Results 211 to 220 of about 412,423 (311)

PSA delivery agreement 12 : improve the health and wellbeing of children and young people [PDF]

, 2007

core  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

From lunch breaks to late nights: a qualitative study of how workplaces can support healthy diet, physical activity and sleep behaviours in young adults. [PDF]

BMC Public Health
Orlando C, Bajorek Z, Oxenham A, Wilson S, van Sluijs EMF, Martin A, Fairbrother H, Winpenny EM.   +7 more
europepmc   +1 more source

Editorial: Personal competences in the academic and work environment: advancing towards psychological wellbeing

Frontiers in Psychology
María del Mar Molero Jurado, María del Carmen Pérez-Fuentes, Carol D. Ryff, Pablo Molina Moreno   +3 more
openaire   +3 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Creating health-promoting spaces for change within the economy: the role of food co-operatives in England. [PDF]

Health Promot Int
Barnes A, Power M, Kennedy K.
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Support for the wellbeing of frontline healthcare workers should be incorporated in health emergency preparedness planning. [PDF]

Commun Med (Lond)
McNeil K, Nzekwu S, Gilson L, Hinga A, Oluoch D, Zhao Y, Molyneux S.   +6 more
europepmc   +1 more source

Building curriculum for excellence through positive relationships and behaviour [PDF]

, 2010

core  

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source