Results 101 to 110 of about 14,962,284 (302)
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Employee engagement: An evaluation of the impact of cultural change initiatives at Kingsland Grange [PDF]
, 2010 This piece of work endeavours to explore whether cultural change initiatives at Kingsland Grange have impacted employee engagement and competitive advantage.
Brophy, Mary
core +2 more sources
Take a break! Benefits of sleep and short breaks for daily work engagement [PDF]
, 2016 The current study investigates the benefits of a good night’s sleep and short work breaks for employees’ daily work engagement. It is hypothesized that sleep and self-initiated short breaks help restore energetic and self-regulatory resources which, in ...
DE BLOOM, Jessica +5 more
core +1 more source
Psikoislamika: Work engagement is a positive psychological condition that is important in supporting employee performance. This study aims to test the construct validity and reliability of the Indonesian version of the Utrecht Work Engagement Scale (UWES-18) on ...
Fatwa Ananta Lamusu +3 more
doaj +1 more source
Institutional Work Through Empathic Engagement
Academy of Management Proceedings, 2018 A growing body of literature examines how actors engage with institutions and how they prompt institutional change and evolution. This article takes stock of this knowledge and contributes an affective dimension to the study of how institutional entrepreneurs achieve momentum and field-level impact.
Linneberg, Mai Skjøtt; id_orcid 0000-0002-6205-6312 +2 more
openaire +3 more sources
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Burnout and work engagement in occupational therapists
, 2014 Introduction:Work engagement, characterized by vigour, dedication, and absorption, is often perceived as the opposite of burnout. Occupational therapists with burnout feel exhausted and disengaged from their work.
Henderson, J +20 more
core +1 more source
Patient Experience JournalSuicide prevention is a high priority for Veterans Health Administration (VHA). Recent data show an increase in suicide rates, especially among Veterans that had not used VHA health services and nor had received any VHA benefits.
Ali A. Poorani +3 more
doaj +1 more source