Stepwise phage resistance and collateral phage susceptibility in <i>Klebsiella pneumoniae</i>. [PDF]
Yin X +6 more
europepmc +1 more source
Remodeling of the ventral attention network-default mode network as potential neural correlates of anxiety in lumbar disc herniation patients treated with lever positioning manipulation: a resting-state fMRI study. [PDF]
Zhou XC +10 more
europepmc +1 more source
Structural Organization of the Protein-tyrosine Autokinase Wzc within Escherichia coli Cells [PDF]
International audienceProtein Wzc from Escherichia coli is a member of a newly defined family of protein-tyrosine autokinases that are essential for surface polysaccharide production in both Gram-negative and Gram-positive bacteria.
Patricia Doublet +2 more
exaly +7 more sources
Autophosphorylation of the Escherichia coli Protein Kinase Wzc Regulates Tyrosine Phosphorylation of Ugd, a UDP-glucose Dehydrogenase [PDF]
International audienceAutophosphorylation of protein-tyrosine kinases (PTKs) involved in exopolysaccharide and capsular polysaccharide biosynthesis and transport has been observed in a number of Gram-negative and Gram-positive bacteria.
Patricia Doublet +2 more
exaly +9 more sources
International audienceTwo proteins of Escherichia coli, termed Wzc and Wzb, were analyzed for their capacity to participate in the reversible phosphorylation of proteins on tyrosine.
Patricia Doublet +2 more
exaly +3 more sources
Phosphorylation of Wzc, a Tyrosine Autokinase, Is Essential for Assembly of Group 1 Capsular Polysaccharides in Escherichia coli [PDF]
Wzc proteins are tyrosine autokinases. They are found in some important bacterial pathogens of humans and livestock as well as plant-associated bacteria, and are often encoded within gene clusters determining synthesis and assembly of capsular and extracellular polysaccharides.
Chris Whitfield
exaly +3 more sources
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Acinetobacter baumannii is an opportunistic nosocomial pathogen, and responsible for high mortality and morbidity. Biofilm formation is one of the resistance determinants, where extracellular polysaccharide (EPS) is an essential component. EPS synthesis and its export is regulated by the bacterial Wza-Wzb-Wzc system.
Monalisa Tiwari +2 more
exaly +3 more sources
Regulation of Klebsiella pneumoniae mucoidy by the bacterial tyrosine kinase Wzc
2022ABSTRACT Klebsiella pneumoniae is a frequent nosocomial pathogen associated with urinary tract infections (UTI), pneumonia, and septicemia. Two lineages of K. pneumoniae have emerged that challenge the treatment of these infections.
Saroj Khadka +6 more
openaire +1 more source
Influence of Tyrosine-Kinase Wzc Activity on Colanic Acid Production in Escherichia coli K12 Cells
Journal of Molecular Biology, 2007Bacterial tyrosine-kinases have been demonstrated to participate in the regulation of capsule polysaccharides (CPS) and exopolysaccharides (EPS) production and export. However, discrepant data have been reported on the molecular mechanism responsible for this regulation depending on the bacterial species analyzed.
Patricia Doublet +2 more
exaly +3 more sources

