Results 121 to 130 of about 4,897 (187)

The role of the WWOX gene in leukemia and its mechanisms of action

Oncology Reports, 2013
The WW domain-containing oxidoreductase (WWOX) gene which encompasses the common human fragile site FRA16D has been proposed as a putative tumor suppressor gene, and loss of WWOX expression has been found in several types of solid cancer. As the role of WWOX in human leukemia has not yet been fully elucidated, the present study examined the expression ...
Zhaolei, Cui, Donghong, Lin, Feng, Cheng, Lingqing, Luo, Lingying, Kong, Jianping, Xu, Jianda, Hu, Fenghua, Lan   +7 more
openaire   +3 more sources

A targeted gene panel that covers coding, non-coding and short tandem repeat regions improves the diagnosis of patients with neurodegenerative diseases [PDF]

, 2019
Genetic testing for neurodegenerative diseases (NDs) is highly challenging because of genetic heterogeneity and overlapping manifestations. Targeted-gene panels (TGPs), coupled with next-generation sequencing (NGS), can facilitate the profiling of a ...
Au, Wing Chi, Chan, Anne Yin-Yan, Chan, Ho Yin Edwin, Chan, Larry W L, Chan, Ting-Fung, Cheng, Timothy H T, Li, Jing-Woei, Lin, Xiao, Mok, Vincent C T, Yim, Aldrin Kay-Yuen, Yu, Allen Chi-Shing, Yuen, Liz Y P   +11 more
core   +1 more source

WWOX Gene [PDF]

, 2020
openaire   +1 more source

Immunohistochemical assessment of tumor suppressor gene Wwox in relation to proliferative marker KI67 proteins expression in giant cell lesions of the jaws and giant cell tumor of long bones

Journal of Baghdad College of Dentistry, 2015
Background: Peripheral giant cell lesion (PGCL) and central giant cell lesion (CGCL) of the jaws have a distinct clinical behavior.Giant cell tumour (GCT) is a benign locally aggressive neoplasm affects the long bones.
Muna S Merza
doaj  

Meta-analysis of genetic variants associated with human exceptional longevity [PDF]

, 2013
Despite evidence from family studies that there is a strong genetic influence upon exceptional longevity, relatively few genetic variants have been associated with this trait.
Andersen, Stacy L., Bae1, Harold, Daw, E. Warwick, Hirose, Nobuyoshi, Kojima, Toshio, Malovini, Alberto, Perls, Thomas T, Puca, Annibale, Schupf, Nicole, Sebastiani, Paola, Sun, Fangui X.   +10 more
core   +2 more sources

Influence of WWOX/MAF genes on cognitive performance in patients with Parkinson's disease

Neurobiology of Disease
Background: Beyond its hallmark motor symptoms, Parkinson's disease (PD) encompasses a range of non-motor disturbances, particularly cognitive impairment, which significantly affects patients' quality of life. Cognitive impairment is a shared manifest in
Yun-Ting Yuan, Wei-Pin Hong, Chun-Hsiang Tan, Rwei-Ling Yu   +3 more
doaj   +1 more source

Epigenetic modifications induced by Helicobacter pylori infection through a direct microbe-gastric epithelial cells cross-talk. [PDF]

, 2013
AFFINITO, ORNELLA, ANGRISANO, TIZIANA, CHIARIOTTI, LORENZO, Florio E, KELLER, SIMONA, LEMBO, FRANCESCA, Pallante P, PERO, RAFFAELA, PERRINO, CINZIA   +8 more
core   +1 more source

Immunohistochemical evaluation of FHIT and WWOX expression in normal oral mucosa, oral epithelial dysplasia and oral squamous cell carcinoma

Journal of Baghdad College of Dentistry, 2014
Background: Oral squamous cell carcinoma is the most prevalent malignant neoplasm of the oral cavity which results from accumulated genetic and epigenetic alterations. It is not always inexorable and may be reversible if early intervention in the process
Dhaffar A Majbil, Muna S Merza
doaj  

Genome-wide QTL mapping of nine body composition and bone mineral density traits in pigs [PDF]

, 2014

core   +1 more source

Early infantile-onset epileptic encephalopathy 28 due to a homozygous microdeletion involving the WWOX gene in a region of uniparental disomy. [PDF]

Hum Mutat, 2019
Davids M, Markello T, Wolfe LA, Chepa-Lotrea X, Tifft CJ, Gahl WA, Malicdan MCV.   +6 more
europepmc   +1 more source