Results 51 to 60 of about 546,386 (212)

Employment Factors Associated With Long Working Hours in France

open access: yesSafety and Health at Work, 2023
The objectives of the study were to explore the employment factors associated with long working hours, known as a risk factor for various health outcomes.
Isabelle Niedhammer   +2 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Duration of working hours: health and socio-economic Implications

open access: yesRevista Chilena de Terapia Ocupacional, 2015
A topic of relevance for occupational therapy from their bases, has been how the person distributes the time of their activities and through this reach “Occupational Balance”, recognizing its importance to the health of the human.
Christian Moretti A.
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Labour productivity in industries dependent on United States demand for Canadian exports

open access: yesEconomic and Social Reports
This article compares labour productivity from 1997 to 2024 between industries dependent on U.S. demand and other industries in the business sector. Labour productivity in this study is measured by real value added per hour worked.
Tahsin Medhi, Marc Frenette
doaj   +1 more source

Health and psychosocial effects of flexible working hours

open access: yesRevista de Saúde Pública, 2004
OBJECTIVE: To examine whether any impairments in health and social lives can be found under different kinds of flexible working hours, and whether such effects are related to specific characteristics of these working hours.
Daniela Janssen, Friedhelm Nachreiner
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

INDICATORS USED IN ANALYSING EMPLOYEES’ BEHAVIOUR IN A COMPANY [PDF]

open access: yesAnalele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2014
The acquisition and maintenance of a competitive advantage in a market economy is supported primarily by the quality of human resources, staff’s individual and collective skills and managing team’s skills.
LĂPĂDUŞI MIHAELA LOREDANA   +1 more
doaj  

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