Results 71 to 80 of about 2,573,382 (308)

Relationship between work-family conflict and quality of life: an investigation into the role of social support [PDF]

open access: yes, 2010
Purpose – The main purpose of this study is to link work-family conflict, quality of work and non-work lives, quality of life and social support (supervisor and spouse supports). Specifically, it seeks to address three different roles of social support
Ismail, Izhairi   +2 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Work-Family Conflict Impact on Psychological Safety and Psychological Well-Being: A Job Performance Model

open access: yesFrontiers in Psychology, 2020
In a modern working environment characterized by new technology and work assignments extended to personal time, employees are expected to balance multiple roles while maintaining maximum productivity.
Bojan Obrenovic   +3 more
doaj   +1 more source

Family-friendly policies for rural working mothers [PDF]

open access: yes, 2009
For working parents, family friendly work policies like paid sick days, flexible time, or medical insurance can reduce work-family conflict and lead to less absenteeism and higher productivity.
Glauber, Rebecca K.
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

The Effect of Work-Family Conflict and Family-Work Conflict on Individual Job Performance in Nurses

open access: yesSağlık ve Hemşirelik Yönetimi Dergisi
Aim: This study was conducted to determine the effect of work-family and family-work conflict levels of nurses on their individual job performance. Method: The sample of this descriptive and correlational design study consisted of 305 nurses.
Fatmanur Karaman   +2 more
doaj   +1 more source

WORK FAMILY CONFLICT - KONFLIK PERAN GANDA PADA PRAMUDI BIS WANITA [PDF]

open access: yes, 2016
Penelitian ini bertujuan untuk mengetahui gambaran konflik kerja khususnya Work Family Conflict pada pengemudi bis wanita Transjakarta. Penelitian dilakukan pada tiga subjek yang merupakan Pramudi wanita Transjakarta.
Putri, Ainindiya Dinanti
core  

The mediating role of work-family conflict in the relationship between supervisor support and job satisfaction [PDF]

open access: yes, 2010
With the increase in single mother employees, there has been an increased concern over the work-family conflict that they experience in trying to balance the demands of work and family roles. Recognizing the impact of the conflict on job satisfaction and
Ahmad, Aminah   +3 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

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