Results 91 to 100 of about 716,253 (307)

Psychological Climate, Work Engagement, Intention to Leave and Organisational Citizenship Behaviour in Small Hospitality Businesses.

open access: yes, 2014
The aim of the current study was to examine the interrelations of important work related variables within small New Zealand based hospitality organisations in order to enhance the understanding of factors that contribute to success within these ...
Strydom, Ance
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Momentary Work Happiness as a Function of Enduring Burnout and Work Engagement [PDF]

open access: yes, 2016
The present study (N = 136) combined global measures with specific, experience-based measures to investigate how enduring job burnout and engagement influence the impact of daily work activities on momentary need satisfaction and happiness.
Oerlemans, W.G.M. (Wido)   +8 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

The Dirty Workers Among Us: The Intervening Role of Job Crafting and the Moderating Role of Leader Member Exchange in The Evaluation of Self Determination & Work Engagement

open access: yes, 2022
This study evaluates job crafting as a strategy the hospital may utilize with guest services personnel to reduce turnover, increase work engagement, and improve the quality of patient care.
Davis, DeAndrea Y.
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Employee engagement: An evaluation of the impact of cultural change initiatives at Kingsland Grange [PDF]

open access: yes, 2010
This piece of work endeavours to explore whether cultural change initiatives at Kingsland Grange have impacted employee engagement and competitive advantage.
Brophy, Mary
core  

Psychological contract breach and job resources on work engagement [PDF]

open access: yes, 2020
In today's competitive job market, talent-competed companies are continuously focusing their efforts on enhancing the work engagement of employees, where it is a vital factor that could determine the success of the organization.
Norhizam, Natasha Ellyna   +1 more
core  

Recovery resources mediate between work-study boundary congruence and wellbeing and engagement in tertiary students

open access: yes, 2021
It is important for individuals to manage the boundaries between their different roles as this affects their personal functioning and wellbeing. Little is known, however, about how students manage their role boundaries between work and study. We tested a
Chu, Moong L   +2 more
core   +1 more source

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