Results 41 to 50 of about 1,307,434 (301)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Exploring the Dynamics of Work Satisfaction and Innovation Among Young Lecturers in Post-Pandemic Indonesia

open access: yesJournal of Indonesian Economy and Business
Introduction/Main Objectives: This study purposes to investigate the complex relationship among work autonomy, work crafting, work satisfaction, and innovative work behaviour. Background Problems: How autonomy, crafting, and work satisfaction relate and,
Despinur Dara, Saparuddin Saparuddin
doaj   +1 more source

Can we choose evil? A discussion of the problem of radical evil as a modern and ancient problem of freedom [PDF]

open access: yes, 2004
The problem discussed in this paper emerges from work I’ve\ud done on the modern ideal of autonomy.1 I found that autonomy is often\ud seen as a morally neutral term.
Coeckelbergh, Mark
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Autonomous Capabilities for Small Unmanned Aerial Systems Conducting Radiological Response: Findings from a High-fidelity Discovery Experiment [PDF]

open access: yes, 2014
This article presents a preliminary work domain theory and identifies autonomous vehicle, navigational, and mission capabilities and challenges for small unmanned aerial systems (SUASs) responding to a radiological disaster.
Duncan, Brittany, Murphy, Robin
core   +2 more sources

Work autonomy and workplace democracy: the polarization of the goods of work autonomy in the two worlds of work

open access: yesReview of Social Economy, 2019
Political theorists have been framing the problems of unfreedom and domination at work as inconsistent with the requirements of political democracy, undermining the democratic potential of the workplace and inducing psychological and status harm. Although these are important insights, political theorists are often unwilling to frame the hierarchical ...
openaire   +3 more sources

Working time and autonomy: Lessons for the new ways of working

open access: yesEuropean Labour Law Journal, 2023
This article critically examines the relationship between autonomy and working time, with a focus on the new challenges in the world of work and explores whether traditional approaches can address new challenges. By comparing the situation of autonomous workers to known contexts, valuable lessons emerge.
openaire   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The growth and collapse of autonomy at work

open access: yesProceedings of the National Academy of Sciences
Humans hate being monitored. Autonomy is prized—including by research scientists. Yet little is known about a fundamental issue in the modern world: What is happening to job autonomy in today’s workplaces as people move from youth on to middle age and then on to older ages? It would be natural to believe that individuals in the second half
Redzo Mujcic, Andrew J. Oswald
openaire   +2 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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