Results 111 to 120 of about 3,652,190 (341)
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Self-Writing Machines: Technology and the Question of the Self
communication +1, 2015 In order to show that technology mediates between man and machine, I will discuss in this text a literally other or alter-knowledge system that also heavily relied on self-writing machines: spiritualism.
Christian Kassung
doaj +1 more source
FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
Supporting First-Generation Students’ Adjustment to College With High-Impact Practices [PDF]
, 2018 This qualitative case study describes some of the issues faced by incoming first-generation college students at a private, 4-year institution in the northwest.
Conefrey, Theresa
core +1 more source
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
FEBS Open Bio, EarlyView.UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source
, 2006 My visual practice is concerned with an articulation of the 'left-out-thing', remnant or blank, produced by and embedded within technologies of representation, which themselves echo the mechanisms through which an identity is formed. As automatic, 'empty
Morris, Susan
core
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
The Correlation Between Students’ Writing Self-Efficacy and Essay Writing Performance
Journal of Languages and Language TeachingSelf-efficacy in writing is an important factor for a student-writer to accomplish a writing task. However, not all studies show that writing self-efficacy and writing achievement are positively related.
Lestari Setyowati +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
A SELF-ASSESSMENT MODEL IN TEACHING ACADEMIC WRITING FOR INDONESIAN EFL LEARNERS
English Review: Journal of English Education, 2014 This self-assessment model is developed to help EFL students improve their achievement in academic writing, more particularly essay writing. In English department of Pancasakti University Tegal, academic writing is the course subject which develops ...
Taufiqulloh
doaj