Results 51 to 60 of about 88,550,665 (246)
Objective: To determine the spillover effects of work familyconflict,work family enrichment and its effect on work family balance from one partner to another. Study Design: Cross-sectional study.
Maria Arzu +3 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Resources that individuals acquire at work can have significant effects on their own well-being and family satisfaction, and on those of their closest family relations.
Miranda Zapata, Edgardo +3 more
core
Daily Challenge/Hindrance Demands and Cognitive Wellbeing: A Multilevel Moderated Mediation Model
Based on the challenge-hindrance stressor model, this study explored the mechanism of how challenge/hindrance demands affect cognitive wellbeing on a daily basis.
Huangen Chen +3 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Perceived ambidextrous leadership and nurses’ mental health: a work-family perspective
Background Nurses are particularly at risk from stress-related problems and face high mental health problems during the COVID-19 pandemic. It is critical to pay attention to their mental health status and determine which factors are positively associated
Jiaqi Yan, Yuefeng Lian, Liangxing He
doaj +1 more source
Background and Objectives: Work-family enrichment is based on the assumption that work and family are interdependent since the gained experiences, skills, and opportunities from the workplace, improve an individualchr('39')s family life.
Fatemeh Taheri
doaj
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source

