Results 51 to 60 of about 483 (209)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Work-Family Organizational Support as a Predictor of Work-Family Conflict, Enrichment, and Balance: Crossover and Spillover Effects in Dual-Income Couples

open access: yesEurope's Journal of Psychology, 2020
Dual-income families are challenged by several issues in terms of conciliation between the working environment, the family context and the management of children.
Alessandro Lo Presti   +4 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

The Relationship Between Work Engagement and Work-Family Enrichment: A Systematic Review and Meta-Analysis

open access: yesPsychological Topics
The aim of this study is to systematically summarize and analyze the relationship between work engagement and work-family enrichment. The study focuses on two aspects: the empirical direction of the relationship and the examination of mediators and ...
Tadas Vadvilavičius   +1 more
doaj   +2 more sources

Peran Core Self-Evaluation dan Dukungan Atasan terhadap Pengayaan Kerja Keluarga

open access: yesPsympathic: Jurnal Ilmiah Psikologi, 2020
In recent years, the number of women workers has increased, it means women participate in both work and family roles together. Interaction between work family life can also provide benefits in improving the quality of work-family life if managed properly.
Maudy Safira Ervinadi   +2 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Employees’ work–family enrichment in leadership context: systematic review and meta-analytical investigation

open access: yesBusiness: Theory and Practice
The aim of this study is to systematically summarize and analyse the relationship between work-family enrichment/family-work enrichment and family-supportive supervisor behaviour. A systematic literature review procedure was applied to search and review
Tadas Vadvilavičius   +1 more
doaj   +1 more source

Positive Psychological Micro-Interventions to Improve the Work–Family Interface: Use Your Resources and Count Your Blessings

open access: yesFrontiers in Psychology, 2020
The present study is designed to test the effectiveness of two positive psychological micro-interventions (“use your resources” and “count your blessings”) aimed at improving the combination of work and family roles.
Maria C. W. Peeters   +4 more
doaj   +1 more source

Reciprocation at work: the role of work to family enrichment and family role salience

open access: yesE+M Ekonomie a Management, 2018
This study investigated the main and conditional indirect effects of emotional and instrumental family related social supports from coworkers on person and task focused interpersonal citizenship behavior (ICBs). We incorporated work to family enrichment as mediator and family role salience as moderator in conditional indirect effect paths. Primary data
Aneel Kumar   +2 more
openaire   +3 more sources

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