Results 61 to 70 of about 725,831 (262)
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Revista de Saúde Pública, 1999 OBJETIVO: Avaliar o envelhecimento funcional (capacidade para o trabalho) associado às condições de trabalho. MÉTODOS: Responderam ao questionário "Índice de Capacidade para o Trabalho" (ICT), 807 servidores de uma instituição judiciária federal.
Silvia Meirelles Bellusci +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
South African Journal of Occupational Therapy, 2018 Introduction: Major depressive disorders (MDD) cause work disability and work loss, often resulting in unemployment. Employees with MDD are often referred to occupational therapists (OTs) to assist with functional capacity evaluation (FCE).
Enos Morankoana Ramano, Tania Buys
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Fadiga e capacidade para o trabalho em turnos fixos de doze horas
Revista de Saúde PúblicaOBJETIVO: Analisar as variáveis que interferem na percepção de fadiga e na capacidade para o trabalho em trabalhadores que executam suas atividades em turnos fixos diurnos e noturnos.
Ricardo Jorge Metzner +1 more
doaj
CAPACITY FOR WORK AND CARDIOVASCULAR RISK AMONG PREFECTURAL WORKERS ON A UNIVERSITY CAMPUS
Cogitare Enfermagem, 2015 This study aimed to ascertain the relationship of the Work Ability Index with Cardiovascular Risk in workers of the prefecture on a university campus. It is descriptive, exploratory, transversal and quantitative research undertaken in 2012 through the ...
Aline Loiola Moura +4 more
doaj +1 more source
The Third Version of the Copenhagen Psychosocial Questionnaire
Safety and Health at Work, 2019 Introduction: A new third version of the Copenhagen Psychosocial Questionnaire (COPSOQ III) has been developed in response to trends in working life, theoretical concepts, and international experience.
Hermann Burr +14 more
doaj +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source