Results 81 to 90 of about 982,057 (215)

My Family Accounts Much for Me: How Does Work-to-Family Conflict Lead to Unethical Pro-Family Behavior. [PDF]

Int J Environ Res Public Health, 2023
Wang Y, Hu W, Liu Z, Luo J.
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Spillover and crossover from work overload to spouse-rated work-to-family conflict: The moderating role of cross-role trait consistency. [PDF]

Fundam Res, 2023
Huang Y, Mao Y, Zhan Y.
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Relationships Between Work-to-Family Conflict and the Food Domain for Dual-Earner Parents With Adolescent Children. [PDF]

Front Psychol, 2021
Schnettler B, Miranda-Zapata E, Orellana L, Poblete H, Lobos G, Adasme-Berríos C, Lapo M, Beroiza K.   +7 more
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

The Effect of Work Connectivity Behavior After-Hours on Employee Psychological Distress: The Role of Leader Workaholism and Work-to-Family Conflict. [PDF]

Front Public Health, 2022
Dong M, Zhang T, Li Y, Ren Z.
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Effort-reward imbalance influences perceived patient safety during the COVID-19 pandemic, mediated by work-family conflict: results from the longitudinal VOICE study

Frontiers in Organizational Psychology
BackgroundThe COVID-19 pandemic increased psychosocial burden on healthcare workers, especially related to work-family conflict, leading to significant health consequences.
Lucia Jerg-Bretzke, Paul Platzek, Marc N. Jarczok, Maximilian Kempf, Katja Weimer, Christian Hirning, Sarah Kern, Franziska Geiser, Andreas Baranowski, Yesim Erim, Eva Morawa, Kerstin Weidner, Susann Steudte-Schmiedgen, Christian Albus, Petra Beschoner   +14 more
doaj   +1 more source

Not Just Work-to-Family Conflict, But How you React to It Matters for Physical and Mental Health. [PDF]

Work Stress, 2021
Lawson KM, Lee S, Maric D.
europepmc   +1 more source