Results 101 to 110 of about 14,513,002 (301)

Engagement at work:

, 2021
This article aimed to objective a bibliometric analysis of the national production of articles on work engagement, in the period between 2010 and 2019, having as reference papers indexed based on journals of the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) and the electronic platform of the Scientific Periodicals Electronic ...
openaire   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Work engagement and burnout among Polish labour migrants [PDF]

Objectives The aim of the study was to examine the relationship between work engagement, burnout and coworker support, social climate at work, work-language proficiency and post-migration job skill change, among international migrant workers.
Wontorczyk, Antoni, Michał Kulisz, Kulisz, Michał, Antoni Wontorczyk   +3 more
core   +2 more sources

Momentary Work Happiness as a Function of Enduring Burnout and Work Engagement [PDF]

, 2016
The present study (N = 136) combined global measures with specific, experience-based measures to investigate how enduring job burnout and engagement influence the impact of daily work activities on momentary need satisfaction and happiness.
Oerlemans, W.G.M. (Wido), Oerlemans, W.G.M., Oerlemans, Wido, Oerlemans, WGM Wido, Bakker, Arnold; id_orcid, Bakker, Arnold, Bakker, AB, Bakker, A.B., Bakker, A.B. (Arnold)   +8 more
core   +3 more sources

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Psychometric test analysis of employee work engagement using the Utrecht Work Engagement Scale (UWES)

Psikoislamika
: Work engagement is a positive psychological condition that is important in supporting employee performance. This study aims to test the construct validity and reliability of the Indonesian version of the Utrecht Work Engagement Scale (UWES-18) on ...
Fatwa Ananta Lamusu, Muzwar Nawawi, Adirangga Sofyan Duda, Mohammad Rizki Dunggio   +3 more
doaj   +1 more source

Institutional Work Through Empathic Engagement

Academy of Management Proceedings, 2018
A growing body of literature examines how actors engage with institutions and how they prompt institutional change and evolution. This article takes stock of this knowledge and contributes an affective dimension to the study of how institutional entrepreneurs achieve momentum and field-level impact.
Linneberg, Mai Skjøtt; id_orcid 0000-0002-6205-6312, Trenca, Mihaela, Nørreklit, Hanne; id_orcid 0000-0002-6636-7863   +2 more
openaire   +3 more sources

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Psychological contract breach and job resources on work engagement [PDF]

, 2020
In today's competitive job market, talent-competed companies are continuously focusing their efforts on enhancing the work engagement of employees, where it is a vital factor that could determine the success of the organization.
Norhizam, Natasha Ellyna, Mohd Anuar, Mohd Ashraff   +1 more
core   +1 more source