Results 61 to 70 of about 486,532 (254)

Exploring the relationship between working from home, mental and physical health and wellbeing: a systematic review

Public Health Research, 2023
Background Understanding the impact of working from home on health and wellbeing is of great interest to employers and employees alike, with a strong need for up-to-date guidance. The aim of this systematic review was to identify, appraise and synthesise
Blank Lindsay, Hock Emma, Cantrell Anna, Baxter Susan, Goyder Elizabeth   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Analysis of remote working practice AND CALCULATION OF ECONOMIC EFFICIENCY

Научный вестник МГТУ ГА, 2016
The article is devoted to description of working from home practice at Allianz Insurance UK и Ernst & Young, UK & Ireland. It fulfilled the analysis of the best practices in the use of new forms of social and labor relations - remote work.
K. S. Ermakov, A. V. Savyolova
doaj  

Researchers working from home: Benefits and challenges

PLOS ONE, 2020
The flexibility allowed by the mobilization of technology disintegrated the traditional work-life boundary for most professionals. Whether working from home is the key or impediment to academics’ efficiency and work-life balance became a daunting question for both scientists and their employers.
Szaszi , Barnabas, Aczel , Balazs, Van Der Lippe, Tanja, Kovacs , Marton   +3 more
openaire   +7 more sources

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Does Working from Home Work?

, 2023
Remote work (“WFH”) was often the default mode of working during the recent pandemic, because of lockdown. But beyond this one-off effect, the question remains whether remote working will endure and become part of the “new normal”. We formalize a simple company-employee work-at-home decision model, which takes into account both worker preferences and ...
Jacques Bughin, Michele Cincera
openaire   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

When Do Teleworkers Feel both Job-Satisfied and Productive? Boundary Conditions of the Telework Satisfaction-Productivity Relationship

Journal of Work and Organizational Psychology
Recent research suggests that employee well-being plays a key mediating role in transmitting the positive effects of telework on productivity. However, there are circumstances in which employee satisfaction with telework is insufficient for employee ...
Ernesto del Castillo, Sergio Madero, Alexander Lapshun, Juan I. Sanchez   +3 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source