Results 121 to 130 of about 2,349,231 (307)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

SINKRETISME DALAM NOVEL HUBBU KARYA MASHURI (Kajian Sosiologis, Budaya, dan Resepsi Pembaca) [PDF]

open access: yes, 2011
Dian Aksanti. S 840809203. Syncretism in Novel of Hubbu Written by Mashuri, Study of Social Culture and Reader Reception. Thesis. Surakarta: Indonesian Language Education Program, the Postgraduate of the University of Sebelas Maret Surakarta ...
Aksanti, Dian
core  

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Institutionalising ethical cultures: an investigation of formal organisational approaches [PDF]

open access: yes, 2006
This thesis examined the institutionalisation of ethics within Australian organisations. A particular focus is the role of the strategic apex, or executive level of the organisation, in establishing the environment in which an ethical culture can develop.
Segon, Michael John
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

AN ANALYSIS OF BAD LANGUAGE USED ON “8 MILE“MOVIE [PDF]

open access: yes, 2007
Language is an important tool of communication. Through language we can express our opinion, ideas, and suggestions. Language makes our communication easier.
SETIYONO, SETIYONO
core  

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Under the Queen’s Throne: Analysis of \u3cem\u3eThe Lily of Life\u3c/em\u3e [PDF]

open access: yes, 2013
This essay explores one of the older fairy tales that is not widely known by many people. The Lily of Life, published in 1913 and written by Queen Marie of Romania, touches on several topics that are still in effect in today’s society.
Lee, Seung Yeon Lana
core   +1 more source

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