Results 71 to 80 of about 136,179,624 (307)

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Self-beliefs and bullying : unravelling the relation between bullying, being bullied and self-concept for upper elementary school aged children

, 2006
Previous examinations of relations between bullying, victimisation, and self-concept have been flawed by erroneous research practices such as the un-attenuated use of dichotomous variables to measure relationships between continuous variables (Finger ...
Finger, Linda R., Dowson, Martin, Craven, Rhonda   +2 more
core  

Testing the Self: Digital Trials and Identity Work on Instagram

International Journal of Communication
This article examines young people’s strategies for navigating identity challenges on social media, where platforms act as testing arenas for digital self-presentation.
Raimundo Frei, Felipe Ulloa
doaj  

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

The relation of self-concept to desirable educational outcomes

, 2006
Reviewers (Byrne, 1996a, 1996b; Hattie, 1992; Marsh, Byrne, & Shavelson, 1988; Marsh & Craven, 1997; Craven, Marsh, & Burnett, 2003) consider that self-concept is multifaceted and espouse that self-concept cannot be adequately understood if its ...
Craven, Rhonda, Munns, Geoff, Ha, My Trinh, Martin, Andrew J.   +3 more
core  

The Influence of Self Efficacy on Job Performance Mediated by Intrinsic Work Motivation at Ciputra University Makassar

Accounting Profession Journal (APAJI)
This study is driven by researchers' curiosity regarding the factors influencing the job performance of lecturers and staff at Ciputra University Makassar.
Kevin Cunardy, Nabila Taufik, Bella Amalia Sasya Wardani, Carolina Novi Mustikarini   +3 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Examining the impact of employee core self-evaluations and organisational trust on work engagement

Forum Scientiae Oeconomia, 2018
This study examines the impact of core self-evaluations (CSE) and organisational trust on work engagement through the intervening steps of employee pro-social voice and defensive silence during periods of financial and economic crisis.
Anastasia Katou
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source