Results 141 to 150 of about 1,533 (168)

Stepwise phage resistance and collateral phage susceptibility in <i>Klebsiella pneumoniae</i>. [PDF]

open access: yesEmerg Microbes Infect
Yin X   +6 more
europepmc   +1 more source

Structural Organization of the Protein-tyrosine Autokinase Wzc within Escherichia coli Cells [PDF]

open access: yesJournal of Biological Chemistry, 2002
International audienceProtein Wzc from Escherichia coli is a member of a newly defined family of protein-tyrosine autokinases that are essential for surface polysaccharide production in both Gram-negative and Gram-positive bacteria.
Patricia Doublet   +2 more
exaly   +7 more sources

Autophosphorylation of the Escherichia coli Protein Kinase Wzc Regulates Tyrosine Phosphorylation of Ugd, a UDP-glucose Dehydrogenase [PDF]

open access: yesJournal of Biological Chemistry, 2003
International audienceAutophosphorylation of protein-tyrosine kinases (PTKs) involved in exopolysaccharide and capsular polysaccharide biosynthesis and transport has been observed in a number of Gram-negative and Gram-positive bacteria.
Patricia Doublet   +2 more
exaly   +9 more sources

Cells of Escherichia coli Contain a Protein-Tyrosine Kinase, Wzc, and a Phosphotyrosine-Protein Phosphatase, Wzb

open access: yesJournal of Bacteriology, 1999
International audienceTwo proteins of Escherichia coli, termed Wzc and Wzb, were analyzed for their capacity to participate in the reversible phosphorylation of proteins on tyrosine.
Patricia Doublet   +2 more
exaly   +3 more sources

Phosphorylation of Wzc, a Tyrosine Autokinase, Is Essential for Assembly of Group 1 Capsular Polysaccharides in Escherichia coli [PDF]

open access: yesJournal of Biological Chemistry, 2001
Wzc proteins are tyrosine autokinases. They are found in some important bacterial pathogens of humans and livestock as well as plant-associated bacteria, and are often encoded within gene clusters determining synthesis and assembly of capsular and extracellular polysaccharides.
Chris Whitfield
exaly   +3 more sources

Rational targeting of Wzb phosphatase and Wzc kinase interaction inhibits extracellular polysaccharides synthesis and biofilm formation in Acinetobacter baumannii

Carbohydrate Research, 2020
Acinetobacter baumannii is an opportunistic nosocomial pathogen, and responsible for high mortality and morbidity. Biofilm formation is one of the resistance determinants, where extracellular polysaccharide (EPS) is an essential component. EPS synthesis and its export is regulated by the bacterial Wza-Wzb-Wzc system.
Monalisa Tiwari   +2 more
exaly   +3 more sources

Regulation of Klebsiella pneumoniae mucoidy by the bacterial tyrosine kinase Wzc

2022
ABSTRACT Klebsiella pneumoniae is a frequent nosocomial pathogen associated with urinary tract infections (UTI), pneumonia, and septicemia. Two lineages of K. pneumoniae have emerged that challenge the treatment of these infections.
Saroj Khadka   +6 more
openaire   +1 more source

Influence of Tyrosine-Kinase Wzc Activity on Colanic Acid Production in Escherichia coli K12 Cells

Journal of Molecular Biology, 2007
Bacterial tyrosine-kinases have been demonstrated to participate in the regulation of capsule polysaccharides (CPS) and exopolysaccharides (EPS) production and export. However, discrepant data have been reported on the molecular mechanism responsible for this regulation depending on the bacterial species analyzed.
Patricia Doublet   +2 more
exaly   +3 more sources

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