Results 121 to 130 of about 5,581,186 (359)

Heat pipes containing alkali metal working fluid [PDF]

open access: yes, 1981
A technique for improving high temperature evaporation-condensation heat-transfer devices which have important and unique advantage in terrestrial and space energy processing is described.
Morris, J. F.
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

A four-cylinder Stirling engine controls model [PDF]

open access: yes
A four working space, double acting piston, Stirling engine simulation was developed for controls studies. Two simulations, one for detailed fluid behavior, and a second model with simple fluid behavior but containing the four working space aspects and ...
Daniele, C. J., Lorenzo, C. F.
core   +1 more source

Carbon dioxide as the working fluid in heating and/or cooling systems [PDF]

open access: yes, 2003
Despite vigorous research the use of carbon dioxide in the market is still relatively small. This is due to legislation, and technical difficulties of developing efficient, acceptable carbon dioxide ...
Fleming, J.S.
core  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Effect of Working Fluid on Characteristics of Organic Rankine Cycle with Medium Temperature Geothermal Water

open access: yesEnergies
The total installed geothermal power plant capacity at year-end 2023 was 16,335 MW, while the forecast for the installed capacity in 2025 is 19,331 MW. In Croatia, several medium-temperature geothermal resources (geothermal water) with temperatures from ...
Zvonimir Guzović   +2 more
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Radiant heating tests of several liquid metal heat-pipe sandwich panels [PDF]

open access: yes
Integral heat pipe sandwich panels, which synergistically combine the thermal efficiency of heat pipes and the structural efficiency of honeycomb sandwich construction, were conceived as a means of alleviating thermal stress problems in the Langley ...
Basiulis, A., Camarda, C. J.
core   +1 more source

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