Results 81 to 90 of about 17,538,337 (258)
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Single Mothers, Social Capital, and Work-Family Conflict [PDF]
The purpose of this paper is to examine work-family conflict among low-income, unmarried mothers. I examine how social capital affects work-family conflict and how both social capital and work-family conflict affect employment.
Teresa Ciabattari
core
Work-family conflict: a survey of Singaporean workers [PDF]
, 2003 Work and family are the two most important aspects of people’s lives and they often conflict. This paper examines the nature of that conflict and its effects on managers.
Skitmore, Martin, Ahmad, Sariati
core
The relationship between family-focused organisational and supervisor support and positive work-outcomes [PDF]
, 2010 This study examined the relationship between family-focused organisational and .supervisor support and the positive work outcomes, job satisfaction, affective commitment, continuous commitment and work-family ...
Mohasi, Mapalo
core +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Job Demands, Engagement, and Turnover Intentions in Polish Nurses: The Role of Work-Family Interface
Frontiers in Psychology, 2016 Background: Poland has lower ratios of employed registered nurses per 1,000 inhabitants than the EU average. Polish nurses work under miserable conditions without assisting personnel, and they reconcile their professional demands with responsibilities ...
Anna Maria Dåderman +2 more
doaj +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
, 2023 The objective of this study was to examine associations between daily fluctuations in work-family conflict (i.e. work-to-family interference [WFI] and family-to-work interference [FWI]) and daily fluctuations in toddler parenting (i.e.
Mabbe, ElienPP070001108563478020010418750000-0002-9388-646634241F5C-F0EE-11E1-A9DE-61C894A0A6B4 +2 more
core
Pengaruh Dukungan Supervisor Terhadap Work Family Conflict
Wacana: Jurnal Sosial dan Humaniora, 2016 Penelitian empiris di bidang work family conflict (konflik antara kerja dan keluarga) menunjukkan bahwa work family conflict memiliki dampak yang negatif terhadap individu, keluarga dan organisasi.
Wike Wike +3 more
doaj +1 more source