Results 51 to 60 of about 1,307,434 (301)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

The Relationship Between Ethical Leadership and Emotional Exhaustion in a Virtual Work Environment: A Moderated Mediation Model

open access: yesSystems
The role of ethical leadership in virtual settings is not yet clearly defined, but it may be the key to addressing employees’ emotional exhaustion. In addition, to prevent emotional exhaustion, it is important to determine the role of work autonomy and ...
Carlos Santiago-Torner   +2 more
doaj   +1 more source

Surf ’s Up: Work, Life, Balance and Brand in a New Age Capitalist Organization [PDF]

open access: yes, 2010
This article reframes the notion of work/life balance through analysis of branding and the immaterial labour process in a ‘new age capitalist’ organization.
Land, Chris, Taylor, Scott
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The relationship between servant leadership and followers’ pro-social rule-breaking behavior: a study based on Chinese selected candidates

open access: yesFrontiers in Psychology
ObjectiveThis study explores the relationships among servant leadership, work autonomy, risk-taking willingness, public service motivation (PSM), and pro-social rule-breaking (PSRB), focusing on their underlying psychological mechanisms.MethodsA survey ...
Zhizhong Hu   +4 more
doaj   +1 more source

Policy-based autonomic control service [PDF]

open access: yes, 2004
Recently, there has been a considerable interest in policy-based, goal-oriented service management and autonomic computing. Much work is still required to investigate designs and policy models and associate meta-reasoning systems for policy-based ...
Badr, N., Reilly, D., Taleb-Bendiab, A.
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Work and the challenge of autonomy

open access: yesTravail et formation, 2015
Although ‘autonomy’ is rarely included as an entry in dictionaries of sociology, it is a notion that facilitates understanding of how work and, on a more general level, capitalism have evolved in modern societies. On this point, two schools of thought can be distinguished. The first of these, which is well represented through empirical studies carried
openaire   +3 more sources

From Factory to Platform: Autonomy and Control in the Digital Economy

open access: yesСоциология власти
The sociology of work paid close attention to the factory and office as the physical and social space where the labor process was directly carried out and where workers faced managerial supervision, control, and power.
Andrey V. Shevchuk
doaj   +1 more source

Workforce issues in nursing in Queensland: 2001 and 2004 [PDF]

open access: yes, 2006
[Abstract]: Aims and objectives: The aim of the study was to identify the factors impacting upon nursing work and to use the results to inform strategic planning of the Queensland Nurses Union.
Buikstra, Elizabeth   +4 more
core   +3 more sources

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