Human Polyomavirus Reactivation: Disease Pathogenesis and Treatment Approaches
JC and BK polyomaviruses were discovered over 40 years ago and have become increasingly prevalent causes of morbidity and mortality in a variety of distinct, immunocompromised patient cohorts. The recent discoveries of eight new members of the Polyomaviridae family that are capable of infecting humans suggest that there are more to be discovered and ...
Cillian F. De Gascun +2 more
wiley +1 more source
WU Polyomavirus in Patients Infected with HIV or Hepatitis C Virus, Connecticut, USA, 2007
WU polyomavirus (WUPyV) was detected in 10 (8.3%) of 121 HIV-positive plasma specimens, 0 (0%) of 120 HIV-negative serum specimens, and 2 (2.5%) of 79 hepatitis C virus (HCV)–positive serum specimens.
Michael A. Miller +4 more
doaj +1 more source
Review on the Relationship between Human Polyomaviruses‐Associated Tumors and Host Immune System
The polyomaviruses are small DNA viruses that can establish latency in the human host. The name polyomavirus is derived from the Greek roots poly‐, which means “many,” and ‐oma, which means “tumours.” These viruses were originally isolated in mouse (mPyV) and in monkey (SV40).
Serena Delbue +3 more
wiley +1 more source
Detection and characterization of two chimpanzee polyomavirus genotypes from different subspecies [PDF]
The complete nucleotide sequences of three chimpanzee polyomavirus genetic variants were determined. Phylogenetic analysis indicated that the viruses form two different genotypes of ChPyV.
Ilona Deuzing +6 more
core +1 more source
Human Polyomaviruses in Skin Diseases
Polyomaviruses are a family of small, nonenveloped viruses with a circular double‐stranded DNA genome of ~5,000 base pairs protected by an icosahedral protein structure. So far, members of this family have been identified in birds and mammals. Until 2006, BK virus (BKV), JC virus (JCV), and simian virus 40 (SV40) were the only polyomaviruses known to ...
Ugo Moens +3 more
wiley +1 more source
Background DNA of the polyomaviruses WU (WUPyV) and KI (KIPyV) and of human bocavirus (HBoV) has been detected with varying frequency in respiratory tract samples of children.
Opitz Andreas +6 more
doaj +1 more source
Detection of Malawi polyomavirus sequences in secondary lymphoid tissues from Italian healthy children: a transient site of infection [PDF]
BACKGROUND: The novel Malawi polyomavirus (MWPyV) was initially detected in stool specimens from healthy children and children with gastrointestinal symptoms, mostly diarrhea, indicating that MWPyV might play a role in human gastroenteric diseases ...
Comar, M +4 more
core +2 more sources
Silencing Viral MicroRNA as a Novel Antiviral Therapy?
Viruses are intracellular parasites that ensure their existence by converting host cells into viral particle producing entities or into hiding places rendering the virus invisible to the host immune system. Some viruses may also survive by transforming the infected cell into an immortal tumour cell.
Ugo Moens, Bibekanand Mallick
wiley +1 more source
WU Polyomavirus in Children with Acute Lower Respiratory Tract Infections, South Korea
In South Korea, WU polyomavirus (WUPyV) was detected in 34 (7%) of 486 children with acute lower respiratory tract infections, 3 (4.2%) of 72 asymptomatic children, and as coinfection with other respiratory viruses in 23 (67.6%) children.
Tae Hee Han +4 more
doaj +1 more source
Burden and viral aetiology of influenza-like illness and acute respiratory infection in intensive care units [PDF]
The purpose of this investigation was to study the viral aetiology of influenza-like illness (ILI) and acute respiratory tract infection (ARTI) among patients requiring intensive care unit admission.A cross-sectional retrospective study was carried out ...
AMODIO, Emanuele +7 more
core +1 more source

