, Elizabeth Pierce
exaly   +5 more sources

Enzymology of the Wood–Ljungdahl Pathway of Acetogenesis [PDF]

Annals of the New York Academy of Sciences, 2008
The biochemistry of acetogenesis is reviewed. The microbes that catalyze the reactions that are central to acetogenesis are described and the focus is on the enzymology of the process. These microbes play a key role in the global carbon cycle, producing over 10 trillion kilograms of acetic acid annually.
Stephen W Ragsdale
exaly   +6 more sources

Insight into the function and evolution of the Wood-Ljungdahl pathway in Actinobacteria. [PDF]

ISME J, 2021
Abstract Carbon fixation by chemoautotrophic microbes such as homoacetogens had a major impact on the transition from the inorganic to the organic world. Recent reports have shown the presence of genes for key enzymes associated with the Wood–Ljungdahl pathway (WLP) in the phylum Actinobacteria, which adds to the diversity of potential ...
Jiao JY, Fu L, Hua ZS, Liu L, Salam N, Liu PF, Lv AP, Wu G, Xian WD, Zhu Q, Zhou EM, Fang BZ, Oren A, Hedlund BP, Jiang HC, Knight R, Cheng L, Li WJ.   +17 more
europepmc   +5 more sources

Genomic Insights into Syntrophic Lifestyle of 'Candidatus Contubernalis alkaliaceticus' Based on the Reversed Wood-Ljungdahl Pathway and Mechanism of Direct Electron Transfer. [PDF]

Life (Basel), 2023
The anaerobic oxidation of fatty acids and alcohols occurs near the thermodynamic limit of life. This process is driven by syntrophic bacteria that oxidize fatty acids and/or alcohols, their syntrophic partners that consume the products of this oxidation, and the pathways for interspecies electron exchange via these products or direct interspecies ...
Frolov EN, Gavrilov SN, Toshchakov SV, Zavarzina DG.   +3 more
europepmc   +4 more sources

Reduction, evolutionary pattern and positive selection of genes encoding formate dehydrogenase in Wood-Ljungdahl pathway of gastrointestinal acetogens suggests their adaptation to formate-rich habitats. [PDF]

Environ Microbiol Rep, 2023
Abstract Acetogens are anaerobes using Wood–Ljungdahl pathway (WLP) as the terminal electron acceptor for both assimilation and dissimilation of CO 2 and widely distributed in diverse habitats. However, their habitat adaptation is often unclear.
Yao Y, Fu B, Han D, Zhang Y, Wei Z, Liu H.   +5 more
europepmc   +3 more sources

Genome-Scale Analysis of Acetobacterium woodii Identifies Translational Regulation of Acetogenesis

mSystems, 2021
Acetogens synthesize acetyl-CoA via the CO2-fixing Wood-Ljungdahl pathway. Despite their ecological and biotechnological importance, their translational regulation of carbon and energy metabolisms remains unclear.
Jongoh Shin, Yoseb Song, Seulgi Kang, Sangrak Jin, Jung-Kul Lee, Dong Rip Kim, Suhyung Cho, Volker Müller, Byung-Kwan Cho   +8 more
doaj   +1 more source

Four families of folate-independent methionine synthases.

PLoS Genetics, 2021
Although most organisms synthesize methionine from homocysteine and methyl folates, some have "core" methionine synthases that lack folate-binding domains and use other methyl donors.
Morgan N Price, Adam M Deutschbauer, Adam P Arkin   +2 more
doaj   +1 more source

Cell-free prototyping enables implementation of optimized reverse β-oxidation pathways in heterotrophic and autotrophic bacteria

Nature Communications, 2022
An attractive route for carbon-negative synthesis of biochemical products is the reverse β-oxidation pathway coupled to the Wood-Ljungdahl pathway.
Bastian Vögeli, Luca Schulz, Shivani Garg, Katia Tarasava, James M. Clomburg, Seung Hwan Lee, Aislinn Gonnot, Elamar Hakim Moully, Blaise R. Kimmel, Loan Tran, Hunter Zeleznik, Steven D. Brown, Sean D. Simpson, Milan Mrksich, Ashty S. Karim, Ramon Gonzalez, Michael Köpke, Michael C. Jewett   +17 more
doaj   +1 more source

Syntrophic Acetate-Oxidizing Microbial Consortia Enriched from Full-Scale Mesophilic Food Waste Anaerobic Digesters Showing High Biodiversity and Functional Redundancy

mSystems, 2022
Syntrophic acetate oxidation (SAO) coupled with hydrogenotrophic methanogenesis (HM) plays a vital role in the anaerobic digestion of protein-rich feedstocks such as food wastes. However, current knowledge of the biodiversity and genetic potential of the
Chao Li, Liping Hao, Fan Lü, Haowen Duan, Hua Zhang, Pinjing He   +5 more
doaj   +1 more source

Wood-Ljungdahl pathway encoding anaerobes facilitate low-cost primary production in hypersaline sediments at Great Salt Lake, Utah. [PDF]

FEMS Microbiol Ecol
Abstract Little is known of primary production in dark hypersaline ecosystems despite the prevalence of such environments on Earth today and throughout its geologic history. Here, we generated and analyzed metagenome-assembled genomes (MAGs) organized as operational taxonomic units (OTUs) from three depth intervals along a 30-cm sediment
Shoemaker A, Maritan A, Cosar S, Nupp S, Menchaca A, Jackson T, Dang A, Baxter BK, Colman DR, Dunham EC, Boyd ES.   +10 more
europepmc   +3 more sources