Results 21 to 30 of about 2,862 (133)

Metagenomic analysis revealed the presence of novel Actinomycetota “Candidatus Solincola uaceae” sp. nov., obtained from a hot spring [PDF]

Scientific Reports
Metagenomic analysis of the hot spring led to the recovery of a high-quality metagenome-assembled genome (MAG), MPNR_HS_01, affiliated with the phylum Actinomycetota.
Warunya Suksa, Wen-Jun Li, Zhen-Hao Luo, Jian-Yu Jiao, Vania Ponce, Kattia Nuñez-Montero, Patricio Arce-Johnson, Neeta Raj Sharma, Arinthip Thamchaipenet, Manik Prabhu Narsing Rao   +9 more
doaj   +2 more sources

Genomic Insights into Syntrophic Lifestyle of 'Candidatus Contubernalis alkaliaceticus' Based on the Reversed Wood-Ljungdahl Pathway and Mechanism of Direct Electron Transfer. [PDF]

Life (Basel), 2023
The anaerobic oxidation of fatty acids and alcohols occurs near the thermodynamic limit of life. This process is driven by syntrophic bacteria that oxidize fatty acids and/or alcohols, their syntrophic partners that consume the products of this oxidation, and the pathways for interspecies electron exchange via these products or direct interspecies ...
Frolov EN, Gavrilov SN, Toshchakov SV, Zavarzina DG.   +3 more
europepmc   +4 more sources

Reduction, evolutionary pattern and positive selection of genes encoding formate dehydrogenase in Wood-Ljungdahl pathway of gastrointestinal acetogens suggests their adaptation to formate-rich habitats. [PDF]

Environ Microbiol Rep, 2023
Abstract Acetogens are anaerobes using Wood–Ljungdahl pathway (WLP) as the terminal electron acceptor for both assimilation and dissimilation of CO 2 and widely distributed in diverse habitats. However, their habitat adaptation is often unclear.
Yao Y, Fu B, Han D, Zhang Y, Wei Z, Liu H.   +5 more
europepmc   +3 more sources

Genome-Scale Analysis of Acetobacterium woodii Identifies Translational Regulation of Acetogenesis

mSystems, 2021
Acetogens synthesize acetyl-CoA via the CO2-fixing Wood-Ljungdahl pathway. Despite their ecological and biotechnological importance, their translational regulation of carbon and energy metabolisms remains unclear.
Jongoh Shin, Yoseb Song, Seulgi Kang, Sangrak Jin, Jung-Kul Lee, Dong Rip Kim, Suhyung Cho, Volker Müller, Byung-Kwan Cho   +8 more
doaj   +1 more source

Four families of folate-independent methionine synthases.

PLoS Genetics, 2021
Although most organisms synthesize methionine from homocysteine and methyl folates, some have "core" methionine synthases that lack folate-binding domains and use other methyl donors.
Morgan N Price, Adam M Deutschbauer, Adam P Arkin   +2 more
doaj   +1 more source

Cell-free prototyping enables implementation of optimized reverse β-oxidation pathways in heterotrophic and autotrophic bacteria

Nature Communications, 2022
An attractive route for carbon-negative synthesis of biochemical products is the reverse β-oxidation pathway coupled to the Wood-Ljungdahl pathway.
Bastian Vögeli, Luca Schulz, Shivani Garg, Katia Tarasava, James M. Clomburg, Seung Hwan Lee, Aislinn Gonnot, Elamar Hakim Moully, Blaise R. Kimmel, Loan Tran, Hunter Zeleznik, Steven D. Brown, Sean D. Simpson, Milan Mrksich, Ashty S. Karim, Ramon Gonzalez, Michael Köpke, Michael C. Jewett   +17 more
doaj   +1 more source

Syntrophic Acetate-Oxidizing Microbial Consortia Enriched from Full-Scale Mesophilic Food Waste Anaerobic Digesters Showing High Biodiversity and Functional Redundancy

mSystems, 2022
Syntrophic acetate oxidation (SAO) coupled with hydrogenotrophic methanogenesis (HM) plays a vital role in the anaerobic digestion of protein-rich feedstocks such as food wastes. However, current knowledge of the biodiversity and genetic potential of the
Chao Li, Liping Hao, Fan Lü, Haowen Duan, Hua Zhang, Pinjing He   +5 more
doaj   +1 more source

Wood-Ljungdahl pathway encoding anaerobes facilitate low-cost primary production in hypersaline sediments at Great Salt Lake, Utah. [PDF]

FEMS Microbiol Ecol
Abstract Little is known of primary production in dark hypersaline ecosystems despite the prevalence of such environments on Earth today and throughout its geologic history. Here, we generated and analyzed metagenome-assembled genomes (MAGs) organized as operational taxonomic units (OTUs) from three depth intervals along a 30-cm sediment
Shoemaker A, Maritan A, Cosar S, Nupp S, Menchaca A, Jackson T, Dang A, Baxter BK, Colman DR, Dunham EC, Boyd ES.   +10 more
europepmc   +3 more sources

Ancient Metabolisms of a Thermophilic Subseafloor Bacterium

Frontiers in Microbiology, 2021
The ancient origins of metabolism may be rooted deep in oceanic crust, and these early metabolisms may have persisted in the habitable thermal anoxic aquifer where conditions remain similar to those when they first appeared.
Amy R. Smith, Amy R. Smith, Amy R. Smith, Ryan Mueller, Martin R. Fisk, Frederick S. Colwell   +5 more
doaj   +1 more source

Functional Expression of the Clostridium ljungdahlii Acetyl-Coenzyme A Synthase in Clostridium acetobutylicum as Demonstrated by a Novel In Vivo CO Exchange Activity En Route to Heterologous Installation of a Functional Wood-Ljungdahl Pathway. [PDF]

Appl Environ Microbiol, 2018
ABSTRACTEngineering the Wood-Ljungdahl pathway (WLP) in the established industrial organismClostridium acetobutylicumwould allow for the conversion of carbohydrates into butanol, acetone, and other metabolites at higher yields than are currently possible, while minimizing CO2and H2release.
Fast AG, Papoutsakis ET.
europepmc   +4 more sources