Results 81 to 90 of about 136,179,624 (307)

State, Security, and Economy in Afghanistan: Current Challenges, Possible Solutions

, 2007
Recommendations in this report address three broad issue areas key to ongoing state- and security-building efforts in Afghanistan: political reform, regional relationships, and international priorities.
Liechtenstein Institute on Self-Determination
core   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

A comprehensive multilevel model meta-analysis of self-concept interventions

, 2006
The efficacy of self-concept interventions has previously been examined through traditional meta-analytic methods, and a host of moderators of intervention outcomes have been identified (O’Mara, Marsh, & Craven, 2004; Haney & Durlak, 1998; Hattie, 1992).
Craven, Rhonda, Marsh, Herbert W., O'Mara, Alison J.   +2 more
core  

The Mediating Effect of Organizational Commitment and Occupational Self-Efficacy on Work Engagement

International Research Journal of Business Studies
The goal of this study is to determine the effect of occupational self-efficacy on work engagement in millennial-generation employees, with organizational commitment as a mediation variable.
Christine Winstinindah Sandroto, Athalia Anabel Alamsyah   +1 more
doaj   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Teaching sexuality to social work students : sixty years in a contact zone

, 2014
The World Health Organization affirms sexuality/reproductive health information and clinical services as human rights. This session will examine surveys of social workers’ confidence to assess, provide interventions, make referrals, and advocate for ...
Stiritz, Susan E., Pillai-Friedman, Sabitha, Turner, George W. (R19377)   +2 more
core  

Psychological Impact of Work-Integrated Learning Programmes in Malaysia: The Moderating Role of Self-Esteem on Relation between Self-Efficacy and Self-Confidence

International Journal of Educational Psychology, 2019
This study further extends a theoretical model of psychological empowerment by investigating the relationships between self-efficacy, self-confidence and self-esteem.
Amar Hisham Jaaffar, Hazril Izwar Ibrahim, Jegatheesan Rajadurai, M. Sadiq Sohail   +3 more
doaj   +1 more source

Teachers' Emotional Intelligence, Burnout, Work Engagement, and Self-Efficacy during COVID-19 Lockdown. [PDF]

Behav Sci (Basel), 2023
Geraci A, Di Domenico L, Inguglia C, D'Amico A.   +3 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source