Results 101 to 110 of about 3,236,631 (398)

Anteseden Konflik Pekerjaan-keluarga dan Pengaruhnya terhadap Tingkat Kehadiran di Tempat Kerja (Studi Kasus Uptd Pendidikan Kecamatan Sagulung Kota Batam) [PDF]

open access: yes, 2017
The purpose of this study is to obtain empirical evidence about the influence of Antecedents Work Family Conflict on the Level of Attendance at Work (Case Study UPTD Sagulung District of Batam). The population of this study is 130 female teachers in UPTD
UPB, J. I. (Jurnal)
core   +1 more source

Role resources and work-family enrichment: The role of work engagement [PDF]

open access: yes, 2010
The majority of work-family research has focused on negative spillover between demands and outcomes and between the work and family domains (e.g., work-family conflict; see review by Eby, Casper, Lockwood, Bordeaux, & Brinley, 2005).
Bakker, Arnold B.   +11 more
core   +2 more sources

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Pengaruh Konflik Pekerjaan dan Konflik Keluarga Terhadap Kinerja dengan Konflik Pekerjaan Keluarga Sebagai Intervening Variabel (Studi pada Dual Career Couple di Jabodetabek)

open access: yesJurnal Manajemen dan Wirausaha, 2010
The purpose of this research is finding how the influence of working conflict towards family conflict, the influence of working conflict to working family conflict, the influence of family conflict to working family conflict and the influence of working ...
Christine W.S.   +2 more
doaj  

ANALISIS PENGARUH WORK FAMILY CONFLICT DAN FAMILY WORK CONFLICT TERHADAP INTENTION TO QUIT DENGAN BURNOUT SEBAGAI VARIABEL INTERVENING (Studi Pada Karyawan PT Telekomunikasi Indonesia Tbk. Wilayah Semarang Wilayah Semarang) [PDF]

open access: yes, 2017
The aim of this study is to describe and analyze the influence of work family conflict and family work conflict on intention to quit with burnout as an intervening variable.
WULANSARI, Hesti, YUNIAWAN , Ahyar
core  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Job Demands, Engagement, and Turnover Intentions in Polish Nurses: The Role of Work-Family Interface

open access: yesFrontiers in Psychology, 2016
Background: Poland has lower ratios of employed registered nurses per 1,000 inhabitants than the EU average. Polish nurses work under miserable conditions without assisting personnel, and they reconcile their professional demands with responsibilities ...
Anna Maria Dåderman   +2 more
doaj   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

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